Results 131 to 140 of about 51,947 (297)

Solar and Interplanetary Particles Re-Accelerated at the Solar Wind Termination Shock [PDF]

, 1995
We consider the acceleration of solar/interplanetary particles at the solar wind termination shock, predict the expected composition and energy spectra, and discuss possible observable ...
Mewaldt, R. A.
core  

Automated external defibrillator: Rhythm analysis and defibrillation on paediatric out-of-hospital cardiac arrest

Resuscitation Plus
Objective: This study aims to quantify the reliability of automated external defibrillators (AED) in paediatric out-of-hospital cardiac arrests (pOHCA) by evaluating the defibrillation and the shock advisory system efficacy. Furthermore, the relationship
Emma Menant, Delphine Lavignasse, Sarah Ménétré, Jean-Philippe Didon, Xavier Jouven   +4 more
doaj   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

Predictions for New Horizons’ SWAP Measurements Downstream of the Heliospheric Termination Shock

The Astrophysical Journal Letters
Currently ∼62 au from the Sun, the New Horizons spacecraft is en route to the outer heliosphere boundaries. The first boundary it will encounter is the heliospheric termination shock (HTS), where the solar wind ion (SWI) and interstellar pickup ion (PUI)
E. J. Zirnstein, D. J. McComas, B. L. Shrestha, H. A. Elliott, P. C. Brandt, S. A. Stern, A. R. Poppe, J. Parker, E. Provornikova, K. Singer, A. Verbiscer, New Horizons Heliophysics Team   +11 more
doaj   +1 more source

Photodynamic Priming and Minocycline Overcome Chemoresistance by Reprogramming the Pancreatic Tumor Immune Microenvironment In Vivo

Advanced Science, EarlyView.
Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral, Jose Quilez‐Alburquerque, Olivia Mooradian, Shivendran Vytheswarran, Badri Parshad, Girgis Obaid, Huang‐Chiao Huang, Tayyaba Hasan   +7 more
wiley   +1 more source

Injectable Hydrogel with Rapid Coagulation, Low Swelling, and High Burst Pressure Tolerance Properties for Long‐Term Management of Bleeding Wound

Advanced Science, EarlyView.
An injectable PACmC hydrogel with “rigid island‐flexible chain” architecture is developed, featuring low swelling (49.2% within 7 d), strong wet adhesion (46.5 kPa), and high burst pressure (701 mm Hg), which can achieve rapid hemostasis and long‐term sealing in rabbit and porcine models of hepatic and splenic hemorrhage.
Yang Ouyang, Wenfeng Qiu, Weiwen Liang, Xin Zhang, Weijie Liu, Zixin Chen, Yifei Li, Hui Wang, Youchen Tang, Min Li, Rongkang Huang, Zijian Chen, Binghua Ma   +12 more
wiley   +1 more source

Dumbbell‐Structured Plasmonic‐Enhanced Optical Nanoprobes Boosting Photo‐Magnetic‐Acoustic Multimodal Imaging‐Guided Photodynamic‐Photothermal Synergistic Treatment and Immunogenic Death in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study reports a novel rationally‐designed optical nanoprobe based on dumbbell‐shaped mesoporous silica‐coated gold nanorods, loaded with rare‐earth oxides, photosensitizers, and tumor‐targeted peptides, enabling plasmonic‐enhanced multimodal imaging and PTT‐PDT synergy.
Baikang Zhuang, Yubiao Yang, Wen Han, Yi Tang, Chengxin Yao, Fuli Zhao, Wenxiao Fang, Jinjie Li, Xiaolan Huo, Yiqian An, Yuanzhi Shao, Botao Gao, Jinchang Yin   +12 more
wiley   +1 more source

The Physical Significance of 'Shifted' Gradients and the Location of the Solar Wind Termination Shock [PDF]

, 1991
We use observations of anomalous cosmic-ray (ACR) oxygen from the cosmic-ray experiments on the Voyager 2 (V2) and Pioneer IO (PIO) spacecraft during 1985-1988 to investigate the physical significance of the "shifted" radial gradient The "shifted ...
Stone, E. C., Cummings, A. C., Webber, W. R.   +2 more
core  

Interstellar Pickup Ion Observations to 60 au

The Astrophysical Journal
Prior to the Solar Wind Around Pluto (SWAP) observations from New Horizons, the only significant interstellar pickup ion (PUI) observations were taken inside 5.4 au from the Ulysses and 1 au missions.
D. J. McComas, B. L. Shrestha, G. Livadiotis, J. R. Szalay, E. J. Zirnstein, H. A. Elliott, P. C. Brandt, A. R. Poppe, K. N. Singer, A. Stern, A. Verbiscer, the New Horizons Heliophysics Team   +11 more
doaj   +1 more source

Wireless, Adaptable and Fully Implantable Battery‐powered Devices for Optical Stimulation of the Spinal Cord in Small Rodents

Advanced Science, EarlyView.
Current technologies for spinal cord optogenetic stimulation rely on external power sources and face reliability constraints in freely behaving animals. Here, a fully implantable, battery‐powered optoelectronic device is introduced, enabling operation in any selected environment with wireless recharging for months‐long stimulation.
Shahriar Shalileh, Adan Moallemi, Elham Mohseni Vadeghani, Samuel Tretjakov, Brianna Tsuyuki, Alexander Golab, Benjamin Rever, Wolfram Tetzlaff, Dena Shahriari   +8 more
wiley   +1 more source