Results 61 to 70 of about 4,238,343 (270)

Common genetic variants have associations with human cortical brain regions and risk of schizophrenia

, 2019
Schizophrenia is a highly heritable mental disorder and is reported to be associated with measurements in cortical regions of the human brain. In this study, we considered genome-wide association studies to uncover genetic effects on cortical regions and
Hongtu Zhu, Lin, Zijie, Zijie Lin, Zhao, Bingxin, Wang, Shiying, Xuan Bi, Bingxin Zhao, Long Feng, Tengfei Li, Shiying Wang, Zhu, Hongtu, Bi, Xuan, Zhang, Heping, Heping Zhang, Feng, Long, Li, Tengfei   +15 more
core   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Genetic analysis on 3?-terminal flanking region of uncoupling protein 3 in different pig breeds

Chinese Science Bulletin, 2002
The 3′-terminal flanking region of porcine uncoupling protein 3 (UCP3) was cloned, the sequence data revealed 15 nucleotide substitutions among Landrace and three Chinese native pig breeds named Neijiang, Minpig and Erhualian. The continuous 9 polymorphic sites were checked by PCR-RFLP, the results indicated that Erhualian had extraordinary gene ...
openaire   +1 more source

Improved constructs for bait RNA display in a bacterial three-hybrid assay

Scientific Reports
We have previously developed a transcription-based bacterial three-hybrid (B3H) assay as a genetic approach to probe RNA–protein interactions inside of E. coli cells.
Linh D. Nguyen, Hannah LeBlanc, Katherine E. Berry   +2 more
doaj   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Genetic engineering of baker’s and wine yeasts using formaldehyde hyperresistance-mediating plasmids [PDF]

, 2009
Yeast multi-copy vectors carrying the for maldehyde-resistance marker gene SFA have proved to be a valuable tool for research on industrially used strains of Saccharomyces cerevisiae.
Schmidt, Martin, Brendel, Martin (Prof. Dr.), Grey, Martin, Cömer, Alp   +3 more
core  

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

The genetic content of chromosomal inversions across a wide latitudinal gradient [PDF]

, 2012
There is increasing evidence regarding the role of chromosomal inversions in relevant biological processes such as local adaptation and speciation. A classic example of the adaptive role of chromosomal polymorphisms is given by the clines of inversion ...
Simões, Pedro, Calabria Garcia, Gemma, Marta Pascual (88566), Balanyà Joan, Picão Osório, J., Balanyà i Maymó, Joan, Simões Pedro, João Picão-Osório, Pedro Simões (88565), Pascual Berniola, Marta, Gemma Calabria, Marta Pascual, Gemma Calabria (109704), Pascual Marta, João Picão-Osório (109707), Pedro Simões, Calabria Gemma, Picão-Osório João, Joan Balanyà, Joan Balanyà (109709)   +19 more
core   +2 more sources

Terminator Salvation [PDF]

, 2009
This is a review of Terminator Salvation (2009)
Carrière, Kathryn
core   +1 more source

Metabolic and plasmid engineering to produce D-phenyllactic acid from glucose–xylose co-substrates in Escherichia coli

Applied and Environmental Microbiology
Plasmid DNA comprises various modules, including promoter and terminator regions, replication origins, and antibiotic resistance genes as selection markers.
Shuhei Noda, Yutaro Mori, Akihiko Kondo, Daisuke Nonaka, Mayumi Dainin, Ryosuke Fujiwara, Tsutomu Tanaka, Michihiro Araki, Tomokazu Shirai   +8 more
doaj   +1 more source