Results 101 to 110 of about 853 (244)

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

An optimal gate design for the synthesis of ternary logic circuits [PDF]

2018 23rd Asia and South Pacific Design Automation Conference (ASP-DAC), 2018
Sunmean Kim, Taeho Lim, Seokhyeong Kang
openaire   +1 more source

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

Interdisciplinary Medicine, EarlyView.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou, Xuemei Ren, Yingjie Ren, Ruiping Wu, Ruiman Geng, Le Chen, Zhuo Li   +6 more
wiley   +1 more source

Climate‐Smart Destination Marketing and Community‐Based Tourism for Socio‐Economic Revitalization in Degraded Landscapes

Land Degradation &Development, EarlyView.
ABSTRACT As the global tourism industry confronts the existential imperatives of the Anthropocene, the remediation of degraded landscapes through regenerative economic models has emerged as a critical frontier in sustainability science. This research presents a rigorous empirical examination of the “restoration–revenue” paradigm, investigating the ...
Xin Sui, Tianchang Chen
wiley   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, EarlyView.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source

Technical wildness: Modernity, romanticism, and the technocratic turn in Scottish rewilding

People and Nature, EarlyView.
Abstract Technical wildness is a new and increasingly influential culture of nature. This paper marks its emergence in Scotland in the early 2020s. Focusing on Scotland's rapidly evolving land management sector, the paper traces how private rewilding companies position science‐led land management and natural capital markets as the most effective ...
Theo Stanley
wiley   +1 more source

Stair‐Climbing Wheelchairs for Enhanced Mobility: A Comprehensive Review of Fundamental Mechanisms, Design Concepts, and Performance Analysis

Journal of Field Robotics, EarlyView.
ABSTRACT People with physical disabilities face significant mobility challenges while climbing uneven surfaces and staircases. In these circumstances, traditional wheelchairs do not provide stable, safely controlled mobility, underscoring the importance of building superior stair‐climbing wheelchairs for both medical and infrastructure purposes.
Gopisetti Manikanta, S. M. Abhinandan, Anand Reddy, G. Chandana, Divya, P. Anil Kumar, Ch. Venkata Rao, Ashish Garg, Ravi C. Soni, Jogendra Kumar, Bhargav Akkinepally   +10 more
wiley   +1 more source

Carbon dots in electrochemiluminescence: Mechanisms, interface engineering, and bioanalytical applications

Responsive Materials, EarlyView.
Carbon dots are emerging as versatile electrochemiluminescent nanomaterials whose structure, surface states, and interfacial design jointly determine ECL pathways and performance. This review highlights how mechanistic understanding and materials engineering enable programmable CD‐ECL systems for bioanalysis, imaging, and future intelligent analytical ...
Yuhan Zhao, Zixuan Chen, Jun‐Jie Zhu
wiley   +1 more source

High‐Speed Rail and Spatial Equity: Unpacking the Sustainability Paradox of Land Use and Fiscal Pressure in County‐Level Cities

Sustainable Development, EarlyView.
ABSTRACT Infrastructure‐led development in rapidly urbanizing economies often generates accessibility gains that fail to translate into balanced urban outcomes, particularly when local fiscal institutions redirect those gains toward revenue‐generating land uses. Filling this gap, especially in fiscally constrained county‐level cities where land finance
Ming Xie, Xiaoxiao Liao, Zhenlin Xie
wiley   +1 more source

Regional Sustainable Economic Development in the Caribbean? A Discursive Inquiry

Sustainable Development, EarlyView.
ABSTRACT The Caribbean region is governed by several regional bodies. Among the more important organizations for small island states, where coral reefs and ocean conservation are paramount, is the Caribbean Community (CARICOM). Currently, the region is going through critical environmental changes that bring important vulnerabilities.
Peter J. Jacques, Audrey Copeland
wiley   +1 more source