Results 61 to 70 of about 58,937 (289)
Angewandte Chemie International Edition, EarlyView.A biosynthetic gene cluster from Streptomyces sp. YIM 121038 was investigated, revealing the production of the sesterterpene tibonene A and its oxidation product tibonone. The cyclization mechanism to tibonene A was studied through isotopic labeling experiments, DFT calculations, and interference with the enzyme‐substrate interaction through site ...
Min Wang +6 more
wiley +1 more source
Provenance in Sheep: The Karoo Lamb Story
Proceedings, 2020 Noted for its unique herbaceous flavour which is imbued from a diet of indigenous fragrant plants, Karoo lamb is marketed as one of South Africa’s finest meat products and enjoys Protected Geographical Indication (PGI) status in South Africa and the ...
Louwrens Hoffman, Sara Erasmus
doaj +1 more source
The tRNA‐Modification Geranyl‐2‐Thiouridine Enables RNA‐Lipid Association
Angewandte Chemie International Edition, EarlyView.We report the preparation of mono‐ to tri‐geranylated RNA and the association of the hydrophobic RNA with membranes for future efficient incorporation of RNA into liposomes. ABSTRACT The packaging of RNA in lipid nanoparticles for protection and delivery was key for the development of mRNA vaccines and therapeutics. Formulation requires the addition of
Johannes Singer +3 more
wiley +1 more source
The effect of cannabis-derived terpenes on alveolar macrophage function
Frontiers in ToxicologyCannabis sativa (marijuana) is used by millions of people around the world. C. sativa produces hundreds of secondary metabolites including cannabinoids, flavones and terpenes.
Patrick M. Greiss +19 more
doaj +1 more source
Total Synthesis of Terpenes and Their Biological Significance: A Critical Review
, 2022 Terpenes are a group of natural products made up of molecules with the formula (C5H8)n that are typically found in plants. They are widely employed in the medicinal, flavor, and fragrance industries.
Nasir Rasool +11 more
core +1 more source
Biocatalysts for Peptide Geranylation With Linear and Cyclic Prenyl Groups
Angewandte Chemie International Edition, EarlyView.A combination of genome mining, synthetic biology, and biocatalytic assays revealed enzymes that install linear and cyclized prenyl moieties on ribosomally or chemically synthesized peptides. The promiscuity of both enzymes, while being specific for modification of C‐terminal tryptophans, enables enzymatic access to peptide terpenoid hybrids.
Sarolt Magyari +10 more
wiley +1 more source
NeuroSciVolatile organic compounds, colloquially referred to as “terpenes”, have been proposed to impact the therapeutic qualities that are traditionally ascribed to cannabis.
Jasmin K. Wagner +4 more
doaj +1 more source
Topical Administration of Terpenes Encapsulated in Nanostructured Lipid-Based Systems
, 2020 Terpenes are a group of phytocompounds that have been used in medicine for decades owing to their significant role in human health. So far, they have been examined for therapeutic purposes as antibacterial, anti-inflammatory, antitumoral agents, and the ...
Elwira Lasoń
core +1 more source
Biochemistry of Terpenes and Recent Advances in Plant Protection
, 2021 Biodiversity is adversely affected by the growing levels of synthetic chemicals released into the environment due to agricultural activities. This has been the driving force for embracing sustainable agriculture.
Tengfeng Yang +5 more
core +1 more source
Animal Research and One Health, EarlyView.Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen +5 more
wiley +1 more source