Results 181 to 190 of about 4,886 (206)

Transient gene expression of recombinant terpenoid indole alkaloid enzymes inCatharanthus roseus leaves

Plant Molecular Biology Reporter, 2004
We developed a transient expression assay for Madagascar periwinkle (Catharanthus roseus [L.] G. Don.) that is based on vacuum infiltration of intact leaves with recombinantAgrobacterium tumefaciens. This simple and rapid technique was used to overexpresstryptophan decarboxylase (tdc) andstrictosidine synthase (str1) genes, which encode 2 key enzymes ...
Stefano Di Fiore, Verena Hoppmann, Rainer Fischer, Stefan Schillberg   +3 more
openaire   +1 more source

Determination of terpenoid indole alkaloids in hairy roots of Rhazya stricta (Apocynaceae) by GC‐MS

Phytochemical Analysis, 2015
AbstractIntroductionRhazya stricta Decne. (Apocynaceae) is a medicinal plant rich in terpenoid indole alkaloids (TIAs), some of which possess important pharmacological properties. The study material including transgenic hairy root cultures have been developed and their potential for alkaloid production are being investigated.ObjectiveIn this study, a ...
Akhgari, Amir, Laakso, Into, Seppänen-Laakso, Tuulikki, Yrjönen, Teijo, Vuorela, Heikki, Oksman-Caldentey, Kirsi-Marja, Rischer, Heiko   +7 more
openaire   +4 more sources

Secondary Metabolism in Cell Cultures of Some Terpenoid-Indole Alkaloid Producing Plants

1988
In the past years it has been proven that large scale culturing of plant cells is feasible. The production of shikonin (1) and of ginseng biomass (2) are examples of a commercial scale production with plant cell cultures.
R. Verpoorte, R. van der Heijden, J. Schripsema, T. van der Leer, E. J. M. Pennings, P. A. A. Harkes, S. S. Hoekstra, J. J. Meijer, H. J. G. ten Hoopen   +8 more
openaire   +1 more source

Perspectives of the Metabolic Engineering of Terpenoid Indole Alkaloids in Catharanthus roseus Hairy Roots

2013
This review looks back on how the terpenoid indole alkaloid pathway and the regulatory factors in Catharanthus roseus were identified and characterized, and how metabolic engineering, including genetic engineering and metabolic profiling, was conducted based on the gained knowledge.
Le, Zhao, Guy W, Sander, Jacqueline V, Shanks   +2 more
openaire   +2 more sources

Endophytic consortium with growth-promoting and alkaloid enhancing capabilities enhance key terpenoid indole alkaloids of Catharanthus roseus in the winter and summer seasons

Industrial Crops and Products, 2021
Sucheta Singh, Shiv Shanker Pandey, Alok Pandey   +2 more
exaly  

Terpenoid indole alkaloids, a secondary metabolite in plant defense response

2021
M. Thippeswamy, V. Rajasreelatha, Raju Krishna Chalannavar, Sudisha Jogaiah   +3 more
openaire   +1 more source

Geraniol 10-hydroxylase, a cytochrome P450 enzyme involved in terpenoid indole alkaloid biosynthesis.

FEBS letters, 2001
Geraniol 10-hydroxylase (G10H) is a cytochrome P450 monooxygenase involved in the biosynthesis of iridoid monoterpenoids and several classes of monoterpenoid alkaloids found in a diverse range of plant species. Catharanthus roseus (Madagascar periwinkle) contains monoterpenoid indole alkaloids, several of which are pharmaceutically important ...
G, Collu, N, Unver, A M, Peltenburg-Looman, R, van der Heijden, R, Verpoorte, J, Memelink   +5 more
openaire   +1 more source

Establishment of recombinant Catharanthus roseus stem cells stably overexpressing ORCA4 for terpenoid indole alkaloids biosynthesis

Plant Physiology and Biochemistry, 2023
Jianhua Zhu
exaly  

Biosynthesis—II. Terpenoid indole alkaloids

1971
J. E. Saxton, A. R. Battersby
openaire   +1 more source

Strictosidine synthase, an indispensable enzyme involved in the biosynthesis of terpenoid indole and β-carboline alkaloids

Chinese Journal of Natural Medicines, 2021
Chang-hong Wang
exaly