Results 151 to 160 of about 108,315 (301)

Terpenoid Phytosomes as Advanced Delivery Systems: Molecular Interactions, Pharmacological Potential, and Scalable Manufacturing Approaches. [PDF]

Int J Mol Sci
Sergazy S, Aliakpar S, Adekenova G, Itzhanova K, Taglialatela-Scafati O, Adekenov S.   +5 more
europepmc   +1 more source

Can Wapiti (Cervus elaphus) Browsing Stimulate the Chemical Defense of Taxus cuspidata—A Case of Northeast China Tiger and Leopard National Park

Integrative Zoology, EarlyView.
We study that browsing by wapiti reduces the growth of saplings, and it develop chemical defenses to prevent themselves browsed again. These results reduce our concern about wapiti browse T. cuspidate saplings, and provide basic data for the study of the interaction between them, and also provide theoretical basis for the population restoration and ...
Jianan Feng, Hairong Du, Xianzhe Wang, Minghai Zhang   +3 more
wiley   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

Vineyard floor mulching and removal modulates Marselan aroma formation in association with microclimate-dependent metabolic and transcriptomic regulation. [PDF]

Food Chem (Oxf)
Tian MB, Li MY, Shi N, Lu HC, Gao XT, Wang Y, Li SD, Duan CQ, Yu K, Wang J, He F.   +10 more
europepmc   +1 more source

Highly Speciated Measurements of Terpenoids Emitted from Laboratory and Mixed-Conifer Forest Prescribed Fires [PDF]

, 2019
Barsanti, Kelley C, Foster, Daniel, Goldstein, Allen H, Hatch, Lindsay E, Jen, Coty N, Kreisberg, Nathan M, Selimovic, Vanessa, Stamatis, Christos, Stephens, Scott L, Yokelson, Robert J, York, Robert A   +10 more
core  

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

In vitro evaluation of anti-trichomonal potential of Psidium guajava leaf essential oil and its main components against trophozoites of Trichomonas gallinae

Bulgarian Journal of Veterinary Medicine
Trichomoniasis is a protozoan disease caused by Trichomonas gallinae that mainly affects the upper digestive and respiratory tracts of columbiforms. Metronidazole has been used for many years for the control of trichomoniasis, however, in recent years ...
J. Akbarian, M. R. Youssefi , M. A. Tabari   +2 more
doaj   +1 more source

Integrated GC-MS and UPLC-Q-Orbitrap MS untargeted metabolomics for the comprehensive identification of metabolites and characterization of metabolic pathways in key tissues of <i>Cinnamomum cassia</i>. [PDF]

Food Chem X
Yao S, Long L, Zhu Y, Chen J, Chen L, Li L, Huang D, Ming R, Huang R, Xiao J.   +9 more
europepmc   +1 more source

Discovery of a Novel γ‐Glutamylcyclotransferase Inhibitor Plumbagin by Luminescence‐Based High‐Throughput Screening

Cancer Science, EarlyView.
A cell‐based high‐throughput screening system utilizing the luminescent probe LISA‐103 was developed to monitor γ‐glutamylcyclotransferase (GGCT) activity in cancer cells. Through this assay, plumbagin was identified as a novel GGCT inhibitor that induces cell cycle arrest and suppresses cancer cell growth. ABSTRACT γ‐Glutamylcyclotransferase (GGCT) is
Keiko Taniguchi, Yukie Nohara, Mano Horinaka, Kozue Nose, Masaya Mori, Hiromi Ii, Hiroko Kawakami, Kazuto Yano, Susumu Nakata, Taku Yoshiya, Toshiyuki Sakai   +10 more
wiley   +1 more source

Comparative metabolomics identifies enhanced ursane-type triterpenoids and antioxidant capacity in <i>Actinidia arguta</i> 'Danyang' kiwifruit. [PDF]

Front Plant Sci
Duan M, Chang J, Liang C, Yang G, Li Y, Li K, Duan X, Liu L, Yang S, Rao MJ.   +9 more
europepmc   +1 more source