The FEBS Journal, EarlyView.We have converted the only known true bacterial monoterpene synthase, cineole synthase from Streptomyces clavuligerus (bCinS, C10 substrate), to a highly competent sesquiterpene synthase (C15) with a minimum number of rational mutations. By comparison with diterpene synthases (C20), we were then able to bestow diterpene synthase activity on bCinS. This
Nicole G. H. Leferink +3 more
wiley +1 more source
Variation in terpenoids and antioxidant activity of loquat flowers during post-harvest processing: a metabolomics study. [PDF]
Front Plant SciDuan M +9 more
europepmc +1 more source
Highly Speciated Measurements of Terpenoids Emitted from Laboratory and Mixed-Conifer Forest Prescribed Fires [PDF]
, 2019 Barsanti, Kelley C +10 more
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The FEBS Journal, EarlyView.In Huh7 cells, HIF‐1α is essential as it maintains the expression of proteins involved in glycolysis and steroid/cholesterol biosynthesis both under normoxia and hypoxia. On the other hand, in HeLa cells, these pathways are induced by HIF‐1α only under hypoxia.
Ioanna‐Maria Gkotinakou +6 more
wiley +1 more source
Terpenoids: Emerging Natural Modulators for Reversing ABC Transporter-Mediated Multidrug Resistance in Cancer Chemotherapy. [PDF]
Pharmaceuticals (Basel)Ma L +8 more
europepmc +1 more source
Genomic and transcriptomic analyses reveal differential regulation of diverse terpenoid and polyketides secondary metabolites in Hericium erinaceus [PDF]
, 2017 Juan Chen +8 more
openalex +1 more source
Copaiba Oil–Resin Reduces the Alveolar Bone Damage Triggered by Apical Periodontitis in Rats
International Endodontic Journal, EarlyView.ABSTRACT Aim This study aimed to investigate the effects of copaiba oil–resin on induced apical periodontitis in rats. Methodology A total of 24 male Wistar rats were divided equally into three groups (eight animals each): control (C), apical periodontitis (AP) and apical periodontitis with copaiba administration (AP + COP).
Rayssa Maitê Farias Nazário +11 more
wiley +1 more source
Exploring differential production of alkaloids and terpenoids in Cristataspora coffeata (Berk:) Robledo (Ganodermataceae) under submerged culture. [PDF]
PLoS OneGonzález-Hernández RA +4 more
europepmc +1 more source
Metabolomics reveals biotic and abiotic elicitor effects on the soft coral Sarcophyton ehrenbergi terpenoid content [PDF]
, 2017 Mohamed A. Farag +4 more
openalex +1 more source
The targeted metabolomic profile of laticifers in rubber tree
Journal of Integrative Plant Biology, EarlyView.Targeted metabolomic profiling of rubber tree (Hevea brasiliensis) laticifers identified metabolites that were reprogramming by domestication, revealed active isoprenoid metabolism in the laticifers, and discovered loci with potential biosynthetic applications, supporting the potential of developing laticifers as bioreactors for production of valuable ...
Xiaomin Deng +9 more
wiley +1 more source