Results 101 to 110 of about 258,881 (309)

To split or not to split: CASP15 targets and their processing into tertiary structure evaluation units. [PDF]

Proteins, 2023
Kryshtafovych A, Rigden DJ.
europepmc   +1 more source

A study to assess the effectiveness of structure teaching programme regarding the knowledge and attitude of dietary management among patients undergoing hemodialysis at selected tertiary care hospital [PDF]

, 2023
Nishitha. ODDI, DR. Rajaram K G, Y Raveendra., Nirmala Ginkala, Maryline Flinsi D   +4 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Perception of the content, structure and delivery of antenatal health education received by pregnant women in Ibadan, Nigeria: a cross-sectional study

Discover Public Health
Introduction Investigating the structure of antenatal health education (AHE) received by women is crucial for improving maternal and child health outcomes.
Titilope Adenike Oluranti, Victoria Bolanle Brown, Aanuoluwapo Adeyimika Afolabi, Olufemi Idowu Oluranti, Abimbola Oyeninhun Oluwatosin   +4 more
doaj   +1 more source

Exploring effects of gut microbiota on tertiary lymphoid structure formation for tumor immunotherapy

Frontiers in Immunology
Anti-tumor immunity, including innate and adaptive immunity is critical in inhibiting tumorigenesis and development of tumor. The adaptive immunity needs specific lymph organs such as tertiary lymphoid structures (TLSs), which are highly correlated with ...
Yuqing Liu, Fan Li, Juanjuan Wang, Rongcun Yang, Rongcun Yang, Rongcun Yang   +5 more
doaj   +1 more source

APOBEC3A Catalytic Inactivity Mutation Induces Tertiary Structure Destabilization. [PDF]

ACS Med Chem Lett, 2023
Jones KFM, Shehata M, Carpenter MA, Amaro RE, Harki DA.   +4 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Prediction of Protein Function from Tertiary Structure of the Active Site in Heme Proteins by Convolutional Neural Network. [PDF]

Biomolecules, 2023
Kondo HX, Iizuka H, Masumoto G, Kabaya Y, Kanematsu Y, Takano Y.   +5 more
europepmc   +1 more source

The Tumor Immune Landscape and Architecture of Tertiary Lymphoid Structures in Urothelial Cancer [PDF]

, 2021
Nick van Dijk, Alberto Gil-Jimenez, Karīna Siliņa, Maurits L. van Montfoort, Sarah Einerhand, Lars Jonkman, Charlotte S. Voskuilen, Dennis Peters, Joyce Sanders, Yoni Lubeck, Annegien Broeks, Erik Hooijberg, Daniël J. Vis, Maries van den Broek, Lodewyk F.A. Wessels, Bas W.G. van Rhijn, Michiel S. van der Heijden   +16 more
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source