Results 21 to 30 of about 798,978 (348)

Protein secondary structure: Entropy, correlations and prediction [PDF]

open access: yes, 2003
Is protein secondary structure primarily determined by local interactions between residues closely spaced along the amino acid backbone, or by non-local tertiary interactions?
Brenner, Steven E., Crooks, Gavin E.
core   +6 more sources

Use of the 2D 1H-13C HSQC NMR Methyl Region to Evaluate the Higher Order Structural Integrity of Biopharmaceuticals

open access: yesMolecules, 2021
The higher-order structure (HOS) of protein therapeutics is directly related to the function and represents a critical quality attribute. Currently, the HOS of protein therapeutics is characterized by methods with low to medium structural resolution ...
Tsang-Lin Hwang   +3 more
doaj   +1 more source

Loop Entropy Assists Tertiary Order: Loopy Stabilization of Stacking Motifs

open access: yesEntropy, 2011
The free energy of an RNA fold is a combination of favorable base pairing and stacking interactions competing with entropic costs of forming loops. Here we show how loop entropy, surprisingly, can promote tertiary order.
Daniel P. Aalberts
doaj   +1 more source

Structural and Functional Exploration of UTS2B Gene for a Possible Role in Poultry Ascites Syndrome: In Silico Analysis [PDF]

open access: yesPoultry Science Journal
Ascites syndrome is a multifactorial disease in poultry, associated with high mortality and significant economic losses. Genomic studies have identified UTS2B gene as a candidate gene associated with ascites syndrome in poultry.
Mostafa Ghaderi-Zefrehei   +3 more
doaj   +1 more source

Morphology of sodium deoxycholate-solubilized apolipoprotein B-100 using negative stain and vitreous ice electron microscopy

open access: yesJournal of Lipid Research, 2000
The primary and secondary structures of apolipoprotein B-100 (apoB-100) are well established. Previous morphological studies have suggested that apoB is a long, flexible, threadlike molecule that encircles the low density lipoprotein (LDL) particle ...
Donald L. Gantz   +2 more
doaj   +1 more source

Conformational dynamics of the tetracycline-binding aptamer [PDF]

open access: yes, 2011
The conformational dynamics induced by ligand binding to the tetracycline-binding aptamer is monitored via stopped-flow fluorescence spectroscopy and time-correlated single photon counting experiments.
Förster, Ute   +4 more
core   +1 more source

Cloning, Expression, Sequence Analysis and Homology Modeling of the Prolyl Endoprotease from Eurygaster integriceps Puton [PDF]

open access: yes, 2014
Eurygaster integriceps Puton, commonly known as sunn pest, is a major pest of wheat in Northern Africa, the Middle East and Eastern Europe. This insect injects a prolyl endoprotease into the wheat, destroying the gluten.
Clack, Beatrice A.   +5 more
core   +3 more sources

A fisheries acoustic multi-frequency indicator to inform on large scale spatial patterns of aquatic pelagic ecosystems [PDF]

open access: yes, 2013
Fisheries acoustic instruments provide information on four major groups in aquatic ecosystems: fish with and without swim bladder (tertiary and quaternary consumers), fluidlike zooplankton (secondary consumers) and small gas bearing organisms such as ...
Bergen, Laurent, Trenkel, Verena
core   +3 more sources

STRUCTURAL SIMILARITY OF CheY-LIKE PROTEINS

open access: yesTASK Quarterly, 2016
The problem of structural similarity of polypeptide chains of low sequence similarity representing a similar 3D structural form has been the object of analysis of researchers engaged in the protein folding problem.
MATEUSZ BANACH   +2 more
doaj   +1 more source

Utilizing Protein Structure to Identify Non-Random Somatic Mutations [PDF]

open access: yes, 2013
Motivation: Human cancer is caused by the accumulation of somatic mutations in tumor suppressors and oncogenes within the genome. In the case of oncogenes, recent theory suggests that there are only a few key "driver" mutations responsible for ...
Cheng, Yuwei   +4 more
core   +2 more sources

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