Results 71 to 80 of about 325,218 (260)

The Protective Role of Poplar Propolis Against Alcohol-Induced Biochemical and Histological Changes in Liver and Testes Tissues of Rats

open access: yesErciyes Medical Journal, 2020
Objective: This study evaluated the biochemical and histopathological effects of propolis oil extract on liver and testicular tissue in rats subjected to alcohol toxicity.
Numan Baydilli   +4 more
doaj   +1 more source

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen   +10 more
wiley   +1 more source

Transcriptome Analysis of Testes and Uterus: Reproductive Dysfunction Induced by Toxoplasma gondii in Mice

open access: yesMicroorganisms, 2020
Toxoplasma gondii (T. gondii) infection in female mammals during pregnancy can result in poor pregnancy. Similarly, it can result in male reproductive disorders in male mammals.
Junjie Wang   +9 more
doaj   +1 more source

Selective Modulation of OTUB1 Noncanonical Function via a bioPhosTAC Strategy

open access: yesAdvanced Science, EarlyView.
This work positions the versatile performance of the peptide‐based bioPhosTAC platform for dissecting phosphorylation‐dependent biology and expanding the scope of induced‐proximity technologies. We demonstrated that selective manipulation of a tyrosine phosphorylation site is sufficient to propagate coordinated cellular consequences.
Seung Un Seo   +7 more
wiley   +1 more source

Histological Study on the Possible Protective Role of L-Carnitine Against Testicular Ischemia-Reperfusion Injury Induced in Rabbits [PDF]

open access: yesThe Egyptian Journal of Histology
Introduction: The torsion of the testis is a surgical emergent situation which is common; however there are no effective measures to avoid damage of the testis after untwisting this torsion. L-carnitine (LC) is an essential micronutrient with strong anti-
Mohamed Abdel Rahman   +5 more
doaj   +1 more source

Influência das etapas do beneficiamento na qualidade fisiológica e física de sementes de milho (Zea Mayz L.) [PDF]

open access: yes, 2011
TCC (graduação em Agronomia) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, 2011O trabalho foi conduzido no Laboratório de Sementes da Universidade Federal de Santa Catarina, no Centro de Ciências Agrárias, tendo como objetivo de ...
Mazurkiévicz, Juliana
core  

The proteomic study on cellular responses of the testes of zebrafish (Danio rerio) exposed to microcystin-RR

open access: yes, 2012
Microcystin-RR (MC-RR) is a commonly encountered cyanotoxin and receives increasing attention due to the risk of its bioaccumulation in aquatic animals like fish.
Zhao, Yanyan   +7 more
core   +1 more source

Natural Product Toosendanin Suppresses the Malignant Development of Skin Melanoma by Targeting BNC2 for Degradation

open access: yesAdvanced Science, EarlyView.
BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai   +7 more
wiley   +1 more source

Grtp1 Safeguards Against Paternal Reproductive Aging and Intergenerational Behavioral Deficits by Preserving Redox Homeostasis

open access: yesAdvanced Science, EarlyView.
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu   +23 more
wiley   +1 more source

Toxicidade de hidrocarbonetos monoaromáticos do petróleo sobre metamysidopsis elongata atlantica (crustacea: mysidacea) [PDF]

open access: yes, 2004
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro tecnológico. Programa de Pós-Graduação em Engenharia AmbientalO petróleo é uma mistura complexa de inúmeros compostos orgânicos, com predominância de hidrocarbonetos, e sua ...
Vieira, Francyne Carolina dos Santos
core  

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