Results 61 to 70 of about 341,009 (238)

A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics

Andrology, EarlyView.
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis, Lisa Schneider, Felix Bremmer, Daniel Nettersheim   +3 more
wiley   +1 more source

A comparison of the histopathological findings after open and percutaneous needle testicular biopsy in adult male rats

, 2000
Objective To define the histopathological changes occurring as a result of open and percutaneous needle testicular biopsy in adult rats. Materials and methods Percutaneous needle and open testicular biopsies were taken from 35 male albino rats (120-140 ...
Altay, B., HEKİMGİL, MİNE, KEFİ, AYKUT, Girgin, C., Çikili, N.   +4 more
core   +1 more source

Loss‐of‐Function Variants in CCDC189 Cause Human Oligoasthenoteratozoospermia by Disrupting Sperm Flagellar and Acrosomal Architecture

Andrology, EarlyView.
ABSTRACT Background Oligoasthenoteratozoospermia (OAT), characterized by reduced sperm count, impaired motility, and abnormal morphology, is a major cause of male infertility with substantial genetic heterogeneity. However, the underlying genetic etiology remains unresolved in a large proportion of affected individuals.
Jianteng Zhou, Ghulam Mustafa, Tingting Lin, Jingwei Ye, Huan Zhang, Hanwei Jiang, Kexin Yang, Guoning Huang, Qinghua Shi   +8 more
wiley   +1 more source

Histopathological Variation in Testicular Biopsy Done for Primary Infertility Showing Azoospermia [PDF]

Male infertility contributes to 20% of all infertility cases. It is estimated that 1% of the total male population and 10% of men seeking infertility treatment are affected by testicular failure.
Sunidhi Rohatgi, Nupur Rastogi
core   +1 more source

Androgen action via testicular arteriole smooth muscle cells is important for leydig cell function, vasomotion and testicular fluid dynamics [PDF]

, 2010
Regulation of blood flow through the testicular microvasculature by vasomotion is thought to be important for normal testis function as it regulates interstitial fluid (IF) dynamics which is an important intra-testicular transport medium.
Bergh, A., Sigrid Kilter, Richard M. Sharpe, Philippa T K Saunders, Lindsey Moffat, Sharpe, R.M., Welsh Michelle, Welsh, M., Anders Bergh, Philippa T. K. Saunders, Atanassova Nina, Saunders Philippa T. K., Atanassova, N., Smith, Lee B., Richard M Sharpe, Bergh, Anders, Bergh, Anders,, Kilter Sigrid, Sharpe, Richard M, Michelle Welsh, Sharpe Richard M., Moffat Lindsey, Lee B. Smith, Sharpe, Richard M., Moffat, Lindsey, Smith, L.B., Lee B Smith, Saunders, P.T.K., Kilter, Sigrid, Bergh Anders, Saunders, Philippa T. K.; id_orcid, Welsh, Michelle, Saunders, Philippa TK, Nina Atanassova, Smith Lee B., Smith, Lee B, Moffat, L., Kilter, S., Kilter, Sigrid,, Atanassova, Nina   +39 more
core   +1 more source

Evaluation of sperm retrieval rate with bilateral testicular sperm extraction in infertile patients with azoospermia

Iranian Journal of Reproductive Medicine, 2015
Background: About 10% to 15% of infertile men have azoospermia, which could be obstructive or non-obstructive. Diagnostic biopsy from the testis and recently testicular sperm extraction (TESE) are the most precise investigations in these patients ...
Mohammad Reza Moein, Mahmoud Reza Moein, Jalal Ghasemzadeh, Soheila Pourmasoumi   +3 more
doaj  

Testicular Fine Needle Aspiration in Evaluation of Male Infertility

Journal of Nepal Medical Association, 2009
Fine needle aspiration cytology of superficial as well as of deep seated lesions is now well recognized in diagnosis of neoplastic as well as nonneoplastic and inflammatory lesions.
Runa Jha, G Sayami
doaj   +1 more source

Parallel Liquid Biopsy Analysis of miR‐371a‐3p and Cell‐Free DNA in an Unselected Cohort of Patients With Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background Despite robust data showing strong potential to improve diagnosis and disease monitoring in testicular germ cell tumors (TGCTs), miR‐371a‐3p testing has not yet been implemented in routine clinical practice. Cell‐free DNA (cfDNA) represents another promising liquid biopsy biomarker that may provide complementary molecular ...
Laura Matouskova, Romy Kralova, Eva Parobkova, Violeta Bakardjieva‐Mihaylova, Martina Zwyrtkova, Karolina Skvarova Kramarzova, Ludmila Boublikova   +6 more
wiley   +1 more source

Beneficial value of testicular sperm extraction-AgarCyto in addition to the standard testicular biopsy for diagnosis of testicular germ cell tumors in nonobstructive azoospermia

, 2016
Contains fulltext : 172020.pdf (Publisher’s version ) (Open Access)OBJECTIVE: To study whether immunohistochemical detection of germ cell neoplasia in situ (GCNIS) in AgarCytos, made of the remnants of the testicular sperm extraction ...
Braat, D.D.M., Hulsbergen-van de Kaa, C.A., D'Hauwers, K.W.M., Hessel, M.L., Ramos, L.   +4 more
core   +1 more source

Testicular neoplasia in undescended testes of cryptorchid boys-does surgical strategy have an impact on the risk of invasive testicular neoplasia?

The Turkish Journal of Pediatrics, 2004
We investigated whether or not surgical strategy has an impact on the risk of invasive testicular neoplasia in cases of cryptorchidism. We made a database study of the incidence of testicular neoplasia at surgery for cryptorchidism in childhood ...
Dina Cortes, Jorgen Thorup, Bodil Laub Petersen   +2 more
doaj