Results 41 to 50 of about 92,654 (339)
Case 175: Testicular Lipomatosis in Cowden Disease [PDF]
Radiology, 2011 US practitioners should be aware of the characteristic appearance of testicular lipomatosis to prevent misdiagnosis of a more sinister disease; the radiologist may be the first to suggest a diagnosis of Cowden disease.
Nanda, Venkatanarasimha +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
R-spondin 1/Dickkopf-1/beta-catenin machinery is involved in testicular embryonic angiogenesis [PDF]
, 2015 Testicular vasculogenesis is one of the key processes regulating male gonad morphogenesis. The knowledge of the molecular cues underlining this phenomenon is one of today's most challenging issues and could represent a major contribution toward a better ...
Caruso, Maria +7 more
core +3 more sources
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Health ExpectationsIntroduction Testicular cancer is the most common cancer in men aged 15–44 years in many countries. Most men with testicular cancer present with a lump. Testicular symptoms are more likely to occur secondary to benign diseases like epididymo‐orchitis, a ...
Mohamad M. Saab +11 more
doaj +1 more source
Clinical evaluation of testicular torsion presenting with acute abdominal pain in young males
Asian Journal of Urology, 2019 Objective: To evaluate the features of testicular torsion presenting with acute abdominal pain and to raise awareness of testicular torsion with specific symptoms.
Fujun Wang, Zengnan Mo
doaj +1 more source
The Prognostic Role of Neutrophil-to-Lymphocyte Ratio (NLR) in Testicular Germ Cell Tumor (GCT)
Folia Medica Indonesiana, 2022 Highlights: • Neutrophil to lymphocyte ratio (NLR) has been reported by several studies for its role as a biomarker in various diseases, however, the role of NLR in testicular GCT is still unclear.
Haviv Muris Saputra, Lukman Hakim
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Epigenetic: a molecular link between testicular cancer and environmental exposures?
Frontiers in Endocrinology, 2012 In the last decades, studies in rodents have highlighted links between in utero and/or neonatal exposures to molecules that alter endocrine functions and the development of genital tract abnormalities, such as cryptorchidism, hypospadias, and impaired ...
Aurelie eVega +5 more
doaj +1 more source
Ebselen alleviates testicular pathology in mice with Zika virus infection and prevents its sexual transmission. [PDF]
PLoS Pathogens, 2018 Despite the low case fatality, Zika virus (ZIKV) infection has been associated with microcephaly in infants and Guillain-Barré syndrome. Antiviral and vaccine developments against ZIKV are still ongoing; therefore, in the meantime, preventing the disease
Yogy Simanjuntak +6 more
doaj +1 more source