Results 111 to 120 of about 70,701 (334)

Multiple Angiolipomas of the Spermatic Cord: A Case Report

IJU Case Reports, EarlyView.
ABSTRACT Introduction We report a rare case of multiple spermatic cord angiolipomas. Case Presentation An 85‐year‐old man with a history of laparoscopic right nephrectomy for renal cell carcinoma was referred for evaluation of a palpable right scrotal mass. Ultrasonography showed a single solid mass.
Kazune Teshima, Tomoaki Hakariya, Daiyu Aoki, Naoki Nishimura, Shunsuke Sato, Masahiro Nakashima   +5 more
wiley   +1 more source

Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche. [PDF]

, 2017
A major challenge in stem cell differentiation is the availability of bioassays to prove cell types generated in vitro are equivalent to cells in vivo. In the mouse, differentiation of primordial germ cell-like cells (PGCLCs) from pluripotent cells was ...
Chen, Di, Clark, Amander T, Hennebold, Jon D, Lam, Truong N, Meistrich, Marvin L, Mitchell, Jennifer M, Orwig, Kyle E, Peters, Karen A, Rojas, Ernesto J, Shetty, Gunapala, Sosa, Enrique, Sukhwani, Meena, Tailor, Ramesh C, Wu, Zhuang   +13 more
core   +2 more sources

TBCancer: A database for exploring characteristics and functions of tissue‐biased genes in cancer

iMetaOmics, EarlyView.
This study defined 10,921 tissue‐biased genes across 54 normal tissues and 41 cancer types. Tumor‐associated tissue‐biased genes exhibit downregulation, mutations, and epigenetic modifications, correlating with poor clinical outcomes. Their inactivation promotes tumorigenesis by enhancing stemness and immune evasion, highlighting their value as ...
Zhuobin Lin, Kunhua Hu, Hongyan Sun, Xiaoqiong Bao, Lin Tang, Wei Liu, Zhixiang Zuo, Zhihang Chen   +7 more
wiley   +1 more source

Histopathological analysis of testicular tumors

Journal of Pathology of Nepal, 2012
Background: Testicular cancers are rare in most countries. However, in many western countries its incidence has been increasing since the middle of the twentieth century. A definite geographic and racial distribution is seen in testicular tumors.
S Karki, RR Bhatta
doaj   +1 more source

Doxorubicin Affects Testicular Lipids with Long-Chain (C18-C22) and Very Long-Chain (C24-C32) Polyunsaturated Fatty Acids [PDF]

, 2007
Doxorubicin disrupts spermatogenesis by causing apoptosis of spermatogonia and primary spermatocytes. The aim of this study was to examine the effect of this agent on adult rat testicular lipids and their fatty acids.
Aveldaño, Marta Isabel, Maldonado, Eduardo N., Zanetti, Samanta Romina   +2 more
core   +1 more source

Imprints and DPPA3 are bypassed during pluripotency- and differentiation-coupled methylation reprogramming in testicular germ cell tumors

Genome Research, 2016
Testicular germ cell tumors (TGCTs) share germline ancestry but diverge phenotypically and clinically as seminoma (SE) and nonseminoma (NSE), the latter including the pluripotent embryonal carcinoma (EC) and its differentiated derivatives, teratoma (TE),
J. Killian, L. Dorssers, B. Trabert, A. Gillis, M. Cook, Yonghong Wang, J. Waterfall, H. Stevenson, W. Smith, Natalia Noyes, Parvathy Retnakumar, J. H. Stoop, J. Oosterhuis, P. Meltzer, K. McGlynn, Leendert H. J. Looijenga   +15 more
semanticscholar   +1 more source

Systematic review and meta‐analysis of COVID‐19 association with human semen quality: Changes in semen parameters pre‐ and post‐COVID

UroPrecision, EarlyView.
Abstract Coronavirus disease (COVID‐19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), which may infect the cells through binding with the angiotensin‐converting enzyme 2 (ACE2) receptors that can also be found in the male reproductive organs.
Wempy Supit, Tommy Supit, Sherryn Sherryn   +2 more
wiley   +1 more source

A prospective study on contrast-enhanced magnetic resonance imaging of testicular lesions: distinctive features of Leydig cell tumours [PDF]

, 2015
OBJECTIVES: Up to 20 % of incidentally found testicular lesions are benign Leydig cell tumours (LCTs). This study evaluates the role of contrast-enhanced magnetic resonance imaging (MRI) in the identification of LCTs in a large prospective cohort study.
BERNARDO, SILVIA, CANTISANI, VITO, CATALANO, Carlo, GIANFRILLI, DANIELE, ISIDORI, Andrea, LENZI, Andrea, MANGANARO, Lucia, POFI, RICCARDO, POZZA, CARLOTTA, SALDARI, MATTEO, Scialpi, M, VINCI , VALERIA   +11 more
core   +1 more source

Imatinib decreases germ cell survival and germline stem cell proliferation in rodent testis ex vivo and in vitro

Andrology, EarlyView.
Abstract Background Imatinib and dasatinib are tyrosine kinase inhibitors (TKIs) increasingly used to treat several diseases in both children and adults at fertile age. We have previously shown that imatinib has adverse effects on developing testis, and imatinib‐treated male patients have been reported to have reduced sperm counts.
Anna Eggert, Sini Laasanen, Mirja Nurmio, Aida Wahlgren, Kirsi Jahnukainen, Kim Eerola, Miisael Nieminen, Opeyemi Olotu, Noora Kotaja, Juho‐Antti Mäkelä, Jorma Toppari   +10 more
wiley   +1 more source

Testicular choriocarcinoma with pelvic and pulmonary metastases: a case report

Frontiers in Oncology
Testicular tumors represent a common form of solid tumor in young men, with choriocarcinoma of the testis being a rare, non-granulomatous germ cell tumor. It accounts for less than 0.3% of all testicular germ cell tumors.
Xin Bai, Xiao H. Liu, Hai W. Liang, Yi S. Li, Biao F. Shan, Jian M. Tang   +5 more
doaj   +1 more source