Results 31 to 40 of about 70,701 (334)

Efficacy of HDAC Inhibitors Belinostat and Panobinostat against Cisplatin-Sensitive and Cisplatin-Resistant Testicular Germ Cell Tumors

Cancers, 2020
Simple Summary There is a need for novel treatment options for patients with testicular germ cell tumors, especially for those that are resistant to standard chemotherapy, who show poor prognosis.
J. Lobo, C. Guimarães-Teixeira, D. Barros-Silva, Vera Miranda-Gonçalves, V. Camilo, Rita Guimarães, Mariana Cantante, I. Braga, J. Maurício, C. Oing, F. Honecker, D. Nettersheim, L. Looijenga, R. Henrique, C. Jerónimo   +14 more
semanticscholar   +1 more source

METTL3 May Regulate Testicular Germ Cell Tumors Through EMT and Immune Pathways

Cell Transplantation, 2020
Testicular germ cell tumors (TGCTs) are highly prevalent in young men aged 20–40 years and are one of the most common lethal solid tumors in men of this age.
Yang Luo, Yuan Sun, Lei Li, Yuling Mao
semanticscholar   +1 more source

Epigenetics and Testicular Cancer: Bridging the Gap Between Fundamental Biology and Patient Care

Frontiers in Cell and Developmental Biology, 2022
Testicular cancer is the most common solid tumor affecting young males. Most testicular cancers are testicular germ cell tumors (TGCTs), which are divided into seminomas (SGCTs) and non-seminomatous testicular germ cell tumors (NSGCTs).
Alina-Teodora Nicu, Alina-Teodora Nicu, Cosmin Medar, Mariana Carmen Chifiriuc, Mariana Carmen Chifiriuc, Mariana Carmen Chifiriuc, Mariana Carmen Chifiriuc, Gratiela Gradisteanu Pircalabioru, Liliana Burlibasa, Liliana Burlibasa   +9 more
doaj   +1 more source

Bone marrow metastasis in a patient with non‐seminomatous testicular germ cell tumor

IJU Case Reports, 2022
Introduction Metastasis to the bone marrow is rare in testicular germ cell tumor patients. We report a case of a patient with a non‐seminomatous testicular germ cell tumor who presented with bone marrow metastases after intensive chemotherapy.
Takashi Ueda, Ippei Takada, Teruki Shimizu, Saya Ito, Atsuko Fujihara, Takumi Shiraishi, Terukazu Nakamura, Osamu Ukimura   +7 more
doaj   +1 more source

Management of germ cell tumors in children: Approaches to cure [PDF]

, 2002
The introduction of cisplatinum chemotherapy and current advances in the surgical treatment have resulted in a dramatic improvement of the prognosis of children with malignant germ cell tumors (GCT).
Calaminus, G., Göbel, U., Haas, R. J., Schmidt, P., Schneider, D. T.   +4 more
core   +1 more source

PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation. [PDF]

, 2018
Germ cell tumors (GCTs) are a heterogeneous group of tumors occurring in gonadal and extragonadal locations. GCTs are hypothesized to arise from primordial germ cells (PGCs), which fail to differentiate.
Chen, Di, Clark, Amander T, Gell, Joanna J, Hunt, Timothy J, Zhao, Jasmine   +4 more
core   +2 more sources

Mixed germ cell sex cord-stromal tumors of the testis and ovary. Morphological, immunohistochemical, and molecular genetic study of seven cases [PDF]

, 2006
We present the morphological, immunohistochemical, and molecular genetic features of three cases of testicular and four cases of ovarian mixed germ cell sex cord-stromal tumors (MGSCT).
Dvorak, Vladimir, Hes, Ondrej, Kazakov, Dmitry V., Matoska, Jozef, Michal, Michal, Mukensnabl, Petr, Sima, Radek, Talerman, Alexander, Vanacek, Tomas, Zuntova, Anna   +9 more
core   +2 more sources

Burned-Out Testicular Tumor: A Case Report

Case Reports in Oncology, 2011
Germ cell tumors constitute the majority of all testicular tumors, which are relatively rare overall and are mainly encountered in young adults and teenagers.
N. Balalaa, M. Salman, W. Hassen
doaj   +1 more source

Testicular fibroma: A case report and literature review

Urology Annals, 2021
Sex cord-stromal tumors are the second most common testicular tumors after germ cell tumors. They account for about 2%–5% of adult testicular tumors. Most of these tumors are benign. The most common sex cord-stromal tumor is Leydig cell tumor.
Amal M Algarni, Noor Nabi Junejo, Sultan S Alkhateeb, Turki Omar Al-Hussain   +3 more
doaj   +1 more source

Testicular germ-cell tumours and penile squamous cell carcinoma: Appropriate management makes the difference [PDF]

, 2019
Germ-cell tumours (GCT) of the testis and penile squamous cell carcinoma (PeSCC) are a rare and a very rare uro-genital cancers, respectively. Both tumours are well defined entities in terms of management, where specific recommendations - in the form of ...
Almar E., Arveux P., Autelitano M., Baldi I., Bara S., Barchielli A., Benfatto L., Benhamou E., Bento M. J., Biasoni D., Bielska-Lasota M., Blaszczyk J., Bordoni A., Botta L., Bouchardy C., Bouvier A. -M., Bouvier V., Brewster D. H., Calleja N., Candela P., Capocaccia R., Carulla M., Catanzaro M. A., Clough-Gorr K., Colecchia M., Colonna M., Comber H., De Angelis R., de Lacerda G. F., de Munain A. L., Diaz Garcia J. M., Diba C. S., Dimitrova N., Dusek L., Engel J., Eycken E. V., Falcini F., Ferretti S., Filiberti R. A., Fusco M., Galceran J., Gatta G., Gavin A., Gennaro V., Gentilini M., Giacomin A., Gozdz S., Grosclaude P., Guizard A. -V., Hackl M., Heidrich J., Henau K., Holleczek B., Huws D. W., Iannelli A., Johannesen T. B., Jonasson J. G., Kepska K., Knijn A., Konzelmann I., Kunkler I., Lapotre-Ledoux B., Larranaga N., Leinonen M., Luttmann S., M. Ess S., Madeddu A., Magi M., Malila N., Mallone S., Mangone L., Marani E., Marcos-Gragera R., Maspero S., Maynadie M., Mazzoleni G., Michiara M., Miranda A., Molinie F., Monnereau A., Moreno-Iribas C., Mousavi M., Navarro C., Nennecke A., Nicolai N., Pannozzo F., Pierannunzio D., Piffer S., Pildava S., Primic-Zakelj M., Rachtan J., Rashbass J., Ricci P., Robaszkiewic M., Rossi S., Rugge M., Salmeron D., Sanchez M. J., Santaquilani M., Schubert-Fritschle G., Schvartz C., Sekerija M., Sensi F., Serraino D., Smailyte G., Spagnoli G., Stabenow R., Stracci F., Sutera Sardo A., Tagliabue G., Tavilla A., Torrella-Ramos A., Trama A., Tretarre B., Troussard X., Tumino R., Usala M., Velten M., Visser O., Vitale F., Woronoff A. -S., Ziino A.   +121 more
core   +1 more source