Results 31 to 40 of about 21,990 (240)

Fetal radiation exposure induces testicular cancer in genetically susceptible mice. [PDF]

open access: yesPLoS ONE, 2012
The prevalence of testicular germ cell tumors (TGCT), a common solid tissue malignancy in young men, has been annually increasing at an alarming rate of 3%.
Gunapala Shetty   +4 more
doaj   +1 more source

Genetics of testicular germ cell tumors [PDF]

open access: yesCurrent Opinion in Urology, 2019
Understanding the molecular basis underlying testicular germ cell tumors (TGCTs) may help improve patient outcomes, particularly for patients with poorer risk or chemoresistant disease. Here, we review the major contemporary advances in elucidating TGCT genetics by discussing patterns of TGCT inheritance, recent genomic and transcriptomic discoveries ...
Nirmish, Singla   +5 more
openaire   +2 more sources

Tumores testiculares na infância

open access: yesRevista do Colégio Brasileiro de Cirurgiões
Testicular and paratesticular prepuberal tumors are rare. They represent around 1% of the total of tumors of infancy. They subdivide in 2 groups: germ cells tumors and non germ cells tumors, being able to occur in all the ages, and about 75% are ...
Roni Leonardo Teixeira   +2 more
doaj   +1 more source

Primary Mediastinal Germ Cell Tumors: A Thorough Literature Review

open access: yesBiomedicines, 2023
Primary mediastinal germ cell tumors (PMGCTs) are a rare type of cancer affecting young adults. They have different molecular and clinical features compared to testicular germ cell tumors. Non-seminoma PMGCTs have the shortest 5-year overall survival and
Guliz Ozgun, Lucia Nappi
doaj   +1 more source

Spontaneous gas in a retroperitoneal mass: check the testis!

open access: yesInternational Brazilian Journal of Urology
Testicular germ cell tumor is the most common cancer in 20-to 35-years-old men. There are known risk factors such as undescended testicle(s) and history of testicular cancer.
Jérémy Dana   +3 more
doaj   +1 more source

Testicular Seminoma With Pseudocyst and Coagulation Necrosis Like Burned-out Tumor: A Case Report

open access: yesUrology Case Reports, 2016
Testicular seminoma is a relatively common testicular cancer; however, testicular seminoma with pseudocyst is an extremely rare. The ‘burned-out’ phenomenon in germ cell tumors refers to a germ cell tumor in extra-gonadal tissues with spontaneous ...
Tatsuhiko Hoshii   +3 more
doaj   +1 more source

Targeting the CMKLR1‐Mediated Signaling Rebalances Immunometabolism State in Middle‐Age Testicular Macrophages

open access: yesAdvanced Science, EarlyView.
In middle age, testicular CMKLR1⁺ macrophages exhibited a pro‐inflammatory immunometabolic profile, mediated by adipose signals associated with high BMI. However, inhibition of CMKLR1 signaling, either through Cmklr1 genetic ablation or treatment with a CMKLR1 antagonist peptide, can reverse this phenotype.
Zhendong Zhu   +10 more
wiley   +1 more source

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

open access: yesAnimal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang   +11 more
wiley   +1 more source

COMBINED TREATMENT OF A PATIENT WITH A TESTICULAR GERM CELL TUMOR WITH SIGNS OF MULTIPLE ORGAN FAILURE

open access: yesИсследования и практика в медицине, 2019
Testicular cancer is a rare malignant tumor. In the structure of general cancer incidence, this nosology accounts for about 1–1.5% of cases. Among this pathology, about 90–95% is due to testicular germ cell tumors.
T. V. Ustinova   +10 more
doaj   +1 more source

THE CLINICOPATHOLOGICAL PATTERN OF TESTICULAR TUMORS A 3-YEARS EXPERIENCE AT A TERTIARY CARE UROLOGY CENTER

open access: yesPakistan Armed Forces Medical Journal, 2021
Objective: To evaluate the clinical presentation of testicular tumors and their histological pattern present in our setup. Study Design: Case series. Place and Duration of Study: Armed Forces Institute of Urology (AFIU) Rawalpindi, from Jul 2016 to
Badar Murtaza   +6 more
doaj   +1 more source

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