Results 51 to 60 of about 70,701 (334)
Mechanisms of cisplatin sensitivity and resistance in testicular germ cell tumors
Cancer Drug Resistance, 2019 Testicular germ cell tumors (TGCTs) are a cancer pharmacology success story with a majority of patients cured even in the highly advanced and metastatic setting. Successful treatment of TGCTs is primarily due to the exquisite responsiveness of this solid
Ratnakar Singh +3 more
semanticscholar +1 more source
Fetal radiation exposure induces testicular cancer in genetically susceptible mice. [PDF]
PLoS ONE, 2012 The prevalence of testicular germ cell tumors (TGCT), a common solid tissue malignancy in young men, has been annually increasing at an alarming rate of 3%.
Gunapala Shetty +4 more
doaj +1 more source
Primary Mediastinal Germ Cell Tumors: A Thorough Literature Review
Biomedicines, 2023 Primary mediastinal germ cell tumors (PMGCTs) are a rare type of cancer affecting young adults. They have different molecular and clinical features compared to testicular germ cell tumors. Non-seminoma PMGCTs have the shortest 5-year overall survival and
Guliz Ozgun, Lucia Nappi
doaj +1 more source
Fatherhood and sperm DNA damage in testicular cancer patients [PDF]
, 2018 Testicular cancer (TC) is one of the most treatable of all malignancies and the management of the quality of life of these patients is increasingly important, especially with regard to their sexuality and fertility.
Lenzi, Andrea +3 more
core +1 more source
Andrology, 2019 Type II testicular germ cell tumors (GCTs) arise from a common precursor lesion (germ cell neoplasia in situ) and are stratified into seminomas and non‐seminomas, which differ considerably in morphology, gene expression, and epigenetic landscape.
D. Nettersheim +5 more
semanticscholar +1 more source
Lost in descent: Complications of cryptorchidism
Radiology Case Reports, 2023 Cryptorchidism is a relatively common and important clinical entity and can lead to an array of downstream complications if it is not corrected in a timely manner, most notably with the development of testicular germ cell tumors.
Lauren Facer, MD +2 more
doaj
Testicular Seminoma With Pseudocyst and Coagulation Necrosis Like Burned-out Tumor: A Case Report
Urology Case Reports, 2016 Testicular seminoma is a relatively common testicular cancer; however, testicular seminoma with pseudocyst is an extremely rare. The ‘burned-out’ phenomenon in germ cell tumors refers to a germ cell tumor in extra-gonadal tissues with spontaneous ...
Tatsuhiko Hoshii +3 more
doaj +1 more source
Annals of Oncology, 2016 BACKGROUND Testicular germ cell tumors (TGCTs) belong to the most chemosensitive solid tumors; however, a small proportion of patients fail to be cured with cisplatin-based chemotherapy.
Z. Cierna +13 more
semanticscholar +1 more source
Genetic aspects of testicular germ cell tumors [PDF]
Cell Cycle, 2008 Testicular Germ Cell Tumor (TGCT) is the most common malignant tumor in young Caucasian men with an annual increase of 3-6% in the past 50 years. Data in the literature indicate that both environmental and genetic factors acting on the primordial gonocyte/gonocyte are implicated in the etiopathogenesis of this tumour.
KRAUSZ, CSILLA GABRIELLA, Looijenga LH
openaire +4 more sources
Tumores testiculares na infância
Revista do Colégio Brasileiro de CirurgiõesTesticular and paratesticular prepuberal tumors are rare. They represent around 1% of the total of tumors of infancy. They subdivide in 2 groups: germ cells tumors and non germ cells tumors, being able to occur in all the ages, and about 75% are ...
Roni Leonardo Teixeira +2 more
doaj +1 more source