Results 71 to 80 of about 5,359,290 (244)

Predictors of Relapse and Survival in Testicular Germ cell Tumors in Children [PDF]

, 2023
Background: Testicular germ cell tumors are common solid organ malignancies in children with a survival rate of more than 90 %. This study aims to assess the predictors of relapse and survival in testicular germ cell tumors in children.
muhammad bilal shafiq, Tariq Latif, muhammad abu bakr, shazia perveen, ali, sajid, muhammad ali   +5 more
core   +1 more source

Bilateral testicular adrenal rest tumors in a patient with nonclassical congenital adrenal hyperplasia

IJU Case Reports, 2021
Introduction Solid testis tumors in post‐pubertal males usually represent germ cell malignancies; however, other uncommon or rare histologies must be considered.
Erica C Roberts, Samantha W Nealon, Jasreman Dhillon, John B Tourtelot, Bryan McIver, Wade J Sexton   +5 more
doaj   +1 more source

Testicular histopathology and its association with germ cell numbers, serum concentrations of reproductive hormones, and semen quality

Andrology, EarlyView.
Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas, Nina Mørup, Trine H. Johannsen, Anders Juul, Lise Aksglaede, Sofia B. Winge, Kristian Almstrup   +6 more
wiley   +1 more source

Unilateral testicular seminoma with simultaneous contralateral torsion: a case report

Journal of Medical Case Reports, 2012
Introduction Testicular germ cell tumors are the most common malignancies in men. Testicular torsion is also a scrotal phenomenon seen in adolescence and adulthood. The co-occurrence of these two scrotal disorders is extremely rare.
Taguchil Kazumi, Yasui Takahiro, Naiki Taku, Umemoto Yukihiro, Kojima Yoshiyuki, Kawai Noriyasu, Tozawa Keiichi, Hayashi Yutaro, Kohri Kenjiro   +8 more
doaj   +1 more source

BRD9 inhibition as potential treatment option for testicular germ cell tumors

Andrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen, Christine Sanders, Florian Fronhoffs, Kai Funke, Glen Kristiansen, Hubert Schorle   +5 more
wiley   +1 more source

Semen quality in patients with testicular cancer is associated with age and with greatly elevated levels of beta human chorionic gonadotropin

Andrology, EarlyView.
Abstract Background Poor semen quality is a well‐known feature in patients with testicular germ cell tumours (GCTs) at the time of diagnosis but the underlying biological reasons are incompletely understood. Objectives This study aimed to identify GCT‐specific clinical factors that are involved with poor semen quality in GCT patients.
Klaus‐Peter Dieckmann, Johanna Hochmuth‐Tisch, Andrea Salzbrunn, Cord Matthies, Kathrein von Kopylow, Marta Godlewska, Christian Wülfing, Uwe Pichlmeier, Armin Soave, Christian Guido Ruf   +9 more
wiley   +1 more source

Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy

Andrology, EarlyView.
ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby, Sylvianne Hennebicq, Jacqueline Saias, Florence Brugnon, Isabelle Berthaut, Myriam Daudin, Louis Bujan, Ludovic Dumont, Christine Rondanino, Aurélie Feraille, Nathalie Rives   +10 more
wiley   +1 more source

Radiotherapy in testicular germ cell tumours – a literature review [PDF]

, 2017
Testicular germ cell tumours (GCT) represent about 1–2% of malignant in men. The essential therapeutic option for early-stage GCT is radical orchiectomy (RO), except in situ ations that require immediate chemotherapy in patients with a massive ...
Pawel Wiechno, Magdalena Golawska, Joanna Jonska-Gmyrek, Grazyna Poniatowska, Tomasz Demkow, Maria Kowalska, Agnieszka Zolciak-Siwinska, Wojciech Michalski, Beata Kotowicz, Piotr Peczkowski   +9 more
core   +1 more source

Clinicopathological and Demographics Analysis of Testicular Tumors: A Single-center Experience

Acta Haematologica Oncologica Turcica
Aim: Testicular cancers are among the most prevalent solid tumors in young males. The majority of these cases involve germ cell tumors, with seminomas emerging as the predominant histological subtype. This study aimed to investigate both the clinical and
Yakup Düzköprü, Abdülkadir Koçanoğlu, Serkan Gülcü, Berna Öksüzoğlu   +3 more
doaj   +1 more source

Cryopreservation of Spermatozoa Prior and Post‐Orchiectomy in Patients With Testicular Germ Cell Cancer—Does the Timing Matter?

Andrology, EarlyView.
ABSTRACT Background Testicular germ cell cancer (TGCC) is the most frequent malignancy in young men of reproductive age. According to guidelines, semen cryopreservation should be performed prior to orchiectomy. Lack of time and local facilities as well as mental pressure are challenges in terms of fertility preservation before surgery.
Yuhe Tang, Gerald Pühse, Sabine Kliesch, Jann‐Frederik Cremers, Maria Schubert   +4 more
wiley   +1 more source