Results 81 to 90 of about 70,701 (334)

Prognostic role of programmed-death ligand 1 (PD-L1) expressing tumor infiltrating lymphocytes in testicular germ cell tumors

open access: yesOncoTarget, 2017
Purpose Testicular germ cell tumors (TGCTs) are nearly universally curable malignancies. Nevertheless, standard cisplatin-based chemotherapy is not curative in a small subgroup of patients.
M. Chovanec   +11 more
semanticscholar   +1 more source

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska   +18 more
wiley   +1 more source

Adult Pure Yolk Sac Tumor of The Testis. [PDF]

open access: yes, 2012
Adult pure yolk sac tumor (YST) is extremely rare. In childhood pure yolk sac tumors are most frequently seen, whereas component of mixed germ cell testicular tumors observed in adults.
Jagtap, SV, Kshirsagar, AY, Nikumbh, DB
core  

Prognostic factors in seminomas with special respect to HCG: Results of a prospective multicenter study [PDF]

open access: yes, 1999
Objective: In a prospective multicenter trial, it was our intention to elucidate clinical prognostic factors of seminomas with special reference to the importance of human chorionic gonadotropin (HCG) elevations in histologically pure seminomas. Methods:
Bussar-Maatz, R.   +7 more
core   +1 more source

Engineered Hydrogels Revolutionize Locoregional Cancer Immunotherapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review systematically summarizes the latest research progress on injectable hydrogels in cancer immunotherapy, highlighting their unique advantages in precise immune activation, local drug‐controlled release, and immune microenvironment remodeling. These features provide innovative solutions to overcome the bottlenecks of systemic side effects and
Jiyong Wei   +3 more
wiley   +1 more source

Seminoma metastasized to the prostate: A case report and literature review

open access: yesUrology Case Reports, 2020
The testicular seminomas are germ-cell tumors which account for approximately 50% of all testicular tumors. Most primary testicular germ cell tumors metastasize through a lymphatic system in a predictable pattern with the retroperitoneal lymph nodes ...
Ceren Durer   +5 more
doaj  

Bilateral testicular adrenal rest tumors in a patient with nonclassical congenital adrenal hyperplasia

open access: yesIJU Case Reports, 2021
Introduction Solid testis tumors in post‐pubertal males usually represent germ cell malignancies; however, other uncommon or rare histologies must be considered.
Erica C Roberts   +5 more
doaj   +1 more source

MicroRNA and transcription factor co-regulatory networks and subtype classification of seminoma and non-seminoma in testicular germ cell tumors [PDF]

open access: yes, 2020
Recent studies have revealed that feed-forward loops (FFLs) as regulatory motifs have synergistic roles in cellular systems and their disruption may cause diseases including cancer.
Eischen, Christine M.   +6 more
core   +2 more sources

Clinical presentation, management and follow-up of 83 patients with Leydig cell tumors of the testis: a prospective case-cohort study [PDF]

open access: yes, 2019
LCTs are more frequent than generally believed, are associated with male infertility, cryptorchidism and gynecomastia, and should be treated conservatively (in compliant patients) with active surveillance, which appears to be a safe alternative to ...
Cantisani, Vito   +12 more
core   +1 more source

testicular germ cell tumor

open access: yes, 2023
Supplementary Table S1: The list of 1,793 immune-related genes (IRGs) was collected from the IMMPORT database. Supplementary Table S2: The progression-free interval (PFI) data of TCGT. Supplementary Table S3: The list of highly amplified, over-expressed, and frequently mutated genes, 203 overlapping genes were identified as potential candidate TGCT ...
openaire   +2 more sources

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