Results 91 to 100 of about 10,163,401 (273)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Test results of a two-zone combustion chamber in a gas turbine engine [PDF]

open access: yesОмский научный вестник: Серия "Авиационно-ракетное и энергетическое машиностроение"
The paper presents the results of tests of the NK-16ST engine with an experimental two-zone combustion chamber. The design features of the combustion chamber, the engine fuel system, the testing methodology and the results of measuring the ...
A. N. Markushin, A. V. Baklanov
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Reviving health mediation during the COVID-19 crisis and beyond: an implementation study in deprived neighbourhoods of Marseille, France

open access: yesFrontiers in Public Health
IntroductionIn 2020, during France’s COVID-19 response, healthcare professionals from a hospital and an association initiated health mediation interventions in Marseille’s vulnerable neighbourhoods, funded by the regional health authorities.
Alix Fruleux   +13 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

DESIGN AND ANALYSIS QUALITY SYSTEM OF STUDENT INFORMATION PROCESSING DATA NEW STUDENT SMK MUHAMMADIYAH 3 YOGYAKARTA [PDF]

open access: yes, 2012
This research aims to design and analyze websites new Student Information System Acceptance SMK Muhammadiyah 3 Yogyakarta with PHP and MySQL that can manage data on the implementation of the prospective student Admission. This research is Research and
Reny, Karlinawati
core  

Testing bounded arboricity

open access: yes, 2017
In this paper we consider the problem of testing whether a graph has bounded arboricity. The family of graphs with bounded arboricity includes, among others, bounded-degree graphs, all minor-closed graph classes (e.g.
Eden, Talya, Levi, Reut, Ron, Dana
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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