The reference distributions of Maurer's universal statistical test and its improved tests [PDF]
Maurer's universal statistical test can widely detect non-randomness of given sequences. Coron proposed an improved test, and further Yamamoto and Liu proposed a new test based on Coron's test. These tests use normal distributions as their reference distributions, but the soundness has not been theoretically discussed so far. Additionally, Yamamoto and
arxiv
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
Empirical likelihood test for community structure in networks [PDF]
Network data, characterized by interconnected nodes and edges, is pervasive in various domains and has gained significant popularity in recent years. In network data analysis, testing the presence of community structure in a network is one of the important research tasks. Existing tests are mainly developed for unweighted networks.
arxiv
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
Comparison of different goodness-of-fit tests [PDF]
Various distribution free goodness-of-fit test procedures have been extracted from literature. We present two new binning free tests, the univariate three-region-test and the multivariate energy test. The power of the selected tests with respect to different slowly varying distortions of experimental distributions are investigated. None of the tests is
arxiv
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti+3 more
wiley +1 more source
Development of wheelchair caster testing equipment and preliminary testing of caster models
Background: Because of the adverse environmental conditions present in less-resourced environments (LREs), the World Health Organization (WHO) has recommended that specialised wheelchair test methods may need to be developed to support product quality ...
Anand Mhatre+2 more
doaj +1 more source
Multiple Monte Carlo Testing with Applications in Spatial Point Processes [PDF]
The rank envelope test (Myllym\"aki et al., Global envelope tests for spatial processes, arXiv:1307.0239 [stat.ME]) is proposed as a solution to multiple testing problem for Monte Carlo tests. Three different situations are recognized: 1) a few univariate Monte Carlo tests, 2) a Monte Carlo test with a function as the test statistic, 3) several Monte ...
arxiv
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
A Logical Approach to Generating Test Plans [PDF]
During the execution of a test plan, a test manager may decide to drop a test case if its result can be inferred from already executed test cases. We show that it is possible to automatically generate a test plan to exploit the potential to justifiably drop a test case and thus reduce the number of test cases.
arxiv