Results 71 to 80 of about 20,928,352 (345)

Development of Point of Care Testing Device for Neurovascular Coupling From Simultaneous Recording of EEG and NIRS During Anodal Transcranial Direct Current Stimulation

IEEE Journal of Translational Engineering in Health and Medicine, 2015
This paper presents a point of care testing device for neurovascular coupling (NVC) from simultaneous recording of electroencephalogram (EEG) and near infrared spectroscopy (NIRS) during anodal transcranial direct current stimulation (tDCS). Here, anodal
Utkarsh Utkarsh Jindal Jindal, Mehak Mehak Sood Sood, Anirban Anirban Dutta Dutta, Shubhajit Roy Shubhajit Roy Chowdhury Chowdhury   +3 more
semanticscholar   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Review of Progress of Optical Brain-Computer Interface Technology and Prospects for Medical Device Testing Technology

Zhongguo yiliao qixie zazhi
Optical brain-computer interface (OBCI) technology is a new cross-cutting frontier technology that achieves information interaction between the human brain and external devices through neuroengineering based on optical methods. Among them, brain-computer
Yiqiao WANG, Yunping MI, Xinyan ZHANG, Bin ZHAO, Hao LI, Xun LIU   +5 more
doaj   +1 more source

Gigacycle fatigue behavior of a cast aluminum alloy under biaxial bending: experiments with a new piezoelectric fatigue testing device

, 2016
To C. Bathias memory Many components in several industries are loaded in VHCF regime, either at high frequencies (wheels of high speed trains, blades in aircraft turbojet engines, etc.) or at lower frequencies during decades (artificial heart, mooring ...
C. Brugger, T. Palin-Luc, P. Osmond, M. Blanc   +3 more
semanticscholar   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

MSAmix-Net: Diabetic Retinopathy Classification

IEEE Access
Diabetic retinopathy (DR) is a very common complication of diabetes that can lead to retinal damage, affecting vision. If not detected and diagnosed in time, it may result in visual impairment.
Jianyun Gao, Shu Li, Yiwen Chen, Rongwu Xiang   +3 more
doaj   +1 more source

Development of a Very High Cycle Fatigue (VHCF) multiaxial testing device

, 2016
The very high cycle region of the S-N fatigue curve has been the subject of intensive research on the last years, with special focus on axial, bending, torsional and fretting fatigue tests.
M. Vieira, M. Freitas, L. Reis, A. Ribeiro   +3 more
semanticscholar   +1 more source

Assessment of knee laxity using a robotic testing device: a comparison to the manual clinical knee examination

Knee Surgery, Sports Traumatology, Arthroscopy, 2015
PurposeThe purpose of this study was to collect knee laxity data using a robotic testing device. The data collected were then compared to the results obtained from manual clinical examination.MethodsTwo human cadavers were studied.
T. Branch, S. Stinton, R. Siebold, H. Freedberg, C. Jacobs, W. Hutton   +5 more
semanticscholar   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Analysis of Engine Knock Sensor

Communications, 2018
The paper deals with design of a simple device for the detection of this disorder. In the beginning of the paper the effect of the undesirable detonation combustion in internal combustion engines is described.
Daniel Korenciak, Miroslav Gutten, Juraj Adamec, Adam Glowacz, Adam Cichy   +4 more
doaj   +1 more source