Results 61 to 70 of about 4,147,366 (254)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

MSAmix-Net: Diabetic Retinopathy Classification

open access: yesIEEE Access
Diabetic retinopathy (DR) is a very common complication of diabetes that can lead to retinal damage, affecting vision. If not detected and diagnosed in time, it may result in visual impairment.
Jianyun Gao   +3 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Design of an efficient neuromuscular electrical stimulation system

open access: yesDianzi Jishu Yingyong
The article presents an efficient system for neuromuscular electrical stimulation (NMES). NMES operates by harnessing the electrical excitability of nerve cells to stimulate the nerves that control muscles through pulsed electrical currents, thereby ...
Li Dongming   +4 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Research Progress of 3D-Printed Polyetheretherketone in Implantable Medical Devices

open access: yesZhongguo yiliao qixie zazhi
Polyetheretherketone (PEEK) has emerged as a thermoplastic material of choice in the realm of implantable medical devices, owing to its high biocompatibility and exceptional mechanical strength.
Shangda ZHANG
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Research on Electromagnetic Compatibility Immunity Testing Methods for Proton Therapy System

open access: yesZhongguo yiliao qixie zazhi
The proton therapy system has significant clinical advantages over traditional tumor radiation treatment equipment and is also far more complex in terms of system architecture.
Weiwei LU
doaj   +1 more source

Repetitive Availability Demonstration Testing Procedure

open access: yes, 2018
The proposed availability demonstration test (ADT) is an extension of the work of Usher and Taylor [Usher, J.S. and Taylor, G.D., "Availability Demonstration Testing," Qual. Reliab. Eng. Int., Vol. 22, No. 4, 2006, pp.
Usher, J. S.   +3 more
core   +1 more source

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