Results 31 to 40 of about 185,233 (313)

Testis tumor associated to microlithiasis

open access: yesRevista Paulista de Pediatria, 2013
OBJECTIVE: To discuss the relationship between testicular microlithiasis and testis tumors in children and to consider the chances of testis preserving surgery in specific cases.
Lisieux Eyer de Jesus   +4 more
doaj   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

open access: yesFEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili   +2 more
wiley   +1 more source

The computational analysis of human testis transcriptome reveals closer ties to pluripotency

open access: yesJournal of Human Reproductive Sciences, 2012
Aims: The purpose of this study was to identify the differentially expressed genes (DEG) in human testis and also evaluate the relationship between human testis, human Embryonic Stem Cells (hESC), mouse testis and mouse ESCs (mESC).
M T Anand, Burra VLS Prasad
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Partial rejuvenation of the spermatogonial stem cell niche after gender-affirming hormone therapy in trans women

open access: yeseLife
Although the impact of gender-affirming hormone therapy (GAHT) on spermatogenesis in trans women has already been studied, data on its precise effects on the testicular environment is poor.
Emily Delgouffe   +8 more
doaj   +1 more source

Sex Hormones Associate With Amyotrophic Lateral Sclerosis Risk and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) risk differs by sex and age, implicating sex hormones as potential modifiers. This study examined plasma levels of biologically active sex hormones and their association with ALS odds and survival in cases (females n = 131, males n = 189) and controls (females n = 138, males n = 150) from the University of ...
Stephen A. Goutman   +5 more
wiley   +1 more source

Gene Expression of E2F1 in Chicken and Mouse Testes at Various Developmental Stages

open access: yesThe Journal of Poultry Science, 2010
E2F1 (Adenoviral E2 promoter binding transcription factor 1), mediating cell proliferation and p53-dependent/independent apoptosis, has been shown to be involved in spermatogenesis in mouse testis.
Heba A. Basha   +3 more
doaj   +1 more source

Generation of a Highly Biomimetic Organoid, Including Vasculature, Resembling the Native Immature Testis Tissue

open access: yesCells, 2021
The creation of a testis organoid (artificial testis tissue) with sufficient resemblance to the complex form and function of the innate testis remains challenging, especially using non-rodent donor cells.
Tat-Chuan Cham   +3 more
doaj   +1 more source

Enzyme‐Regulated Extended Swelling of Hydrogels for Dehiscence‐Less Tissue Expansions

open access: yesAdvanced Functional Materials, EarlyView.
An interpenetrating hydrogel network with swelling under regulation by enzymatic degradation (INSURED) is fabricated to avoid dehiscence. INSURED remains structurally intact post‐implantation, while HYAL injection enables control over the onset and rate of swelling.
Byung Ik Park   +10 more
wiley   +1 more source

Dysregulation of angiogenesis-specific signalling in adult testis results in xenograft degeneration

open access: yesScientific Reports, 2017
Ectopic xenografting of testis is a feasible option for preservation of male fertility and angiogenesis plays a pivotal role in xenograft survival and functionality.
Lalitha Devi   +2 more
doaj   +1 more source

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