Results 51 to 60 of about 359,825 (361)

The computational analysis of human testis transcriptome reveals closer ties to pluripotency

open access: yesJournal of Human Reproductive Sciences, 2012
Aims: The purpose of this study was to identify the differentially expressed genes (DEG) in human testis and also evaluate the relationship between human testis, human Embryonic Stem Cells (hESC), mouse testis and mouse ESCs (mESC).
M T Anand, Burra VLS Prasad
doaj   +1 more source

Identifizierung und Charakterisierung eines neuen Bindeproteins für zyklische Nukleotide [PDF]

open access: yes, 2007
Cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate are important intracellular messengers. Binding of cyclic nucleotides controls the activity of protein kinases, ion channels and guanine-nucleotide-exchange factors in many cells ...
Debowski, Katharina
core  

Novas perspectivas no diagnóstico do hipogonadismo pediátrico masculino: a importância do AMH como marcador de células de Sertoli [PDF]

open access: yes, 2011
Sertoli cells are the most active cell population in the testis during infancy and childhood. In these periods of life, hypogonadism can only be evidenced without stimulation tests, if Sertoli cell function is assessed.
Grinspon, Romina, Rey, Rodolfo Alberto
core   +2 more sources

Lymphoma of the testis [PDF]

open access: yesCancer, 1970
The prognosis for lymphoma clinically localized to the testis at the time of original diagnosis is relatively favorable after orchiectomy and radiation therapy to the regional lymph nodes the previously held belief that life expectancy is poor for men with testicular lymphoma was due to failure in most reports to separate survival of those with ...
J M, Kiely   +3 more
openaire   +2 more sources

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

open access: yesFEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li   +10 more
wiley   +1 more source

Partial rejuvenation of the spermatogonial stem cell niche after gender-affirming hormone therapy in trans women

open access: yeseLife
Although the impact of gender-affirming hormone therapy (GAHT) on spermatogenesis in trans women has already been studied, data on its precise effects on the testicular environment is poor.
Emily Delgouffe   +8 more
doaj   +1 more source

HAGE, a cancer/testis antigen expressed at the protein level in a variety of cancers [PDF]

open access: yes, 2010
The search for novel tumour antigens that are either uniquely expressed or over-expressed in a wide variety of tumours is still ongoing. Because of their expression in a broad spectrum of cancers and limited expression in normal tissues, cancer/testis ...
Badoual, C   +6 more
core  

A surge of late-occurring meiotic double-strand breaks rescues synapsis abnormalities in spermatocytes of mice with hypomorphic expression of SPO11 [PDF]

open access: yes, 2015
Meiosis is the biological process that, after a cycle of DNA replication, halves the cellular chromosome complement, leading to the formation of haploid gametes.
Barchi, Marco   +9 more
core   +3 more sources

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

open access: yesFEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili   +2 more
wiley   +1 more source

Gene Expression of E2F1 in Chicken and Mouse Testes at Various Developmental Stages

open access: yesThe Journal of Poultry Science, 2010
E2F1 (Adenoviral E2 promoter binding transcription factor 1), mediating cell proliferation and p53-dependent/independent apoptosis, has been shown to be involved in spermatogenesis in mouse testis.
Heba A. Basha   +3 more
doaj   +1 more source

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