Results 51 to 60 of about 279,657 (361)

The computational analysis of human testis transcriptome reveals closer ties to pluripotency

open access: yesJournal of Human Reproductive Sciences, 2012
Aims: The purpose of this study was to identify the differentially expressed genes (DEG) in human testis and also evaluate the relationship between human testis, human Embryonic Stem Cells (hESC), mouse testis and mouse ESCs (mESC).
M T Anand, Burra VLS Prasad
doaj   +1 more source

Identification and characterization of human testis derived circular RNAs and their existence in seminal plasma

open access: yesScientific Reports, 2016
Circular RNAs (circRNAs) have emerged as novel molecules of interest in gene regulation as other noncoding RNAs. Though they have been explored in some species and tissues, the expression and functions of circRNAs in human reproductive systems remain ...
W. Dong   +4 more
semanticscholar   +1 more source

Enzyme‐Regulated Extended Swelling of Hydrogels for Dehiscence‐Less Tissue Expansions

open access: yesAdvanced Functional Materials, EarlyView.
An interpenetrating hydrogel network with swelling under regulation by enzymatic degradation (INSURED) is fabricated to avoid dehiscence. INSURED remains structurally intact post‐implantation, while HYAL injection enables control over the onset and rate of swelling.
Byung Ik Park   +10 more
wiley   +1 more source

Partial rejuvenation of the spermatogonial stem cell niche after gender-affirming hormone therapy in trans women

open access: yeseLife
Although the impact of gender-affirming hormone therapy (GAHT) on spermatogenesis in trans women has already been studied, data on its precise effects on the testicular environment is poor.
Emily Delgouffe   +8 more
doaj   +1 more source

Generation of a Highly Biomimetic Organoid, Including Vasculature, Resembling the Native Immature Testis Tissue

open access: yesCells, 2021
The creation of a testis organoid (artificial testis tissue) with sufficient resemblance to the complex form and function of the innate testis remains challenging, especially using non-rodent donor cells.
Tat-Chuan Cham   +3 more
doaj   +1 more source

Controlled Release of Human Dental Pulp Stem Cell‐Derived Exosomes from Hydrogels Attenuates Temporomandibular Joint Osteoarthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia   +7 more
wiley   +1 more source

Gene Expression of E2F1 in Chicken and Mouse Testes at Various Developmental Stages

open access: yesThe Journal of Poultry Science, 2010
E2F1 (Adenoviral E2 promoter binding transcription factor 1), mediating cell proliferation and p53-dependent/independent apoptosis, has been shown to be involved in spermatogenesis in mouse testis.
Heba A. Basha   +3 more
doaj   +1 more source

Thiolated Hyaluronic Acid: A Gateway for Targeted Killing of Staphylococcus aureus on the Race for Surface Colonization

open access: yesAdvanced Healthcare Materials, EarlyView.
Thiolated hyaluronic acid (HAMS) synthesized and characterized by NMR, solubility, thiol content, and pKa, is degraded by Staphylococcal hyaluronate lyase but not by mammalian hyaluronidase. Coating polyphosphate–M23 phage endolysin nanoparticles (M23‐PP) with HAMS confers Staphylococcus aureus responsiveness.
Mariana Blanco Massani   +11 more
wiley   +1 more source

Dysregulation of angiogenesis-specific signalling in adult testis results in xenograft degeneration

open access: yesScientific Reports, 2017
Ectopic xenografting of testis is a feasible option for preservation of male fertility and angiogenesis plays a pivotal role in xenograft survival and functionality.
Lalitha Devi   +2 more
doaj   +1 more source

Differential expression of estrogen receptor α and progesterone receptor in the normal and cryptorchid testis of a dog

open access: yesLaboratory Animal Research, 2016
Descending of the testes is an important process for spermatogenesis and cryptorchidism is one of the most relevant genital defects in dogs. In a previous study, we observed abnormal morphology and proliferation of Sertoli cells in a cryptorchid testis ...
Hyo Young Jung   +7 more
doaj   +1 more source

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