Results 21 to 30 of about 183,045 (246)

Free Testosterone Reflects Metabolic as well as Ovarian Disturbances in Subfertile Oligomenorrheic Women

International Journal of Endocrinology, 2018
Background. Diagnosing polycystic ovary syndrome (PCOS) is based on ovulatory dysfunction, ovarian ultrasound data, and androgen excess. Total testosterone is frequently used to identify androgen excess, but testosterone is mainly bound to sex hormone ...
L. Antonio, S. Pauwels, M. R. Laurent, D. Vanschoubroeck, I. Jans, J. Billen, F. Claessens, B. Decallonne, Diane De Neubourg, P. Vermeersch, D. Vanderschueren   +10 more
doaj   +1 more source

Testosterone trajectories and reference ranges in a large longitudinal sample of male adolescents.

PLoS ONE, 2014
PurposePubertal dynamics plays an important role in physical and psychological development of children and adolescents. We aim to provide reference ranges of plasma testosterone in a large longitudinal sample.
Ammar Khairullah, Laura Cousino Klein, Suzanne M Ingle, Margaret T May, Courtney A Whetzel, Elizabeth J Susman, Tomáš Paus   +6 more
doaj   +1 more source

Serum Testosterone and Cortisol Concentrations After Single-Dose Administration of 100-Mg Transdermal Testosterone in Healthy Men

Frontiers in Pharmacology, 2019
The growing interest in testosterone's effects on men's social behaviors, in particular aggressive, risk-taking, or status maintenance behaviors, is accompanied by a paucity of dose-dependent pharmacokinetic data. Examining the neurophysiological effects
Andrei A. Puiu, Andrei A. Puiu, Sina Radke, Mikhail Votinov, Mikhail Votinov, Ute Habel, Ute Habel, Beate Herpertz-Dahlmann, Bruce Turetsky, Kerstin Konrad, Kerstin Konrad   +10 more
doaj   +1 more source

Testosterone protects mice against zika virus infection and suppresses the inflammatory response in the brain

iScience, 2022
Summary: Testosterone is essential to human growth and development as well as immune regulation. Zika virus (ZIKV), an emerging arbovirus associated with neurological complications including neuroinflammation, can also cause testicular damage and ...
Bohan Zheng, Jiajun Sun, Haoran Luo, Ling’en Yang, Qi Li, Luping Zhang, Youhui Si, Shengbo Cao, Jing Ye   +8 more
doaj   +1 more source

Fabrication of silastic testosterone enanthate implants to achieve virilizing levels of serum testosterone in swine

MethodsX
The aim of this study was to create a continuous drug delivery system that would yield serum testosterone levels in sexually mature, female pigs consistent with serum testosterone levels of human transgender men.
Nirvana Mahabir, Annie E. Newell-Fugate
doaj   +1 more source

Transcriptomic and lipid profiling analysis reveals a functional interplay between testosterone and growth hormone in hypothyroid liver

Frontiers in Endocrinology, 2023
Preclinical and clinical studies suggest that hypothyroidism might cause hepatic endocrine and metabolic disturbances with features that mimic deficiencies of testosterone and/or GH.
Leandro Fernández-Pérez, Leandro Fernández-Pérez, Borja Guerra, Borja Guerra, Carlota Recio, Juan José Cabrera-Galván, Irma García, Juan Vladimir De La Rosa, Antonio Castrillo, Antonio Castrillo, Antonio Castrillo, Diego Iglesias-Gato, Mario Díaz   +12 more
doaj   +1 more source

The enhancing effects of testosterone in exposure treatment for social anxiety disorder: a randomized proof-of-concept trial

Translational Psychiatry, 2021
Individuals with a social anxiety disorder (SAD) show hypofunctioning of the hypothalamus–pituitary-gonadal (HPG) axis, which is linked to social fear and avoidance behavior.
Moniek H. M. Hutschemaekers, Rianne A. de Kleine, Gert-Jan Hendriks, Mirjam Kampman, Karin Roelofs   +4 more
doaj   +1 more source

Removal of Steroid Hormone Micropollutants by an Electrochemical Carbon Nanotube Membrane Flow‐Through Reactor: Role of Concentration and Degradation Mechanisms

Advanced Functional Materials, EarlyView.
A flow‐through electrochemical membrane reactor equipped with a carbon nanotube membrane eliminates the mass transfer limitation, achieving removals >97.5% for steroid hormone (SH) micropollutants through electrochemical adsorption and degradation, over a broad initial concentration varying from 50 to 106 ng L−1.
Siqi Liu, David Jassby, Andrea I. Schäfer   +2 more
wiley   +1 more source

An Overview of Testosterone Therapy

American Journal of Men's Health, 2016
Millions of men, as a result of the natural aging process, injury, illness, and medical therapies, experience a decline in testosterone levels that necessitate a need for testosterone supplementation therapy (TST).
O. Danny Lee PhD, APRN-BC, CNE, Ken Tillman PhD, RN   +1 more
doaj   +1 more source

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source