Results 21 to 30 of about 186,135 (293)

Serum Testosterone and Cortisol Concentrations After Single-Dose Administration of 100-Mg Transdermal Testosterone in Healthy Men

Frontiers in Pharmacology, 2019
The growing interest in testosterone's effects on men's social behaviors, in particular aggressive, risk-taking, or status maintenance behaviors, is accompanied by a paucity of dose-dependent pharmacokinetic data. Examining the neurophysiological effects
Andrei A. Puiu, Andrei A. Puiu, Sina Radke, Mikhail Votinov, Mikhail Votinov, Ute Habel, Ute Habel, Beate Herpertz-Dahlmann, Bruce Turetsky, Kerstin Konrad, Kerstin Konrad   +10 more
doaj   +1 more source

Fabrication of silastic testosterone enanthate implants to achieve virilizing levels of serum testosterone in swine

MethodsX
The aim of this study was to create a continuous drug delivery system that would yield serum testosterone levels in sexually mature, female pigs consistent with serum testosterone levels of human transgender men.
Nirvana Mahabir, Annie E. Newell-Fugate
doaj   +1 more source

Testosterone protects mice against zika virus infection and suppresses the inflammatory response in the brain

iScience, 2022
Summary: Testosterone is essential to human growth and development as well as immune regulation. Zika virus (ZIKV), an emerging arbovirus associated with neurological complications including neuroinflammation, can also cause testicular damage and ...
Bohan Zheng, Jiajun Sun, Haoran Luo, Ling’en Yang, Qi Li, Luping Zhang, Youhui Si, Shengbo Cao, Jing Ye   +8 more
doaj   +1 more source

The enhancing effects of testosterone in exposure treatment for social anxiety disorder: a randomized proof-of-concept trial

Translational Psychiatry, 2021
Individuals with a social anxiety disorder (SAD) show hypofunctioning of the hypothalamus–pituitary-gonadal (HPG) axis, which is linked to social fear and avoidance behavior.
Moniek H. M. Hutschemaekers, Rianne A. de Kleine, Gert-Jan Hendriks, Mirjam Kampman, Karin Roelofs   +4 more
doaj   +1 more source

Transcriptomic and lipid profiling analysis reveals a functional interplay between testosterone and growth hormone in hypothyroid liver

Frontiers in Endocrinology, 2023
Preclinical and clinical studies suggest that hypothyroidism might cause hepatic endocrine and metabolic disturbances with features that mimic deficiencies of testosterone and/or GH.
Leandro Fernández-Pérez, Leandro Fernández-Pérez, Borja Guerra, Borja Guerra, Carlota Recio, Juan José Cabrera-Galván, Irma García, Juan Vladimir De La Rosa, Antonio Castrillo, Antonio Castrillo, Antonio Castrillo, Diego Iglesias-Gato, Mario Díaz   +12 more
doaj   +1 more source

Sex Hormones Associate With Amyotrophic Lateral Sclerosis Risk and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) risk differs by sex and age, implicating sex hormones as potential modifiers. This study examined plasma levels of biologically active sex hormones and their association with ALS odds and survival in cases (females n = 131, males n = 189) and controls (females n = 138, males n = 150) from the University of ...
Stephen A. Goutman, David G. Stouffer, Dae‐Gyu Jang, Jihyun Park, Benjamin J. Murdock, Richard J. Auchus   +5 more
wiley   +1 more source

Removal of Steroid Hormone Micropollutants by an Electrochemical Carbon Nanotube Membrane Flow‐Through Reactor: Role of Concentration and Degradation Mechanisms

Advanced Functional Materials, EarlyView.
A flow‐through electrochemical membrane reactor equipped with a carbon nanotube membrane eliminates the mass transfer limitation, achieving removals >97.5% for steroid hormone (SH) micropollutants through electrochemical adsorption and degradation, over a broad initial concentration varying from 50 to 106 ng L−1.
Siqi Liu, David Jassby, Andrea I. Schäfer   +2 more
wiley   +1 more source

An Overview of Testosterone Therapy

American Journal of Men's Health, 2016
Millions of men, as a result of the natural aging process, injury, illness, and medical therapies, experience a decline in testosterone levels that necessitate a need for testosterone supplementation therapy (TST).
O. Danny Lee PhD, APRN-BC, CNE, Ken Tillman PhD, RN   +1 more
doaj   +1 more source

Germanane Quantum Dots Promote Metabolic Reprogramming of Immune Cells Toward Regulatory T Cells and Suppress Inflammation In Vitro and In Vivo

Advanced Functional Materials, EarlyView.
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava, Alireza Rafieerad, Weiang Yan, Keshav Narayan Alagarsamy, Qingdong Guan, Leena Regi Saleth, Michel Aliani, Sanjiv Dhingra   +7 more
wiley   +1 more source

Salivary testosterone levels in preadolescent children

BMC Pediatrics, 2002
Background Saliva reflects the plasma free fraction of testosterone which is biologically active, and available for uptake by tissues. Testosterone concentration in saliva, though differing slightly from the concentration of unbound testosterone in serum,
Dohnányiová Monika, Putz Zdenek, Pastor Karol, Ostatníková Daniela, Mat'ašeje Anna, Hampl Richard   +5 more
doaj   +1 more source