Results 31 to 40 of about 231,442 (307)

Testosterone and the Heart [PDF]

Methodist DeBakey Cardiovascular Journal, 2017
Testosterone (T) has a number of important effects on the cardiovascular system. In men, T levels begin to decrease after age 40, and this decrease has been associated with an increase in all-cause mortality and cardiovascular (CV) risk. Low T levels in men may increase their risk of developing coronary artery disease (CAD), metabolic syndrome, and ...
Travis, Goodale, Archana, Sadhu, Steven, Petak, Richard, Robbins   +3 more
openaire   +2 more sources

A Validated Age-Related Normative Model for Male Total Testosterone Shows Increasing Variance but No Decline after Age 40 Years [PDF]

, 2014
The diagnosis of hypogonadism in human males includes identification of low serum testosterone levels, and hence there is an underlying assumption that normal ranges of testosterone for the healthy population are known for all ages.
Wallace, W Hamish B, Li, Lucy Q, Lucy Q Li, Thomas W Kelsey, Richard A Anderson, Whelan, Ashley, Ashley Whelan, Lucy Q. Li (641265), Ashley Whelan (641266), Mitchell, Rod T, Richard A. Anderson (64013), Wallace, Hamish, Kelsey, Thomas W, W. Hamish B. Wallace (254093), Richard A. Anderson, Thomas W. Kelsey, Rod T. Mitchell, B. Wallace, Anderson, Richard, W Hamish B Wallace, Anderson, Richard A, W. Hamish, Rod T Mitchell, Thomas W. Kelsey (254095), Rod T. Mitchell (164314), Lucy Q. Li, Kelsey, Thomas W; id_orcid   +26 more
core   +1 more source

Serum Testosterone and Cortisol Concentrations After Single-Dose Administration of 100-Mg Transdermal Testosterone in Healthy Men

Frontiers in Pharmacology, 2019
The growing interest in testosterone's effects on men's social behaviors, in particular aggressive, risk-taking, or status maintenance behaviors, is accompanied by a paucity of dose-dependent pharmacokinetic data. Examining the neurophysiological effects
Andrei A. Puiu, Andrei A. Puiu, Sina Radke, Mikhail Votinov, Mikhail Votinov, Ute Habel, Ute Habel, Beate Herpertz-Dahlmann, Bruce Turetsky, Kerstin Konrad, Kerstin Konrad   +10 more
doaj   +1 more source

Testosterone concentrations and prescription patterns of 1% testosterone gel in transgender and gender diverse individuals

Therapeutic Advances in Endocrinology and Metabolism, 2022
Background: Masculinising hormone therapy with testosterone is used to align an individual’s physical characteristics with their gender identity. Standard testosterone doses and formulations recommended for hypogonadal cisgender men are typically ...
Brendan J. Nolan, Sav Zwickl, Alex F. Q. Wong, Peter Locke, Satu Simpson, Ling Li, Jeffrey D. Zajac, Ada S. Cheung   +7 more
doaj   +1 more source

Fetal testosterone and autistic traits [PDF]

, 2009
Studies of amniotic testosterone in humans suggest that fetal testosterone (fT) is related to specific (but not all) sexually dimorphic aspects of cognition and behaviour.
Kevin Taylor, Simon Baron‐Cohen, Bonnie Auyeung, Rebecca Knickmeyer, Knickmeyer, Rebecca, Ashwin, Emma, Auyeung, Bonnie; id_orcid, Gerald Hackett, Taylor, Kevin, Hackett, Gerald, Emma Ashwin, Baron-Cohen, Simon   +11 more
core   +1 more source

Transcriptional Profiling of Luteinizing Hormone Receptor-Deficient Mice Before and after Testosterone Treatment Provides Insight into the Hormonal Control of Postnatal Testicular Development and Leydig Cell Differentiation [PDF]

, 2010
Luteinizing hormone (LH) is a key regulator of male fertility through its effects on testosterone secretion by Leydig cells. Transcriptional control of this is, however, currently poorly understood.
Affara, Nabeel, Abel, M, Ellis, Peter J.I., Dunmore, B., Bauer, Johann W., Griffin, Darren K.   +5 more
core   +1 more source

Fabrication of silastic testosterone enanthate implants to achieve virilizing levels of serum testosterone in swine

MethodsX
The aim of this study was to create a continuous drug delivery system that would yield serum testosterone levels in sexually mature, female pigs consistent with serum testosterone levels of human transgender men.
Nirvana Mahabir, Annie E. Newell-Fugate
doaj   +1 more source

Testes size, testosterone production and reproductive behaviour in a natural mammalian mating system [PDF]

, 2012
1. Testosterone (T) is a key mediator in the expression of numerous morphological and behavioural traits in mammals, but the factors underlying individual variation in circulating T levels are poorly understood. 2.
Monfort, Steven L., Stevenson, Ian R., Preston, Brian T., Lincoln, Gerald A., Pilkington, Jill G., Wilson, Kenneth   +5 more
core   +5 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Testosterone for schizophrenia

Cochrane Database of Systematic Reviews, 2006
Recently, sex hormones such as estrogens and testosterone or its derivatives have been the focus of interest for treatment of persistent symptoms associated with schizophrenia.To review the effects of dehydroepiandrosterone (DHEA)/testosterone as adjunctive therapy to standard antipsychotic drugs.We searched the Cochrane Schizophrenia Group Trials ...
Elias, Alby, Kumar, Ajit
openaire   +2 more sources