Results 21 to 30 of about 144,614 (267)

Safety Aspects and Rational Use of Testosterone Undecanoate in the Treatment of Testosterone Deficiency: Clinical Insights

Drug, Healthcare and Patient Safety, 2023
Katherine Campbell,1 Akhil Muthigi,1 Armin Ghomeshi,2 Kyle Schuppe,3 Max D Sandler,4 Ranjith Ramasamy1 1Desai Sethi Urology Institute, University of Miami, Miami, Fl, 33136, USA; 2Herbert Wertheim College of Medicine, Florida International University ...
Campbell K, Muthigi A, Ghomeshi A, Schuppe K, Sandler MD, Ramasamy R   +5 more
doaj  

Testosterone, testosterone therapy and prostate cancer

The Aging Male, 2019
With prostate cancer not observed in eunuchs and total androgen suppression by castration an effective first-line treatment for advanced prostate cancer, the dramatic regression seen in tumour symptoms after castration, lead to the theory that high levels of circulating androgens were a risk factor for prostate cancer.
A, Yassin, K, AlRumaihi, R, Alzubaidi, S, Alkadhi, A, Al Ansari   +4 more
openaire   +2 more sources

Free Testosterone Reflects Metabolic as well as Ovarian Disturbances in Subfertile Oligomenorrheic Women

International Journal of Endocrinology, 2018
Background. Diagnosing polycystic ovary syndrome (PCOS) is based on ovulatory dysfunction, ovarian ultrasound data, and androgen excess. Total testosterone is frequently used to identify androgen excess, but testosterone is mainly bound to sex hormone ...
L. Antonio, S. Pauwels, M. R. Laurent, D. Vanschoubroeck, I. Jans, J. Billen, F. Claessens, B. Decallonne, Diane De Neubourg, P. Vermeersch, D. Vanderschueren   +10 more
doaj   +1 more source

Testosterone concentrations and prescription patterns of 1% testosterone gel in transgender and gender diverse individuals

Therapeutic Advances in Endocrinology and Metabolism, 2022
Background: Masculinising hormone therapy with testosterone is used to align an individual’s physical characteristics with their gender identity. Standard testosterone doses and formulations recommended for hypogonadal cisgender men are typically ...
Brendan J. Nolan, Sav Zwickl, Alex F. Q. Wong, Peter Locke, Satu Simpson, Ling Li, Jeffrey D. Zajac, Ada S. Cheung   +7 more
doaj   +1 more source

Testosterone trajectories and reference ranges in a large longitudinal sample of male adolescents.

PLoS ONE, 2014
PurposePubertal dynamics plays an important role in physical and psychological development of children and adolescents. We aim to provide reference ranges of plasma testosterone in a large longitudinal sample.
Ammar Khairullah, Laura Cousino Klein, Suzanne M Ingle, Margaret T May, Courtney A Whetzel, Elizabeth J Susman, Tomáš Paus   +6 more
doaj   +1 more source

Serum Testosterone and Cortisol Concentrations After Single-Dose Administration of 100-Mg Transdermal Testosterone in Healthy Men

Frontiers in Pharmacology, 2019
The growing interest in testosterone's effects on men's social behaviors, in particular aggressive, risk-taking, or status maintenance behaviors, is accompanied by a paucity of dose-dependent pharmacokinetic data. Examining the neurophysiological effects
Andrei A. Puiu, Andrei A. Puiu, Sina Radke, Mikhail Votinov, Mikhail Votinov, Ute Habel, Ute Habel, Beate Herpertz-Dahlmann, Bruce Turetsky, Kerstin Konrad, Kerstin Konrad   +10 more
doaj   +1 more source

Fabrication of silastic testosterone enanthate implants to achieve virilizing levels of serum testosterone in swine

MethodsX
The aim of this study was to create a continuous drug delivery system that would yield serum testosterone levels in sexually mature, female pigs consistent with serum testosterone levels of human transgender men.
Nirvana Mahabir, Annie E. Newell-Fugate
doaj   +1 more source

Testosterone protects mice against zika virus infection and suppresses the inflammatory response in the brain

iScience, 2022
Summary: Testosterone is essential to human growth and development as well as immune regulation. Zika virus (ZIKV), an emerging arbovirus associated with neurological complications including neuroinflammation, can also cause testicular damage and ...
Bohan Zheng, Jiajun Sun, Haoran Luo, Ling’en Yang, Qi Li, Luping Zhang, Youhui Si, Shengbo Cao, Jing Ye   +8 more
doaj   +1 more source

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

Arthritis Care &Research, EarlyView.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown   +4 more
wiley   +1 more source

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

Advanced Healthcare Materials, EarlyView.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone, Giorgia Imparato, Chiara Ausilio, Valentina Mollo, Paolo Antonio Netti   +4 more
wiley   +1 more source