Results 1 to 10 of about 5,278 (159)

Safety of equine tetanus antitoxin for prophylactic use in Ethiopia: a retrospective multi-center study [PDF]

Tropical Medicine and Health, 2023
Background Tetanus remains a severe life-threatening infectious disease and neurological disorder in many parts of the world, where immunization programs are suboptimal.
Michele Joseph, Yimtubeznash Woldeamanuel, Girmay Medhin, Tsegahun Manyazewal, Abebaw Fekadu, Eyasu Makonnen   +5 more
doaj   +2 more sources

Complete Neutralization of Tetanus Neurotoxin by Alpaca-Derived Trivalent Nanobodies Aimed at Veterinary Medical Applications [PDF]

Veterinary Sciences
Tetanus is a zoonotic disease posing significant threats to both humans and animals, particularly horses, sheep, and ruminants. Current antitoxin therapies rely on animal-derived immunoglobulins, presenting challenges including animal welfare concerns ...
Chiyomi Sakamoto, Chie Shitada, Norihiko Kiyose, Nobuo Miyazaki, Sena Kamesawa, Hiroshi Morioka, Kazunori Morokuma, Kazuhiko Tomokiyo, Motohide Takahashi   +8 more
doaj   +2 more sources

Determination of low tetanus or diphtheria antitoxin titers in sera by a toxin neutralization assay and a modified toxin-binding inhibition test [PDF]

Brazilian Journal of Medical and Biological Research, 2007
A method for the screening of tetanus and diphtheria antibodies in serum using anatoxin (inactivated toxin) instead of toxin was developed as an alternative to the in vivo toxin neutralization assay based on the toxin-binding inhibition test (TOBI test).
M.H. Sonobe, A.G. Trezena, F.B. Guilhen, V.L. Takano, F. Fratelli, D. Sakauchi, J.F. Morais, S.M.A. Prado, H.G. Higashi   +8 more
doaj   +2 more sources

Adjustments for oral fluid quality and collection methods improve prediction of circulating tetanus antitoxin: Approaches for correcting antibody concentrations detected in a non-invasive specimen.

Vaccine, 2021
Garrison-Desany H, Ochieng BO, Odiere MR, Kuo H, Gibson DG, Were J, Kagucia EW, Pasetti MF, Kim H, Reymann M, O'Brien K, Hayford K.   +11 more
europepmc   +2 more sources

Evaluating the effect of equine tetanus antitoxin on mortality rates of dogs affected by tetanus

Veterinary Evidence
PICO Question In dogs with tetanus, does administering the equine tetanus antitoxin compared to not administering the antitoxin reduce mortality rates?   Clinical bottom line Category of research Treatment.
Berry Wong
doaj   +3 more sources

Passive Immunisation in the Treatment of Infectious Diseases Related to Highly Potent Bacterial Toxins [PDF]

Biomedicines
The discovery of microbial toxins as the primary factors responsible for disease manifestations and the discovery that these toxins could be neutralised by antitoxins are linked to the birth of immunology. In the late 19th century, the serum or plasma of
Marta Prygiel, Ewa Mosiej, Karol Wdowiak, Aleksandra Anna Zasada   +3 more
doaj   +2 more sources

Factors Influencing the Length of Emergency Intensive Care Unit Stay in Adult Tetanus Patients [PDF]

International Journal of General Medicine
Ji Xu,1 Ying Wang,2 Guoqing Huang,1 Liping Zhou,1 Xiaoye Mo,1 Ning Yang,1 Ping Wu,1 Shanshan Hu,1 Changshou She1 1Department of Emergency Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, People’s Republic of China; 2Xiangya Medical ...
Xu J, Wang Y, Huang G, Zhou L, Mo X, Yang N, Wu P, Hu S, She C   +8 more
doaj   +2 more sources

Tetanus Vaccination in Agricultural Workers: A Retrospective Study on Seroprevalence over 10 Years [PDF]

Vaccines
Background/Objectives: Tetanus is a serious, non-contagious infection caused by Clostridium tetani, which remains a global health threat despite the availability of an effective vaccine. The current state of immunization for agricultural workers in Italy
Ermanno Vitale, Veronica Filetti, Giorgio Bertolazzi, Gabriele Giorgianni, Nektaria Zagorianakou, Andrea Marino, Massimiliano Esposito, Vincenzo Restivo, Serena Matera, Venerando Rapisarda, Luigi Cirrincione   +10 more
doaj   +2 more sources

Tetanus with Low back and Knee Pain, Abdominal Distension and Constipation as Initial Presentations: Report of a Deaf and Mute Case and Literature Review [PDF]

Zhongguo quanke yixue, 2023
Tetanus is a life-threatening and fatal disease that can be prevented by vaccination. The diagnosis of tetanus is based solely on medical history and clinical symptoms and is very prone to misdiagnosis, undertreatment, and delayed treatment.
BAO Yiru, BAO Shouqian, ZHANG Zhaohui, ZHANG Yinchuan
doaj   +1 more source

Can the Problem of Uncontrolled and Unnecessary Tetanus Vaccination of Workers Working in Industrial Workplaces Be Solved?

Mediterranean Journal of Infection, Microbes and Antimicrobials, 2021
Introduction: Since antibodies against tetanus decrease over time and disappear completely, especially in older ages, it is recommended to give tetanus booster every 10 years for adults. However, in some risky occupational groups, tetanus vaccination can
Selma TOSUN, Halil ERKAN, Hülya ÖZKAN ÖZDEMİR, Alpay ARI, Mustafa APAK   +4 more
doaj   +1 more source