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Safety of equine tetanus antitoxin for prophylactic use in Ethiopia: a retrospective multi-center study [PDF]

open access: yesTropical Medicine and Health, 2023
Background Tetanus remains a severe life-threatening infectious disease and neurological disorder in many parts of the world, where immunization programs are suboptimal.
Michele Joseph   +5 more
doaj   +2 more sources

Mortality and Associated Factors Among Adult Tetanus Patients Admitted at Public Hospitals in Bahir Dar City, Ethiopia: A Cross‐Sectional Study [PDF]

open access: yesHealth Science Reports
Background and Aims Tetanus, caused by Clostridium tetani, results in rigor spasms and remains as major cause of mortality in areas with poor vaccination and sanitation.
Mulugeta Tesfaw   +3 more
doaj   +2 more sources

Complete Neutralization of Tetanus Neurotoxin by Alpaca-Derived Trivalent Nanobodies Aimed at Veterinary Medical Applications [PDF]

open access: yesVeterinary Sciences
Tetanus is a zoonotic disease posing significant threats to both humans and animals, particularly horses, sheep, and ruminants. Current antitoxin therapies rely on animal-derived immunoglobulins, presenting challenges including animal welfare concerns ...
Chiyomi Sakamoto   +8 more
doaj   +2 more sources

Generalized Tetanus in an Unvaccinated Adolescent: A Case Report on Successful Management in a Resource-Limited Setting [PDF]

open access: yesInternational Medical Case Reports Journal
Abdirahin Mohamed Abdulkadir,1 Ismail Mahad Abdullahi,1 Fartun Abdullahi Hassan,2 Abdullahi Hassan Elmi3 1Department of Emergency Medicine, Dr. Sumait Hospitals, Faculty of Medicine and Health Sciences, SIMAD University, Mogadishu, Somalia; 2Department ...
Abdulkadir AM   +3 more
doaj   +2 more sources

Factors Influencing the Length of Emergency Intensive Care Unit Stay in Adult Tetanus Patients [PDF]

open access: yesInternational Journal of General Medicine
Ji Xu,1 Ying Wang,2 Guoqing Huang,1 Liping Zhou,1 Xiaoye Mo,1 Ning Yang,1 Ping Wu,1 Shanshan Hu,1 Changshou She1 1Department of Emergency Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, People’s Republic of China; 2Xiangya Medical ...
Xu J   +8 more
doaj   +2 more sources

Passive Immunisation in the Treatment of Infectious Diseases Related to Highly Potent Bacterial Toxins [PDF]

open access: yesBiomedicines
The discovery of microbial toxins as the primary factors responsible for disease manifestations and the discovery that these toxins could be neutralised by antitoxins are linked to the birth of immunology. In the late 19th century, the serum or plasma of
Marta Prygiel   +3 more
doaj   +2 more sources

Tetanus Vaccination in Agricultural Workers: A Retrospective Study on Seroprevalence over 10 Years [PDF]

open access: yesVaccines
Background/Objectives: Tetanus is a serious, non-contagious infection caused by Clostridium tetani, which remains a global health threat despite the availability of an effective vaccine. The current state of immunization for agricultural workers in Italy
Ermanno Vitale   +10 more
doaj   +2 more sources

Tetanus with Low back and Knee Pain, Abdominal Distension and Constipation as Initial Presentations: Report of a Deaf and Mute Case and Literature Review [PDF]

open access: yesZhongguo quanke yixue, 2023
Tetanus is a life-threatening and fatal disease that can be prevented by vaccination. The diagnosis of tetanus is based solely on medical history and clinical symptoms and is very prone to misdiagnosis, undertreatment, and delayed treatment.
BAO Yiru, BAO Shouqian, ZHANG Zhaohui, ZHANG Yinchuan
doaj   +1 more source

Release of vasopressin from isolated permeabilized neurosecretory nerve terminals is blocked by the light chain of botulinum A toxin [PDF]

open access: yes, 1990
The intracellular action on exocytosis of botulinim A toxin and constituent chains was studied using permeabilized isolated nerve endings from the rat neural lobe. The release of the neuropeptide vasopressin was measured by radioimmunoassay.
Ahnert-Hilger, G.   +4 more
core   +6 more sources

Can the Problem of Uncontrolled and Unnecessary Tetanus Vaccination of Workers Working in Industrial Workplaces Be Solved?

open access: yesMediterranean Journal of Infection, Microbes and Antimicrobials, 2021
Introduction: Since antibodies against tetanus decrease over time and disappear completely, especially in older ages, it is recommended to give tetanus booster every 10 years for adults. However, in some risky occupational groups, tetanus vaccination can
Selma TOSUN   +4 more
doaj   +1 more source

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