Results 71 to 80 of about 8,283 (248)
The challenges and breakthroughs in the development of diagnostic monoclonal antibodies
VIEW, Volume 5, Issue 4, August 2024.This study has systematically organized the discovery of antibodies into three stages and analyzed the advantages and disadvantages of each stage. Meanwhile, This study deeply analyzes challenges, proposing innovative strategies for the next generation of diagnostic antibody development. Aimed at moving closer to the gold standard of antibody discovery,
Jing Wang +21 more
wiley +1 more source
Evaluating the effect of equine tetanus antitoxin on mortality rates of dogs affected by tetanus
Veterinary EvidencePICO Question In dogs with tetanus, does administering the equine tetanus antitoxin compared to not administering the antitoxin reduce mortality rates? Clinical bottom line Category of research Treatment.
Berry Wong
doaj +1 more source
Frontiers in Veterinary Science, 2023 ObjectiveTetanus is a severe neurologic disease caused by Clostridium tetani, resulting in spastic paralysis. Canine tetanus is associated with serious complications such as aspiration and a high mortality rate of up to 50%.Materials and methodsMedical ...
Stefanie Dörfelt +6 more
doaj +1 more source
Journal of Veterinary Internal Medicine, Volume 38, Issue 4, Page 2373-2379, July/August 2024.Abstract Background Equine parvovirus hepatitis (EqPV‐H) can cause Theiler's disease and subclinical hepatitis in horses. Objectives Assess the frequency of subclinical EqPV‐H infection in hospitalized horses and to study viral transmission by investigating potential shedding routes.
Dilara Lale +7 more
wiley +1 more source
What is the role of microbial biotechnology and genetic engineering in medicine?
MicrobiologyOpen, Volume 13, Issue 2, April 2024.Microbial biotechnology, the technological application of microorganisms, has been instrumental in producing significant natural bioactive products. These include antibiotics, antifungals, anticancer drugs, antiparasitics, antivirals, immunosuppressants, toxoid vaccines, and therapeutic enzymes.
Fernando Santos‐Beneit
wiley +1 more source
A Targeted Therapeutic Rescues Botulinum Toxin-A Poisoned Neurons [PDF]
, 2008 Botulinum neurotoxin (BoNT), a Category A biothreat agent, is the most potent poison known to mankind. Currently no antidote is available to rescue poisoned synapses.
Bal Ram Singh +6 more
core +1 more source
A CASE OF TETANUS SUCCESSFULLY TREATED BY TETANUS ANTITOXIN. [PDF]
The Lancet, 1897 n ...
openaire +3 more sources
The light chain of tetanus toxin inhibits calcium-dependent vasopressin release from permeabilized nerve endings [PDF]
, 1992 The effects of tetanus toxin and its light and heavy chain subunits on vasopressin release were investigated in digitonin-permeabilized neurosecretory nerve terminals isolated from the neural lobe of the rat pituitary gland.
Ahnert-Hilger, G. +5 more
core +1 more source
Zoonoses and Public Health, Volume 71, Issue 2, Page 127-135, March 2024.Abstract Aims Corynebacterium diphtheriae and Corynebacterium ulcerans, when producing toxin, are the cause of diphtheria, a potentially life‐threatening illness in humans. Horses (Equus ferus caballus) are known to be susceptible to infection that may manifest clinically on rare occasions.
Thomas Sven Christer Grönthal +11 more
wiley +1 more source
Tetanus and diphtheria immunity in adolescents from São Paulo, Brazil [PDF]
, 2007 Tetanus and diphtheria vaccines are of special concern in adolescents because boosters are necessary for adequate maintenance of protection and are often omitted.
De Moraes-Pinto, Maria Isabel [UNIFESP] +2 more
core +2 more sources