Results 71 to 80 of about 158,757 (218)

Of mice and men—The emerging oral–gut–brain axis of health and disease

Periodontology 2000, EarlyView.
Abstract Objectives Oral health's inextricable links to systemic health are highlighted by the emerging oral–gut–brain axis and other well‐known axes. There is growing evidence of a complex oral–gut–brain axis linking mouth and gut microbiomes with the central nervous system.
Yvonne L. Hernandez‐Kapila, Daniel J. Weisenberger   +1 more
wiley   +1 more source

A glycoconjugate of Haemophilus influenzae Type b capsular polysaccharide with tetanus toxoid protein: hydrodynamic properties mainly influenced by the carbohydrate [PDF]

, 2016
Three important physical properties which may affect the performance of glycoconjugate vaccines against serious disease are molar mass (molecular weight), heterogeneity (polydispersity), and conformational flexibility in solution.
Harding, Stephen E., Conrath, K., Almuntari, F., Almutairi, Fahad M., Duvivier, Pierre, Harding, S. E., Adams, G. G., Morris, Gordon, Duvivier, P., Morris, Gordon A., Abdelhameed, Ali Saber, Adams, Gary G., Abdelhameed, A. S., Conrath, Karel, GSK Vaccines, Rue de l’Institut 89, B-1330 Rixensart, Belgium   +14 more
core   +1 more source

The Transglutaminase Hypothesis For the Action of Tetanus Toxin

, 1993
Tetanus toxin potently and almost irreversibly inhibits the release of neurotransmitters from nerve terminals. The toxin binds to and activates transglutaminase, a Ca2+-dependent enzyme that can form stable crosslinks between substrate proteins ...
F. VALTORTA, A. LUINI, F. FACCHIANO, BENFENATI, FABIO   +3 more
core   +2 more sources

Characterization of the Immune Response after Oral Cholera Vaccination (OCV) and Effects of Mycophenolate Mofetil on Priming of this Immune Response—A Randomized, Placebo‐Controlled Trial

Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 1049-1056, October 2026.
Mycophenolate mofetil (MMF) is an immunosuppressive drug widely used by solid organ transplant recipients. Although it is known that MMF suppresses immune responses, its exact effects on specific vaccinations have not been investigated yet. Mucosal vaccinations are increasingly used, such as a cholera vaccination consisting of two oral immunizations ...
Boukje C. Eveleens Maarse, Aliede E. in 't Veld, Hendrika W. Grievink, Manon A.A. Jansen, Matthijs Moerland   +4 more
wiley   +1 more source

Abortion—A brief description of the evolution of methods

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 10, Page 1898-1903, October 2026.
Termination of pregnancy is not a “modern” societal issue, but one that has been afforded to women, albeit with varying degrees of success, over many centuries. Methods have evolved which have increased the availability, effectiveness, and safety of abortion, while substantially reducing associated morbidity.
Laura Slade, Andrea Deussen, Jodie Dodd
wiley   +1 more source

Detección inmunoenzimática de la toxina de la bacteria Clostridium tetani: una alternativa a las pruebas biológicas con ratones

Revista de Biología Tropical, 2006
Immunoenzimatic detection of the Clostridium tetani bacterial toxin: an alternative to mice bioassays. Cell-free extracts from 20 strains of Clostridium tetani isolated from soil samples, were tested for tetanus toxin production using an enzyme ...
Fernando Chaves, Guillermo León, Francisco Hernández-Chavarría   +2 more
doaj  

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

Angewandte Chemie International Edition, Volume 65, Issue 39, 21 September 2026.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source

Loss of Neutrophils and SLPI Reshapes Early Mucosal Inflammatory Responses During Intranasal Vaccination

European Journal of Immunology, Volume 56, Issue 9, September 2026.
Intranasal vaccination induces pulmonary neutrophil accumulation and SLPI release, accompanied by changes in soluble mediators associated with tissue remodelling, coagulation, and total IgA. ABSTRACT Vaccines delivered via the nasal route have attracted increasing attention for their capacity to engage the mucosal immune system at the primary site of ...
Oktawia Osiecka, Mariia Tyshchenko, Ivan Sinkevich, Natalia Pocałuń, Joanna Cichy, Jakub M. Kwiecinski, Ewa Oleszycka, Mieszko M. Wilk   +7 more
wiley   +1 more source

THE EFFECT OF KETAMINE AND ITS COMBINATION WITH INDOL-2-CARBOXYLIC ACID AND CAROVERINE ON SURVIVAL TIME OF MICE WITH EXPERIMENTAL TETANUS

Veterinaria, 2017
Tetanus, also known as lockjaw, is a very dangerous infectious acute, usually afebrile disease characterized by muscle spasms, affecting humans and various animal species. The causative agent of the disease is bacteria Clostridium tetani.
Indira Mujezinović, Ahmed Smajlović
doaj  

Characterization of a Highly Toxigenic Clostridium tetani Strain from a Calf’s Castration Site

Veterinary Sciences
Background: This case report describes a calf that underwent castration at a Japanese livestock farm and subsequently died after developing clinical signs of tetanus, including muscle rigidity and difficulty standing.
Chie Shitada, Mayu Ohira, Mika Sekiguchi, Tomoko Koda, Motohide Takahashi, Makoto Kuroda   +5 more
doaj   +1 more source