Results 51 to 60 of about 16,236 (178)

Inducing Antigen‐Specific and Functional Immune Responses in Mice Toward Bovine Herpesvirus 1 and Bovine Respiratory Syncytial Virus by Chimeric Peptides Delivered by Bovine Herpesvirus 4‐Based Vector

Immunology, Volume 179, Issue 1, Page 54-71, September 2026.
Bovine Alphaherpesvirus 1 (BoHV‐1) and Bovine respiratory syncytial virus (BRSV) are major drivers of respiratory disease in cattle. (A) To target both pathogens, two chimeric antigens—membrane‐linked and secreted—combining BoHV‐1 glycoprotein D and BRSV fusion glycoprotein were designed and expressed using recombinant BoHV‐4‐based vectors.
Antonino Di Lorenzo, Sergio Minesso, Chiara Cossu, Valentina Franceschi, Elisabetta Bolli, Vittorio Madia, Laura Conti, Gaetano Donofrio   +7 more
wiley   +1 more source

Neonatal Bloodstream Infections: A Narrative Review on Diagnostic and Therapeutic Challenges and Prospects in Developing Countries

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Bloodstream infections (BSIs) pose a significant global health challenge, particularly in developing countries. Neonates are highly vulnerable due to underdeveloped immune systems and immature physical barriers, a risk amplified by poor hygiene and limited healthcare access in low‐ and middle‐income countries (LMICs), leading to an ...
Alex Odoom, Abdul‐Halim Osman, Onyansaniba K. Ntim, Fleischer C. N. Kotey, Eric S. Donkor   +4 more
wiley   +1 more source

More than a Toxin: Protein Inventory of Clostridium tetani Toxoid Vaccines

Proteomes, 2019
Clostridium tetani is the etiological agent of tetanus, a life-threatening bacterial infection. The most efficient protection strategy against tetanus is a vaccination with the C.
Jens Möller, Max Edmund Kraner, Andreas Burkovski   +2 more
doaj   +1 more source

Flashing third eyelids and other involuntary facial movements in tetanus in four dogs

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract This study describes four dogs with tetanus that presented with ‘flashing third eyelids’ and other involuntary facial movements. Flashing of the third eyelids reflects the intermittent involuntary bilateral eyeball retraction accompanied by passive movements of the nictitating membranes. Four dogs presented with ‘flashing third eyelids’ either
Theofanis Liatis, Dakir Polidoro, Eleftheria Skovola, Clara Mattavelli, Eric N. Glass   +4 more
wiley   +1 more source

CLINICO–Demographic Profile and Outcomes of Hospitalised Children With Diphtheria in A Tertiary Care Hospital of Peshawar

Acta Paediatrica, Volume 115, Issue 8, Page 1646-1653, August 2026.
ABSTRACT Aim To determine the clinico‐demographic profile and predictors of mortality in hospitalised children with diphtheria. Methods This retrospective cohort study included 202 children aged 5–16 years diagnosed with diphtheria per WHO criteria at Lady Reading Hospital, Peshawar, from January 2023 to December 2024. Data on demographics, vaccination
Amir Muhammad, Ashfaq Ahmed, Waqas Naseem, Ale Azad Othman, Mohsin Hassan, Lyaba Atta, Muhammad Tahir   +6 more
wiley   +1 more source

Patient‐Derived IgG Epitope Mapping of Bet v 1 Reveals Hypoallergenic Peptide Candidates for Safe and Next‐Generation Allergen Immunotherapy

Clinical &Experimental Allergy, Volume 56, Issue 8, Page 881-892, August 2026.
Mapping IgG epitopes of the major birch allergen Bet v 1 identified patient‐derived, hypoallergenic peptides that did not trigger degranulation. These findings support a novel, safer approach for peptide‐based allergen immunotherapy that leverages naturally induced IgG specificities from allergic individuals. ABSTRACT Background Allergen immunotherapy (
Lara Šošić, Marta Paolucci, Alessandro Streuli, David A. Melillo, Tianchi Jiang, Raffaela Campana, Claudia C. V. Lang, Thomas M. Kündig, Christian Steuer, Klaus Eyer, Pål Johansen   +10 more
wiley   +1 more source

Detección inmunoenzimática de la toxina de la bacteria Clostridium tetani: una alternativa a las pruebas biológicas con ratones

Revista de Biología Tropical, 2006
Immunoenzimatic detection of the Clostridium tetani bacterial toxin: an alternative to mice bioassays. Cell-free extracts from 20 strains of Clostridium tetani isolated from soil samples, were tested for tetanus toxin production using an enzyme ...
Fernando Chaves, Guillermo León, Francisco Hernández-Chavarría   +2 more
doaj  

GC B Cells, Tfh Cells, and Influenza bnAbs: Insights for Improving Universal Vaccine Design

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Antibodies are crucial for providing protection against influenza virus infection; however, protective humoral immunity is limited by antigenic drift and shift. Hence, the discovery of broadly neutralizing antibodies (bnAbs) targeting conserved epitopes on hemagglutinin protein evokes the hope of developing a universal influenza vaccine ...
Takeshi Inoue, Wataru Ise, Tomohiro Kurosaki   +2 more
wiley   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

THE EFFECT OF KETAMINE AND ITS COMBINATION WITH INDOL-2-CARBOXYLIC ACID AND CAROVERINE ON SURVIVAL TIME OF MICE WITH EXPERIMENTAL TETANUS

Veterinaria, 2017
Tetanus, also known as lockjaw, is a very dangerous infectious acute, usually afebrile disease characterized by muscle spasms, affecting humans and various animal species. The causative agent of the disease is bacteria Clostridium tetani.
Indira Mujezinović, Ahmed Smajlović
doaj