Results 41 to 50 of about 158,757 (218)
Water‐Soluble, Enzyme‐Degradable, and Hydrolyzable STAR Particles for Enhanced Drug Delivery to Skin
Advanced Healthcare Materials, EarlyView.Biodegradable polymer STAR particles fabricated from water‐soluble, enzyme‐degradable, and hydrolyzable materials significantly enhance intradermal drug delivery. By replacing conventional non‐biodegradable materials, these STAR particles address environmental and safety concerns while expanding the potential of skin‐based drug delivery technologies ...
Aydin Sadeqi +2 more
wiley +1 more source
Neurobiology of Disease, 2001 The effect of pretreatment with either tetanus toxin (in ventral hippocampus) or kainic acid (into dorsal hippocampus, with or without suppression of seizures by phenobarbital) on the subsequent development of epilepsy in rats injected with tetanus toxin
J. Mellanby, A.J. Milward
doaj +1 more source
Advanced Science, EarlyView.Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke +10 more
wiley +1 more source
Neutralization of Lethal Potency of Tetanus Toxin using Phage Display Produced scFv Antibody [PDF]
, 2021 Background and Aim: Phage display technology provides a new approach for making human antibody fragments that could be applicable in passive immune therapy.
Abbasi, Ebrahim +2 more
core +1 more source
Optimization of human TAT-Fab antibody expression and its bioactivity assay
浙江大学学报. 农业与生命科学版, 2007 In order to establish high effective expression system for human TAT-Fab antibody with protective activity, the induction conditions for the expression of TAT-Fab antibody in E.
WANG Qun +4 more
doaj +1 more source
EAR PIERCING: A GATEWAY TO TETANUS
Pakistan Armed Forces Medical Journal, 2022 Tetanus is initiated by the release of neurotoxins. The progressive paralysis of several muscles is due to contamination of the wound by the toxin.
Hassan Mumtaz +4 more
doaj +1 more source
The interaction of tetanus toxin and antitoxin [PDF]
Journal of Hygiene, 1953 Tetanus antitoxic horse sera were fractionated with sodium sulphate and by electrophoretic separation. The activity of the native serum and of fractions was determinedin vivoin the mouse and guinea-pig andin vitroby the flocculation method. All the sera and fractions showed several zones of flocculation.
B, CINADER, B, WEITZ
openaire +2 more sources
Delineation of several DR-restricted tetanus toxin T cell epitopes [PDF]
, 1989 We have characterized five human T cell clones specific for tetanus toxin. The combination of different techniques allowed us to precisely map two T cell epitopes within fragments 830-843 and 1273-1284 of tetanus toxin, as formally demonstrated by the ...
Widmann, C. +5 more
core +2 more sources
Tetanus in Animals — Summary of Knowledge
Folia Veterinaria, 2020 Tetanus is a neurologic non-transmissible disease (often fatal) of humans and other animals with a worldwide occurrence. Clostridium tetani is the spore producing bacillus which causes the bacterial disease.
Malinovská Z., Čonková E., Váczi P.
doaj +1 more source
Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges
Epilepsia Open, EarlyView.Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus +7 more
wiley +1 more source