Results 31 to 40 of about 18,141 (217)
Release of vasopressin from isolated permeabilized neurosecretory nerve terminals is blocked by the light chain of botulinum A toxin [PDF]
, 1990 The intracellular action on exocytosis of botulinim A toxin and constituent chains was studied using permeabilized isolated nerve endings from the rat neural lobe. The release of the neuropeptide vasopressin was measured by radioimmunoassay.
Weller, U. +4 more
core +1 more source
Studies on Tetanus Toxin and Toxoid IV. Interaction of Formaldehyde with Tetanus Toxin [PDF]
Australian Journal of Biological Sciences, 1969 The binding of formaldehyde with tetanus toxin under mild detoxificatIOn conditions (0 ·1M phosphate buffer, pH 7· 0, O· 005-0· 06M HCHO, 20-37°C) has been studied quantitatively by using [14C]formaldehyde. When detoxification was followed with time (0· 005M HCHO, 37°C) the toxin showed a characteristic immediate drop in lethality (~80%), followed by a
D J, Dawson, C M, Mauritzen
openaire +2 more sources
The light chain but not the heavy chain of botulinum A toxin inhibits exocytosis from permeabilized adrenal chromaffin cells [PDF]
, 1989 The heavy and light chains of botulinum A toxin were separated by anion exchange chromatography. Their intracellular actions were studied using bovine adrenal chromaffin cells permeabilized with streptolysin O.
M. Gratzl +10 more
core +1 more source
The interaction of tetanus toxin and antitoxin [PDF]
Journal of Hygiene, 1953 Tetanus antitoxic horse sera were fractionated with sodium sulphate and by electrophoretic separation. The activity of the native serum and of fractions was determinedin vivoin the mouse and guinea-pig andin vitroby the flocculation method. All the sera and fractions showed several zones of flocculation.
B, CINADER, B, WEITZ
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Novel Small Molecule Inhibitors That Prevent the Neuroparalysis of Tetanus Neurotoxin
Pharmaceuticals, 2021 Tetanus neurotoxin (TeNT) is a protein exotoxin produced by Clostridium tetani that causes the deadly spastic neuroparalysis of tetanus. It consists of a metalloprotease light chain and of a heavy chain linked via a disulphide bond.
Giulia Zanetti +5 more
doaj +1 more source
The effect of tetanus toxin in the goldfish [PDF]
The Journal of Physiology, 1971 1. The effects of tetanus toxin have been investigated both on central nervous and peripheral neuromuscular systems of goldfish.2. Tetanus toxin kills goldfish when administered in minute doses. The lethal effect is temperature dependent. Unlike mammals, in which tetanus toxin produces spastic paralysis and convulsions, the tetanus‐intoxicated goldfish
J, Diamond, J, Mellanby
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Molecular Aspects of Secretory Granule Exocytosis by Neurons and Endocrine Cells [PDF]
, 1994 Neuronal communication and endocrine signaling are fundamental for integrating the function of tissues and cells in the body. Hormones released by endocrine cells are transported to the target cells through the circulation.
MANFRED GRATZL, Gratzl, Manfred
core +1 more source
Infection in a Geriatric Patient: Do Not Let Your Guard Off! [PDF]
Annals of Geriatric Medicine and Research, 2023 Tetanus is an infectious disease caused by Clostridium tetani toxin. Although easily preventable through vaccination, over 73,000 new infections and 35,000 deaths due to tetanus occurred worldwide in 2019, with higher rates in countries with healthcare ...
Alessandra Piscitelli +9 more
doaj +1 more source
International Journal of Emergency Medicine, 2021 Background Tetanus is a rare disease caused by Clostridium tetani, which produces tetanolysin and tetanospasmin. In 2018, there were only approximately ten tetanus cases reported in Indonesia.
Dzulfikar D. L. Hakim +6 more
doaj +1 more source
From Bacterial Poisons to Toxins: The Early Works of Pasteurians
Toxins, 2022 We review some of the precursor works of the Pasteurians in the field of bacterial toxins. The word “toxin” was coined in 1888 by Ludwig Brieger to qualify different types of poison released by bacteria.
Jean-Marc Cavaillon
doaj +1 more source