Results 11 to 20 of about 16,236 (178)
Evaluation of Potency on Diphtheria and Tetanus Toxoid for Adult Vaccines by In Vivo Toxin Neutralization Assay Using National Reference Standards [PDF]
Osong Public Health and Research Perspectives, 2018 Objectives Vaccinations against diphtheria and tetanus are essential in providing immunity against these bacterial infections. The potency of diphtheria and tetanus toxoid vaccines can be measured using the in vivo toxin neutralization assay.
Chan Woong Choi +7 more
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Preparation of Tetanus toxoid for equine [PDF]
Journal of Veterinary Medical Research, 2010 Tetanus toxoid for equines has been prepared by cultivation of C. tetani into new synthetic medium for production of high potent tetanus toxin which gave high flocculation units [90 Lf (Limit of flocculation)], and high minimum lethal dose (MLD) (600,000)
H. A. EL-Helw +2 more
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The effect of haloperidol, aminooxyacetic acid and (-)-nuciferine on prolonging survival time of mice with tetanus [PDF]
Veterinarski Glasnik, 2018 Introduction. Tetanus, also known as lockjaw, is a very dangerous, infectious, acute, usually afebrile disease characterised by muscle spasms. The causative agent of the disease is the bacterium Clostridium tetani.
Mujezinović Indira +2 more
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The monoclonal antibody 26 raised against tetanus toxoid also recognizes tetanus toxin and β2-glycoprotein I - its binding properties in vitro and potential applications [PDF]
Journal of the Serbian Chemical Society, 2009 A murine monoclonal IgG1 antibody, marked as MAb26, specific for tetanus toxoid has been immunochemically characterized. By performing enzyme-linked immunosorbent assays (ELISAs) and western blot analyses, it was demonstrated that MAb26 reacted with ...
Inić-Kanada Aleksandra B. +4 more
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The use of Soy hydrolysate for tetanus toxin production [PDF]
Veterinary Medical Journal - Giza, 2011 The present work was planned to develop a modified system for the growth of C. tetani and production of tetanus toxin, the system includes growth media that contain no meat or dairy by-products using non-animal based products.
Mahmoud M +3 more
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A Novel High-Potency Tetanus Vaccine
mBio, 2020 Chemically inactivated tetanus toxoid (CITT) is clinically effective and widely used. However, CITT is a crude nonmalleable vaccine that contains hundreds of Clostridium tetani proteins, and the active component is present in variable and sometimes minor
Amanda Przedpelski +4 more
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Studies on Tetanus Toxin and Toxoid IV. Interaction of Formaldehyde with Tetanus Toxin [PDF]
Australian Journal of Biological Sciences, 1969 The binding of formaldehyde with tetanus toxin under mild detoxificatIOn conditions (0 ·1M phosphate buffer, pH 7· 0, O· 005-0· 06M HCHO, 20-37°C) has been studied quantitatively by using [14C]formaldehyde. When detoxification was followed with time (0· 005M HCHO, 37°C) the toxin showed a characteristic immediate drop in lethality (~80%), followed by a
D J, Dawson, C M, Mauritzen
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The interaction of tetanus toxin and antitoxin [PDF]
Journal of Hygiene, 1953 Tetanus antitoxic horse sera were fractionated with sodium sulphate and by electrophoretic separation. The activity of the native serum and of fractions was determinedin vivoin the mouse and guinea-pig andin vitroby the flocculation method. All the sera and fractions showed several zones of flocculation.
B, CINADER, B, WEITZ
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Novel Small Molecule Inhibitors That Prevent the Neuroparalysis of Tetanus Neurotoxin
Pharmaceuticals, 2021 Tetanus neurotoxin (TeNT) is a protein exotoxin produced by Clostridium tetani that causes the deadly spastic neuroparalysis of tetanus. It consists of a metalloprotease light chain and of a heavy chain linked via a disulphide bond.
Giulia Zanetti +5 more
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The effect of tetanus toxin in the goldfish [PDF]
The Journal of Physiology, 1971 1. The effects of tetanus toxin have been investigated both on central nervous and peripheral neuromuscular systems of goldfish.2. Tetanus toxin kills goldfish when administered in minute doses. The lethal effect is temperature dependent. Unlike mammals, in which tetanus toxin produces spastic paralysis and convulsions, the tetanus‐intoxicated goldfish
J, Diamond, J, Mellanby
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