Studies on Tetanus Toxin and Toxoid IV. Interaction of Formaldehyde with Tetanus Toxin [PDF]
Australian Journal of Biological Sciences, 1969 The binding of formaldehyde with tetanus toxin under mild detoxificatIOn conditions (0 ·1M phosphate buffer, pH 7· 0, O· 005-0· 06M HCHO, 20-37°C) has been studied quantitatively by using [14C]formaldehyde. When detoxification was followed with time (0· 005M HCHO, 37°C) the toxin showed a characteristic immediate drop in lethality (~80%), followed by a
D J, Dawson, C M, Mauritzen
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The light chain but not the heavy chain of botulinum A toxin inhibits exocytosis from permeabilized adrenal chromaffin cells [PDF]
, 1989 The heavy and light chains of botulinum A toxin were separated by anion exchange chromatography. Their intracellular actions were studied using bovine adrenal chromaffin cells permeabilized with streptolysin O.
M. Gratzl +10 more
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The effect of tetanus toxin in the goldfish [PDF]
The Journal of Physiology, 1971 1. The effects of tetanus toxin have been investigated both on central nervous and peripheral neuromuscular systems of goldfish.2. Tetanus toxin kills goldfish when administered in minute doses. The lethal effect is temperature dependent. Unlike mammals, in which tetanus toxin produces spastic paralysis and convulsions, the tetanus‐intoxicated goldfish
J, Diamond, J, Mellanby
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Novel Small Molecule Inhibitors That Prevent the Neuroparalysis of Tetanus Neurotoxin
Pharmaceuticals, 2021 Tetanus neurotoxin (TeNT) is a protein exotoxin produced by Clostridium tetani that causes the deadly spastic neuroparalysis of tetanus. It consists of a metalloprotease light chain and of a heavy chain linked via a disulphide bond.
Giulia Zanetti +5 more
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An Unusual Case of Chronic Relapsing Tetanus Associated with Mandibular Osteomyelitis [PDF]
, 2009 A 55-year-old man underwent radiation therapy due to malignant lymphoma of the neck. Eight years after the therapy he developed tetanus. It appears that the radiation therapy resulted in mandibular necrosis, and that this lesion may have been the ...
Tomiyama, Masahiko +14 more
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Infection in a Geriatric Patient: Do Not Let Your Guard Off! [PDF]
Annals of Geriatric Medicine and Research, 2023 Tetanus is an infectious disease caused by Clostridium tetani toxin. Although easily preventable through vaccination, over 73,000 new infections and 35,000 deaths due to tetanus occurred worldwide in 2019, with higher rates in countries with healthcare ...
Alessandra Piscitelli +9 more
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Altered expression of the voltage-gated calcium channel subunit α2δ-1: a comparison between two experimental models of epilepsy and a sensory nerve ligation model of neuropathic pain. [PDF]
, 2014 The auxiliary α2δ-1 subunit of voltage-gated calcium channels is up-regulated in dorsal root ganglion neurons following peripheral somatosensory nerve damage, in several animal models of neuropathic pain.
Sandhu, G +11 more
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Maternal tetanus toxoid vaccination and neonatal mortality in rural North India [PDF]
, 2015 Objectives: Preventable neonatal mortality due to tetanus infection remains common. We aimed to examine antenatal vaccination impact in a context of continuing high neonatal mortality in rural northern India.
Singh, Abhishek +7 more
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International Journal of Emergency Medicine, 2021 Background Tetanus is a rare disease caused by Clostridium tetani, which produces tetanolysin and tetanospasmin. In 2018, there were only approximately ten tetanus cases reported in Indonesia.
Dzulfikar D. L. Hakim +6 more
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Molecular Aspects of Secretory Granule Exocytosis by Neurons and Endocrine Cells [PDF]
, 1994 Neuronal communication and endocrine signaling are fundamental for integrating the function of tissues and cells in the body. Hormones released by endocrine cells are transported to the target cells through the circulation.
MANFRED GRATZL, Gratzl, Manfred
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