Results 81 to 90 of about 328,500 (323)

Fluid flow enhances the effectiveness of toxin export by aquatic microorganisms: a first-passage perspective on microvilli and the concentration boundary layer [PDF]

open access: yes, 2014
A central challenge for organisms during development is determining a means to efficiently export toxic molecules from inside the developing embryo. For aquatic microorganisms, the strategies employed should be robust with respect to the variable ocean environment and limit the chances that exported toxins are reabsorbed.
arxiv   +1 more source

THE EFFECT OF CAROVERINE AND ITS COMBINATION WITH AMINOOXYACETIC ACID ON SURVIVAL TIME OF MICE WITH EXPERIMENTAL TETANUS

open access: yesVeterinaria, 2013
Tetanus is a disease that occurs in humans and various animal species worldwide. Tetanus toxin, after binding itself to nerve structures in the spinal cord, blocking the release of inhibitory transmitors which results in predominance of excitatory ...
Indira Mujezinović   +2 more
doaj  

Effects of Tetanus Toxin on Catecholamine Release from Intact and Digitonin-Permeabilized Chromaffin Cells [PDF]

open access: yes, 1988
Tetanus exotoxin inhibited Ca 2+ -dependent cate-cholamine secretion in a dose-dependent manner in digito-nin-permeabilized chromaffin cells. The inhibition was specific for tetanus exotoxin and the B fragment of tetanus toxin; the C fragment had no ...
Bittner, Mary A., Holz, Ronald W.
core   +1 more source

Integrated Efficacy and Safety Analysis of Abrocitinib in Adolescents With Moderate‐to‐Severe Atopic Dermatitis

open access: yesAllergy, EarlyView.
Data were included from adolescents with moderate‐to‐severe AD treated with the JAK1 inhibitor abrocitinib (200 mg/100 mg) across JADE clinical trials. Improvements in skin clearance (per EASI‐75) and itch (per PP‐NRS4) were maintained for up to 112 weeks with both abrocitinib doses.
Amy S. Paller   +13 more
wiley   +1 more source

Effect of immunization during pregnancy and pre-existing immunity on diphtheria-tetanus-acellular pertussis vaccine responses in infants

open access: yesEmerging Microbes and Infections, 2023
Immunization during pregnancy (IP) against pertussis is recommended in many countries to protect infants. Although maternal antibodies can influence the infants’ antibody responses to primary vaccinations, their effect on the development of functional ...
Aapo Knuutila   +8 more
doaj   +1 more source

The Action of Tetanus Toxin in Frogs [PDF]

open access: yesJournal of General Microbiology, 1961
SUMMARY: The development of tetanus intoxication in the frog is dependent on the environmental temperature being above about 15". The incubation period and time to death become shorter as the environmental temperature is raised. Cooling below about 15° prevents both the fixation of the toxin and its action after fixation but does not increase the speed
openaire   +3 more sources

Experimental Parkinsonism induced by tetanus toxin injected into basal ganglia

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Local inhibitory circuits and long‐range inhibitory projections within the interconnected basal ganglia nuclei are critical for control of voluntary movement and pathophysiology of different extrapyramidal movement disorders.
Patrik Meglić   +6 more
wiley   +1 more source

An Unusual Case of Tetanus Masquerading as an Acute Abdomen: A Case Report

open access: yesClinical Practice and Cases in Emergency Medicine, 2020
Introduction: Tetanus is an acute onset neurological disease that is often lethal. It has a high disease burden in low and middle-income countries. Tetanus is caused by a toxin made by spores of the bacterium Clostridium tetani, which are found in soil ...
Rahul Kumar Thakur   +3 more
doaj   +1 more source

Chronic silencing of subsets of cortical layer 5 pyramidal neurons has a long‐term influence on the laminar distribution of parvalbumin interneurons and the perineuronal nets

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 479-504, April 2025.
Chronic silencing of subsets of layer 5 projection neurons has distinct effects on the laminar distribution of PV interneurons and the perineuronal nets in the adult primary motor and somatosensory cortex. Abstract Neural networks are established throughout cortical development, which require the right ratios of glutamatergic and GABAergic neurons ...
Florina P. Szabó   +4 more
wiley   +1 more source

Single-species population models with age structure and psychological effect in a polluted environment [PDF]

open access: yesarXiv, 2022
This paper considers a single-population model with age structure and psychological effects in a polluted environment. We divide the single population into two stages of larval and adult structure. The model uses Logistic input, and the larvae are converted into adult bodies by constant ratio. We only consider adulthood.
arxiv  

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