Results 21 to 30 of about 16,622 (148)
Physics of muscle contraction [PDF]
Rep. Prog. Phys. 81, 036602 (2018), 2018 In this paper we report, clarify and broaden various recent efforts to complement the chemistry-centered models of force generation in muscles by mechanics-centered models. The physical mechanisms of interest can be grouped into two classes: passive and active.
arxiv +1 more source
International Journal of Infectious Diseases, 2020 Objective: To determine the seroprevalence of antibodies against of diphtheria, tetanus, and pertussis among Thai adolescents. Methods: A cross-sectional study was conducted among Thai adolescents aged 11–20 years who had completed five doses of ...
Pimpika Hanvatananukul +7 more
doaj
Toxins, 2016 Tetanus is caused by the tetanus neurotoxin (TeNT) and is one of the most dreaded diseases especially in the developing countries. The current vaccine against tetanus is based on an inactivated tetanus toxin, which is effective but has many drawbacks. In
Rui Yu +9 more
doaj +1 more source
A solid approach to biopharmaceutical stabilisation [PDF]
, 2018 Ensilication is a technology we developed that can physically stabilise proteins in silica without use of a pre-formed particle matrix. Stabilisation is done by tailor fitting individual proteins with a silica coat using a modified sol-gel process. Biopharmaceuticals, for example, liquid-formulated vaccines with adjuvants, have poor thermal stability ...
arxiv +1 more source
Tetanus Toxoid in Prophylaxis against Tetanus
Experimental Biology and Medicine, 1933 Ramon1 proposed the use of tetanus toxoid (anatoxin) for immunization against tetanus. He prepared the toxoid by adding from 3 to 4 cc. of formaldehyde to a liter of tetanus toxin, and then placing the mixture in an incubator at 37 C. for four weeks. In this manner he detoxified toxin that would kill a 300 Gm. guinea-pig in a dose of 0.0001 cc, so that
Samuel Etris, David H. Bergey
openaire +3 more sources
The monoclonal antibody 26 raised against tetanus toxoid also recognizes tetanus toxin and b2-glycoprotein I – its binding properties in vitro and potential applications [PDF]
Journal of the Serbian Chemical Society, 2009 A murine monoclonal IgG1 antibody, marked as MAb26, specific for tetanus toxoid has been immunochemically characterized. By performing enzyme-linked immunosorbent assays (ELISAs) and western blot analyses, it was demonstrated that MAb26 reacted with ...
ALEKSANDRA B. INIĆ-KANADA +4 more
doaj
Expert Review of Vaccines, 2019 Objectives: We evaluated memory responses and antibody persistence to diphtheria-toxoid, tetanus-toxoid, whole-cell-pertussis (DTwP), and Hepatitis-B vaccines in HIV-unexposed, HIV-exposed-uninfected and HIV-infected children previously randomized to ...
Omphile E. Simani +7 more
doaj +1 more source
Neonatal tetanus in St. Mary’s Hospital Lacor: A case report
Clinical Case Reports, 2020 Umbilical stump sepsis in a nonpassively immunized neonate poses a high risk to neonatal tetanus. Management of neonatal tetanus is still a great challenge in resource‐limited settings where some health facilities lack tetanus toxoid containing vaccines,
Ronald Okidi +2 more
doaj +1 more source
BMC Pregnancy and Childbirth, 2018 Background Globally, tetanus toxoid protective dose immunization of the mothers is one of the strategies of maternal and neonatal tetanus prevention. Ethiopia has planned the national tetanus protection at birth coverage to reach 86% by the year 2015 ...
Muhabaw Shumye Mihret +2 more
doaj +1 more source
Evaluation of the immune response to diphtheria and tetanus toxoids by the serological methods
Биопрепараты: Профилактика, диагностика, лечение, 2023 Scientific relevance. Currently, two types of methods are used to evaluate the potency of diphtheria and tetanus toxoids: the gold standard, which involves administering toxins to immunised animals, and serological methods, which involve quantifying ...
Е. I. Komarovskaya, A. A. Soldatov
doaj +1 more source