Results 151 to 160 of about 7,006 (230)

90K, an interferon-stimulated gene product, reduces the infectivity of HIV-1 [PDF]

, 2013
BACKGROUND: In response to viral infections, interferons induce the transcription of several hundred genes in mammalian cells. Specific antiviral functions, however, have only been attributed to a few of them.
Christian Dietz, Christian Kolbe, Christina M Stürzel, Christine Goffinet, Daniela Krnavek, Frank Kirchhoff, Jan Münch, Kristina Suhr, Nicola Schrott, Tanja Waldmann, Veronika Lodermeyer   +10 more
core   +1 more source

Serine Phosphorylation of HIV-1 Vpu and Its Binding to Tetherin Regulates Interaction with Clathrin Adaptors.

PLoS Pathogens, 2015
HIV-1 Vpu prevents incorporation of tetherin (BST2/ CD317) into budding virions and targets it for ESCRT-dependent endosomal degradation via a clathrin-dependent process. This requires a variant acidic dileucine-sorting motif (ExxxLV) in Vpu.
Tonya Kueck, Toshana L Foster, Julia Weinelt, Jonathan C Sumner, Suzanne Pickering, Stuart J D Neil   +5 more
doaj   +1 more source

Lack of adaptation to human tetherin in HIV-1 Group O and P

Retrovirology, 2011
Background HIV-1 viruses are categorized into four distinct groups: M, N, O and P. Despite the same genomic organization, only the group M viruses are responsible for the world-wide pandemic of AIDS, suggesting better adaptation to human hosts ...
Haworth Kevin G, Exline Colin M, Lopez Lisa A, Yang Su Jung, Cannon Paula M   +4 more
doaj   +1 more source

Release of Immunomodulatory Ebola Virus Glycoprotein-Containing Microvesicles Is Suppressed by Tetherin in a Species-Specific Manner.

Cell Reports, 2019
The Ebola virus glycoprotein (EBOV-GP) forms GP-containing microvesicles, so-called virosomes, which are secreted from GP-expressing cells. However, determinants of GP-virosome release and their functionality are poorly understood.
J. Nehls, R. Businger, M. Hoffmann, Constantin Brinkmann, B. Fehrenbacher, M. Schaller, B. Maurer, Caroline Schönfeld, D. Kramer, S. Hailfinger, S. Pöhlmann, M. Schindler   +11 more
semanticscholar   +1 more source

ISEV2025 Abstract Book

Journal of Extracellular Vesicles, Volume 14, Issue S1, October 2025.
wiley   +1 more source

Highlights from the HIV Cure and Reservoir Symposium, 11-12 September 2017, Ghent, Belgium [PDF]

, 2018
For the second time, the HIV Cure Research Center (HCRC) at Ghent University organised the HIV Cure and Reservoir Symposium, in Ghent, Belgium, where in this two-day conference, virologists, molecular biologists, immunologists and clinicians presented ...
Cole, Basiel, Kint, Sam, Sips, Magdalena, Van Hecke, Clarissa, Vandekerckhove, Linos   +4 more
core   +1 more source

Murine BST2/tetherin promotes measles virus infection of neurons.

Virology, 2021
Katelyn D. Miller, Christine M. Matullo, Riley M. Williams, Carli B. Jones, G. Rall   +4 more
semanticscholar   +1 more source

Tetherin is an exosomal tether

Tetherin is an exosomal tether
Exosomes are extracellular vesicles that are released when endosomes fuse with the plasma membrane. They have been implicated in various functions in both health and disease, including intercellular communication, antigen presentation, prion transmission, and tumour cell metastasis.
openaire  

AP2: an indispensable host factor in virus infection. [PDF]

J Virol
Li R, Jiang Y, Wang X, Zhang L, Wang Y.
europepmc   +1 more source

Catch Me if You Can: the Crosstalk of Zika Virus and the Restriction Factor Tetherin

, 2021
Marie-Luise Herrlein, Paul Schmanke, Fabian Elgner, Catarina Sabino, Sami Akhras, Daniela Bender, M. Glitscher, Denna Tabari, C. Scholl, J. Stingl, E. Hildt   +10 more
semanticscholar   +1 more source