Results 221 to 230 of about 90,627 (259)

Activation of DNMT1 by Chemically Synthesized Dual‐Monoubiquitinated PAF15 Protein

open access: yesAdvanced Science, EarlyView.
DNA methyltransferase 1 (DNMT1) propagates DNA methylation patterns during replication and is stimulated by dual‐monoubiquitinated PCNA‐associated factor 15 (PAF15Ub2). We chemically synthesized PAF15Ub2 with native isopeptide linkages. Cryo‐EM analysis of DNMT1 bound to the synthetic PAF15Ub2 and hemimethylated DNA revealed an active conformation with
Sae Suzuki   +7 more
wiley   +1 more source

Controlling Self‐Doping in Conjugated Polyelectrolyte Copolymers to Vary the Threshold Voltage in OECTs

open access: yesAdvanced Electronic Materials, EarlyView.
Two series of self‐doped conjugated polyelectrolytes are synthesized from a non‐self‐dopable building block 3MEEET and a self‐dopable building‐block 3HOT−[TMA+] or 3HOT−[SO3H] enabling precise control over the degree of self‐doping, which in turn directly governs the threshold voltage (VT) in OECTs over a wide range of 700 mV.
Julian Hungenberg   +7 more
wiley   +1 more source

The missing link: Piccolino is essential for tethering synaptic vesicles to rod photoreceptor ribbons. [PDF]

open access: yesJ Cell Biol
Gierke K   +15 more
europepmc   +1 more source

Multiscale Design of Anion Exchange Membrane‐Based Seawater Electrolysis for Sustainable Hydrogen Production

open access: yesAdvanced Energy Materials, EarlyView.
Direct seawater electrolysis using anion exchange membranes is emerging as a promising route for sustainable hydrogen production. This review summarizes multiscale design strategies from seawater chemistry and OER–ClER selectivity to catalysts, membranes, MEAs, cells, stacks, and system integration, providing a roadmap toward selective, durable, and ...
Chiho Kim   +7 more
wiley   +1 more source

Symptomatic and Urodynamic Outcomes After Spinal Cord De-Tethering in Primary Tethered Cord Patients. [PDF]

open access: yesNeurourol Urodyn
Reeson EA   +7 more
europepmc   +1 more source

Accelerating Biosensor Discovery: A Computationally‐Driven Pipeline for Microplastics Monitoring

open access: yesAdvanced Intelligent Discovery, EarlyView.
A computationally guided pipeline unites molecular simulation, synthetic biology, electrochemical engineering, and machine learning to accelerate biosensor discovery. A Bacillus anthracis carbohydrate‐binding module is used to develop a high‐performance micro‐ and nanoplastics sensor with greatly reduced error and variability.
Gabriel X. Pereira   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy