Results 51 to 60 of about 7,038 (204)

Charged tetracaine as an inactivation enhancer in batrachotoxin-modified Na+ channels

open access: yes, 1994
Two distinct types of local anesthetics (LAs) have previously been found to block batrachotoxin (BTX)-modified Na+ channels: type 1 LAs such as cocaine and bupivacaine interact preferentially with open channels, whereas type 2 LAs, such as benzocaine and
Wang, S.Y., Mok, W.M., Wang, G.K.
core   +1 more source

Sedative Effects of Dexmedetomidine and Ketamine or Dexmedetomidine and Midazolam on Tear Production, Ocular Perfusion Pressure and Pupil Diameter in Rabbits

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Sedative effects of intramuscular injection of dexmedetomidine and ketamine or dexmedetomidine and midazolam on tear production (TP), ocular perfusion pressure (OPP) and pupillary diameter (PD) in two groups of seven male New Zealand rabbits (G1 and G2, respectively).
Maryam Mohammadzadeh   +2 more
wiley   +1 more source

Prospective, randomized, contralateral eye comparison of tetracaine and proparacaine for pain control in laser in situ keratomileusis and photorefractive keratectomy

open access: yesClinical Ophthalmology, 2014
Majid Moshirfar,1 Mark D Mifflin,1 Michael V McCaughey,2 Adam J Gess1 1John A Moran Eye Center, University of Utah, Salt Lake City, UT, USA; 2University of New Mexico School of Medicine, Albuquerque, NM, USA Background: Tetracaine and proparacaine
Moshirfar M   +3 more
doaj  

Age and Sex Variation in the Duration of Action and Corneal Touch Threshold (CTT) following Instillation of 0.5% Topical Ophthalmic Proparacaine and Tetracaine Hydrochlorides

open access: yesJournal of Ophthalmology, 2021
Purpose. We investigated the effect of age and sex on corneal touch threshold (CTT) and duration of action following administration of 0.5% topical ophthalmic proparacaine and tetracaine hydrochlorides. Methods. A prospective, randomized, subject-masked,
Samuel Kyei   +4 more
doaj   +1 more source

Patch Test Results With the European Baseline Series, 2021/2022—Joint European Results of the ESSCAA and the EBSB Working Groups of the ESCD, and the GEIDACC

open access: yesContact Dermatitis, Volume 95, Issue 1, Page 17-32, July 2026.
ABSTRACT Background Patch test results obtained with the European Baseline Series (EBS) in its current version serve both contact allergy surveillance and (re‐)assessing the diagnostic value of EBS allergens. Objectives To present results of current EBS patch testing, obtained in 59 departments in 14 European countries during 2021 and 2022.
Wolfgang Uter   +73 more
wiley   +1 more source

Guidelines for Essential Trauma Care: Second Edition (2026)

open access: yesWorld Journal of Surgery, Volume 50, Issue 6, Page 1409-1450, June 2026.
Injury is a major cause of death and disability globally, with the highest burden in low‐ and middle‐income countries (LMICs). Strengthening the organization and planning for trauma care (care of the injured) can improve care and lower mortality. In 2004, the International Association for Trauma Surgery and Intensive Care (IATSIC) and the World Health ...
Charles Mock   +41 more
wiley   +1 more source

Improving mucosal anesthesia for awake endotracheal intubation with a novel method: a prospective, assessor-blinded, randomized controlled trial

open access: yesBMC Anesthesiology, 2020
Background Topical anesthesia is a crucial step in awake endotracheal intubation for providing favorable intubation conditions. The standard of care technique for awake intubation at our institution, which consists of oropharyngeal tetracaine spray, can ...
Chunji Han   +9 more
doaj   +1 more source

Complications associated with subpalpebral lavage systems in upper and lower equine eyelids: A prospective, randomised study in 73 cases (2015–2024)

open access: yesEquine Veterinary Journal, Volume 58, Issue 3, Page 692-698, May 2026.
Abstract Background Evidence for optimal location of subpalpebral lavage (SPL) systems is lacking. Objectives To compare the rate and types of complications with SPL systems located in central upper‐ compared with medial lower‐eyelid in hospitalised patients. Study Design Prospective, randomised treatment trial.
Annabelle E. Graham   +2 more
wiley   +1 more source

Comparison of Compound Lidocaine Cream and Lidocaine–Prilocaine Cream for Pain Management in Facial Rejuvenation: A Randomized Controlled Trial

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 4, April 2026.
ABSTRACT Background Effective pain management is essential for enhancing patient satisfaction and treatment compliance during facial rejuvenation procedures. Compound lidocaine cream and lidocaine–prilocaine cream are commonly used topical anesthetics in clinical practice; however, high‐quality randomized controlled trials directly comparing their ...
Li Liu   +6 more
wiley   +1 more source

Tetracaine downregulates matrix metalloproteinase activity and inhibits invasiveness of strongly metastatic MDA-MB-231 human breast cancer cells

open access: yes, 2023
Tetracaine, a long-acting amino ester-type local anesthetic, prevents the initiation and propagation of action potentials by reversibly blocking voltage-gated sodium channels (VGSCs). These channels, which are highly expressed in several carcinomas (e.g.
Didem Keleş   +9 more
core   +1 more source

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