Results 71 to 80 of about 7,038 (204)

Tetracaine – selective electrodes with polymer membranes and their application in pharmaceutical formulation control

open access: yes, 2017
The construction and electrochemical response characteristics of poly(vinyl chloride) (PVC) membrane electrodes for tetracaine hydrochloride (TCH) are described.
Hassan, Ahmed Khudhair   +2 more
core   +1 more source

Fluorescence study of tetracaine–cyclodextrin inclusion complexes [PDF]

open access: yes, 2010
The steady-state fluorescence emission from the local anaesthetic tetracaine (TCA) in water-solvent mixtures and in the presence of α-, β- and γ-cyclodextrin (CD) was investigated at various pH values.
Iglesias García, Iván.   +2 more
core   +1 more source

Tetracaine gel vs EMLA cream for percutaneous anaesthesia in children

open access: yes, 1999
We have evaluated the anaesthetic effect of tetracaine gel 1 g, applied for 45 min, compared with EMLA cream 2 g, applied for 60 min, in a randomized, double-blind study in 60 children aged 3-15 yr.
Rømsing, Janne   +3 more
core  

Topical tetracaine prior to arterial puncture: a randomized, placebo-controlled clinical trial

open access: yes, 2003
The objective of this randomized, double-blind, placebo-controlled clinical trial was to determine whether a topical anesthetic agent (tetracaine) provides effective local analgesia prior to radial arterial puncture. Tetracaine or placebo gel was applied
Sheila A Naftel   +9 more
core   +1 more source

Effects on pupil size and accommodation from topical lidocaine hydrochloride and tetracaine hydrochloride

open access: yes, 2007
PURPOSE: The aim of this study was to quantify the mydriatic and cycloplegic effects from topically applied lidocaine hydrochloride 4% and tetracaine hydrochloride 1% in healthy volunteers. METHODS: Twenty-six (26) healthy volunteers age 23 +/- 2.5 years
Behndig, Anders,
core   +1 more source

Drug binding sites on Nat1.8 sodium channels [PDF]

open access: yes, 2008
The voltage-gated sodium channel, Nav 1.8, is known to play an important role in pain signalling. In this thesis, the functional properties and drug binding sites of wild type and mutant Nav 1.8 sodium channel currents were studied in mammalian sensory ...
Browne, Liam Edward
core  

Tetracaine induces apoptosis through a mitochondrion-dependent pathway in human corneal stromal cells in vitro

open access: yes, 2018
Purpose: Tetracaine is a local anesthetic widely used in ocular diagnosis and ophthalmic surgery and may lead to some adverse effects and complications at a clinical dose.
Zhan Song (5445803)   +1 more
core   +1 more source

Formulation of Casein Hydrogels

open access: yesChemistry Proceedings
Protein-based hydrogels have attracted considerable interest due to their biocompatibility, nontoxic properties, biodegradability, and renewable nature, as well as their being inexpensive and easy to obtain. Hydrogel properties depend on the temperature,
Vanina A. Guntero   +4 more
doaj   +1 more source

Light-triggered release of conventional local anesthetics from a macromolecular prodrug for on-demand local anesthesia

open access: yesNature Communications, 2020
Local anesthetic sustained release systems suffer from untriggered rapid drug release upon application. Here the authors overcome this issue by covalently linking tetracaine to a polymer gel via a photo-cleavable linkage, enabling light-triggered and ...
Wei Zhang   +7 more
doaj   +1 more source

The Tetracaine Flare: Differences in Actions of Procaine and Tetracaine on Peripheral Nerve.

open access: yesExperimental Biology and Medicine, 1953
Summary1. Tetracaine hydrochloride, injected intradermally, produces a histaminelike flare which can be blocked hy procaine hydrochloride, 2. On the isolated nerve, tetracaine has much less effect on conduction in C fibers with respect to its effect on A fibers than is the case with procaine. (Preliminary experiments.) 3.
openaire   +2 more sources

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