Results 71 to 80 of about 10,453 (217)

Modeling the pore structure of voltage-gated sodium channels in closed, open, and fast-inactivated conformation reveals details of site 1 toxin and local anesthetic binding [PDF]

, 2018
In this work molecular modeling was applied to generate homology models of the pore region of the Na v 1.2 and Na v 1.8 isoforms of human voltage-gated sodium channels.
Blaney, Frank, Clare, Jeff, Dale, Tim, Guex, Nicolas, McLay, Iain, Robertson, Graeme, Scheib, Holger, Tate, Simon   +7 more
core  

Fluorescence study of tetracaine–cyclodextrin inclusion complexes [PDF]

, 2010
The steady-state fluorescence emission from the local anaesthetic tetracaine (TCA) in water-solvent mixtures and in the presence of α-, β- and γ-cyclodextrin (CD) was investigated at various pH values.
Brandariz, Isabel, Iglesias García, Iván., Iglesias, Emilia   +2 more
core   +2 more sources

Ultrasonographic Ocular Biometry of the Greater Caribbean Manatee (Trichechus manatus manatus)

Veterinary Ophthalmology, Volume 29, Issue 2, March 2026.
ABSTRACT This study aimed to characterize the ocular biometry of the Trichechus manatus manatus applying B‐mode ultrasonography across different age groups. Twenty‐two animals were assessed employing a portable ultrasound device equipped with a linear transducer. Five ocular parameters were assessed: corneal thickness (CT), anterior chamber depth (ACD),
Radan Elvis Matias de Oliveira, Fernanda Loffler Niemeyer Attademo, Rita de Kássia Matias de Oliveira, Romário Parente dos Santos, Fábia de Oliveira Luna, Antonio A. Mignucci‐Giannoni, Lesly J. Cabrias‐Contreras, Fabrício Bezerra de Sá, Flávio José de Lima Silva, Augusto Carlos da Bôaviagem Freire, Moacir Franco de Oliveira   +10 more
wiley   +1 more source

Comparing Effectiveness and Safety of Intravenous Atropine with Topical Tetracaine in Preventing and Relieving Oculocardiac Reflex in Patients Undergoing Strabismus Surgery: A Randomized Clinical Trial

Advanced Biomedical Research
Background: Oculocardiac reflex (OCR) is one of the serious complications following surgical therapeutic procedures for strabismus. Various medications have been tested to prevent or mitigate this complication.
Darioush Moradi Farsani, Seyed Ehsan Shakerinia   +1 more
doaj   +1 more source

Changes of SERCA activity have only modest effects on sarcoplasmic reticulum Ca2+ content in rat ventricular myocytes [PDF]

, 2011
: Changes of the activity of the sarco-endoplasmic reticulum Ca(2+)-ATPase (SERCA) affect the amplitude of the systolic Ca(2+) transient and thence cardiac contractility. This is thought to be due to alterations of SR Ca(2+) content.
Bode, EF, Briston, SJ, Eisner, DA, O'Neill, SC, Overend, CL, Trafford, AW   +5 more
core   +1 more source

Early sensorimotor restriction in rats induces age‐dependent mitochondrial alterations in skeletal muscles and brain structures

The Journal of Physiology, Volume 604, Issue 6, Page 2512-2524, 15 March 2026.
Abstract figure legend This study aimed to determine whether early sensorimotor restriction (SMR) alters mitochondrial enzyme activities in rat muscles and brain structures. SMR was induced via immobilizing the hind limbs of pups for 16 h per day during the dark phase from birth to postnatal day (PND) 28.
Mélanie Van Gaever, Olivier Dupuy, Erwan Dupont, Marie‐Hélène Canu, Frederic Daussin   +4 more
wiley   +1 more source

Comparing the Quality of Topical Anesthesia with Warmed or Cold Tetracaine in Cataract Surgery

مجله دانشکده پزشکی اصفهان, 2013
Background: Topical anesthesia in cataract surgery have several benefits compared with other methods of anesthesia; but there are not any studies aimed to assess the temperature of drug used for topical anesthesia. One of the most prevalent used drugs is
Mahmoud Saghaei, Leyla Jamali, Alireza Dehghan, Hasaanali Soltani, Kamran Montazeri   +4 more
doaj  

Effects of Gabaergic phenols on phospholipid bilayers as evaluated by 1H-NMR [PDF]

, 2013
The phenols propofol and thymol, and lately carvacrol, eugenol and chlorothymol, have been shown to act as positive allosteric modulators on GABAA receptor, which is the main inhibitory receptor of the central nervous system.
Fraceto, Leonardo Fernandes, Garcia, Daniel Asmed, Paula, Eneida de, Perillo, Maria Angelica, Reiner, Gabriela de Las Nieves   +4 more
core   +1 more source

Explosive Weapons Trauma Care Collective (EXTRACCT) Blast Injury Clinical Practice Guideline: Ocular Trauma

World Journal of Surgery, Volume 50, Issue 2, Page 289-297, February 2026.
This clinical practice guideline from the Explosive Weapons Trauma Care Collective (EXTRACCT) group reviews current best practice for the management of ocular trauma in conflict‐affected regions, where explosive weapons are used and healthcare infrastructure is limited.
Emma Butterfield, Alistair Bolt, Gerry Clare, John Mattia, Aung Maw Tin‐U, Iddi Ndyabawe, Larry Schwab, Siegfried Karl Wagner, On behalf of the EXTRACCT Clinical Practice Guidelines Collaboration   +8 more
wiley   +1 more source

Comparison of Intravitreal Bevacizumab versus Triamcinolone for the Treatment of Diffuse Diabetic Macular Edema [PDF]

, 2010
Background: Our purpose was to compare the effect of triamcinolone and bevacizumab (Avastin) on the retinal thickness and functional outcome in patients with diabetic macular edema. Methods and Materials: A collective of 32 patients, who had been treated
Al Saeidi, Rashid, Haritoglou, Christos, Kook, Daniel, Kreutzer, Thomas C., Neubauer, Aljoscha Steffen, Ulbig, Michael W., Wolf, Armin   +6 more
core   +1 more source