Results 61 to 70 of about 10,453 (217)
Journal of Biomedical Materials Research Part A, Volume 114, Issue 3, March 2026.ABSTRACT Age‐related macular degeneration (AMD) is a leading cause of irreversible vision loss in the aging population, with no curative treatment currently available. Current therapies primarily target late‐stage symptoms and are limited by their frequent and invasive intravitreal (IVT) injections.
Amna Abdalbaqi +4 more
wiley +1 more source
BMC Anesthesiology, 2020 Background Topical anesthesia is a crucial step in awake endotracheal intubation for providing favorable intubation conditions. The standard of care technique for awake intubation at our institution, which consists of oropharyngeal tetracaine spray, can ...
Chunji Han +9 more
doaj +1 more source
Local Anesthetics in Cancer: Mechanisms and Translational Perspectives
MedComm – Oncology, Volume 5, Issue 1, March 2026.Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang +4 more
wiley +1 more source
Optometry and Vision Science, Volume 103, Issue 3, March 2026.ABSTRACT Purpose To determine the effect of +2.50 D add multifocal soft contact lenses (MFSCLs) compared to +1.50 D add and single vision contact lenses (SVCLs) on the relationship between axial elongation and myopia progression. Methods Individual estimates of D/mm were derived from the CLEERE Study, then applied to data from 289 participants in the ...
Donald O. Mutti +8 more
wiley +1 more source
Preoperative electrophysiological characterization of patients with primary macula-involving rhegmatogenous retinal detachment [PDF]
, 2018 Purpose: To determine 1) which components of retinal function are impaired after rhegmatogenous retinal detachment, 2) which outer retinal pathways (rod- or cone-driven) are more severely affected, and 3) whether there is concomitant inner retinal ...
Apte, Rajendra +3 more
core +3 more sources
Modulation of Mitochondrial Bioenergetics in the Isolated Guinea Pig Beating Heart by Potassium and Lidocaine Cardioplegia: Implications for Cardioprotection [PDF]
, 2009 Mitochondria are damaged by cardiac ischemia/reperfusion (I/R) injury but can contribute to cardioprotection. We tested if hyperkalemic cardioplegia (CP) and lidocaine (LID) differently modulate mitochondrial (m) bioenergetics and protect hearts against ...
Aldakkak, Mohammed +5 more
core +2 more sources
Contact Dermatitis, Volume 94, Issue 3, Page 272-285, March 2026.Allergic contact dermatitis is very common in patients with anogenital lesions referred for patch testing in Spain. Key allergens include fragrances, preservatives and topical treatments like anaesthetics and steroids. Emerging sensitisers including benzisothiazolinone and sodium metabisulphite are also relevant.
Mercè Grau‐Pérez +29 more
wiley +1 more source
Atrial Myocyte Function and Ca2+ Handling Is Associated with Inborn Aerobic Capacity [PDF]
, 2015 Background: Although high aerobic capacity is associated with effective cardiac function, the effect of aerobic capacity on atrial function, especially in terms of cellular mechanisms, is not known. We aimed to investigate whether rats with low inborn
Alves, Marcia +10 more
core +3 more sources
Beyond the Ocular Surface: Nasal Sensory Input as a Driver of Reflex Lacrimation in Dogs
Veterinary Ophthalmology, Volume 29, Issue 2, March 2026.ABSTRACT Objective To evaluate the effect of nasal mucosal anesthesia on aqueous tear secretion in dogs and to compare responses between brachycephalic and non‐brachycephalic breeds. Animal Studied Twenty healthy dogs (10 Australian Shepherds, 10 Boston Terriers). Procedures All dogs received 0.5 mL of 10% lidocaine or saline into one randomly selected
Shelley W. Cochran +2 more
wiley +1 more source
Effect of Tetracaine on Intraocular Pressure in Normal and Hypertensive Rabbit Eyes
Journal of Ophthalmic & Vision Research, 2012 Purpose: To evaluate the effect of tetracaine on intraocular pressure (IOP) in normal and hypertensive rabbit eyes. Methods: The study was conducted on 12 healthy rabbits as controls and 6 healthy rabbits in which an experimental model of ocular ...
Ali Asghar Sarchahi, Hooman Bozorgi
doaj