Results 141 to 150 of about 3,260 (193)
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Aerosol-OT Microemulsions as Transdermal Carriers of Tetracaine Hydrochloride
Drug Development and Industrial Pharmacy, 2000The aerosol-OT (AOT)/water/isopropyl myristate microemulsion was investigated as a carrier in transdermal drug delivery of tetracaine hydrochloride. The study included in vivo analgesic studies on rats and histopathological, irritation, and oxidative stress measurements on mice. The tetracaine hydrochloride encapsulated in AOT/water/isopropyl myristate
M, Changez, M, Varshney
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Mechanism of Action of Tetracaine Hydrochloride against Pseudomonas aeruginosa
Journal of Infectious Diseases, 1977The mode of action of tetracaine hydrochloride in vitro on Pseudomonas aeruginosa was investigates. The inhibitory and bactericidal action of tetracaine hydrochloride in vitro was adversely affected by magnesium ions. Observation of cellular lysis, leakage of intracellular materials, dehydrogenase activity, and a higher sensitivity of spheroplasts than
Y W, Leung, B D, Rawal
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INTRAVENOUS ADMINISTRATION OF TETRACAINE (PONTOCAINE®) HYDROCHLORIDE
Archives of Internal Medicine, 1950DURING the last eight years numerous reports have been published on the intravenous use of procaine (novocain ® ) hydrochloride. In the United States interest has centered mainly on administration in the slow intravenous drip of 0.1 and 0.2 per cent solutions, taking from twenty minutes to an hour and a half.
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A GRAVE REACTION TO LOCALLY APPLIED TETRACAINE HYDROCHLORIDE
Archives of Otolaryngology - Head and Neck Surgery, 1945For the past seven years tetracaine hydrochloride has been used by the members of the department of bronchoesophagology of the University of Virginia Hospital to obtain anesthesia of the mucosa of the upper air and food passages preparatory to endoscopic examination. There had never been any untoward reactions to the drug in our experience, and we felt
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Biochimica et Biophysica Acta (BBA) - Biomembranes, 1969
High resolution NMR spectroscopy has been applied to the study of the interaction of two local anaesthetic molecules, procaine·HCl and tetracaine·HCl, with phospholipid dispersions. Interaction occurred with the acidic phospholipid phosphatidylserine but not with zwitterionic lecithin, indicating that the interaction was of an electrostatic nature. Van
H, Hauser, S A, Penkett, D, Chapman
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High resolution NMR spectroscopy has been applied to the study of the interaction of two local anaesthetic molecules, procaine·HCl and tetracaine·HCl, with phospholipid dispersions. Interaction occurred with the acidic phospholipid phosphatidylserine but not with zwitterionic lecithin, indicating that the interaction was of an electrostatic nature. Van
H, Hauser, S A, Penkett, D, Chapman
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Journal of Ocular Pharmacology and Therapeutics, 2007
The aim of this study was to quantify the mydriatic and cycloplegic effects from topically applied lidocaine hydrochloride 4% and tetracaine hydrochloride 1% in healthy volunteers.Twenty-six (26) healthy volunteers age 23 +/- 2.5 years were included in this double-masked, randomized, intraindividually comparing study. All participants were given a drop
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The aim of this study was to quantify the mydriatic and cycloplegic effects from topically applied lidocaine hydrochloride 4% and tetracaine hydrochloride 1% in healthy volunteers.Twenty-six (26) healthy volunteers age 23 +/- 2.5 years were included in this double-masked, randomized, intraindividually comparing study. All participants were given a drop
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Cornea, 2017
Purpose: To identify pharmacodynamic (PD) and pharmacokinetic (PK) metrics that aid in mechanistic understanding of dosage considerations for prolonged corneal anesthesia. Methods: A rabbit model using 0.5% tetracaine hydrochloride was used to induce corneal anesthesia in ...
Jason, Ethington +2 more
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Purpose: To identify pharmacodynamic (PD) and pharmacokinetic (PK) metrics that aid in mechanistic understanding of dosage considerations for prolonged corneal anesthesia. Methods: A rabbit model using 0.5% tetracaine hydrochloride was used to induce corneal anesthesia in ...
Jason, Ethington +2 more
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Systemic allergic dermatitis during tetracaine hydrochloride patch testing
Contact Dermatitis, 2021Katharina Hansel +6 more
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Viscous tetracaine hydrochloride 0.5% for topical anesthesia in cataract surgery
Expert Review of Ophthalmology, 2008For the past decade, lidocaine 2% gel has been one of the more commonly used agents for topical anesthesia in cataract surgery, particularly in the USA. Given its prolonged contact time with the ocular surface by nature of its viscosity, it has been found to provide superior anesthesia relative to anesthetic drops.
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