Effects of Sapropterin on Endothelium-Dependent Vasodilation in Patients With CADASIL: A Randomized Controlled Trial [PDF]
Background and Purpose-Cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a rare autosomal dominant disorder caused by NOTCH3 mutations, is characterized by vascular smooth muscle and endothelial cells ...
Campolo, Jonica+6 more
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Tetrahydrobiopterin Improves Endothelium-Dependent Vasodilation in Chronic Smokers [PDF]
Thomas Heitzer+7 more
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Ascorbic Acid Enhances Endothelial Nitric-oxide Synthase Activity by Increasing Intracellular Tetrahydrobiopterin [PDF]
Annong Huang+3 more
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Allosteric regulation of neuronal nitric oxide synthase by tetrahydrobiopterin and suppression of auto-damaging superoxide [PDF]
Peter Kotsonis+5 more
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Clinical, Biochemical, and Radiologic Profiles of Filipino Patients with 6-Pyruvoyl-Tetrahydrobiopterin Synthase (6-PTPS) Deficiency and their Neurodevelopmental Outcomes. [PDF]
de Castro-Hamoy LG+8 more
europepmc +1 more source
Effects of 6R-tetrahydrobiopterin on calcium channels in neuronal cells.
Kunio Koshimura+5 more
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Oral Administration of Tetrahydrobiopterin Prevents Endothelial Dysfunction and Vascular Oxidative Stress in the Aortas of Insulin-Resistant Rats [PDF]
Kazuya Shinozaki+9 more
openalex +1 more source
Rare biochemical & genetic conditions: clues for broader mechanistic insights. [PDF]
Mentis AA, Dalamaga M.
europepmc +1 more source