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Safety of Cannabis sativaL. extract as a novel food pursuant to Regulation (EU) 2015/2283 [PDF]

open access: yesEFSA J
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on Cannabis sativa L. extract as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF consists of 57%–65% w/w cannabidiol (CBD) and 9%–17% w/w of other cannabinoids.
EFSA Panel on Nutrition   +26 more
europepmc   +2 more sources
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Delta-8 tetrahydrocannabinol, delta-10 tetrahydrocannabinol, and tetrahydrocannabinol-O acetate exposures reported to America’s Poison Centers

Clinical Toxicology
Since the passage of the Farm Bill in 2018, the availability of synthetic tetrahydrocannabinols has increased, including delta-8 tetrahydrocannabinol, delta-10 tetrahydrocannabinol, and tetrahydrocannabinol-O acetate. The objective of this study is to investigate the characteristics of delta-8 tetrahydrocannabinol, delta-10 tetrahydrocannabinol, and ...
Henry Spiller, Natalie Rine
exaly   +3 more sources

Tetrahydrocannabinol [PDF]

open access: yesReactions Weekly, 2023
(-)-Δ-trans-tetrahydrocannabinol (THC), which is the principal psychoactive constituent of Cannabis, mediates its action by binding to two members of the G-protein-coupled receptor (GPCR) family: the cannabinoid CB (CBR) and CB (CBR) receptors. Molecular
Nil Casajuana-Martin   +21 more
openaire   +2 more sources

Tetrahydrocannabinol and acetylcholinesterase

Pharmacology Biochemistry and Behavior, 1978
Recent evidence suggests that the psychoactive effect of delta-9-tetrahydrocannabinol (delta9-THC), the major psychoactive constituent of marihuana, may be mediated through an alteration of cholinergic neurotransmission. One possible mechanism by which delta9-THC could have its effect is by affecting acetylcholinesterase (AChE) and there is evidence ...
D E, Moss, P L, Peck, R, Salome
openaire   +2 more sources

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