Results 261 to 270 of about 48,054 (298)

Tetrahydrocannabinol and acetylcholinesterase

Pharmacology Biochemistry and Behavior, 1978
Recent evidence suggests that the psychoactive effect of delta-9-tetrahydrocannabinol (delta9-THC), the major psychoactive constituent of marihuana, may be mediated through an alteration of cholinergic neurotransmission. One possible mechanism by which delta9-THC could have its effect is by affecting acetylcholinesterase (AChE) and there is evidence ...
D E, Moss, P L, Peck, R, Salome
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Synthetic Tetrahydrocannabinol

Journal of Forensic Sciences, 1983
Abstract This paper presents the synthetic route used and the identification of the precursors and reaction products in a clandestine laboratory manufacture of cannabidiol (CBD), μ9-cis-tetrahydrocannabinol (μ9)-cis-THC), and μ9-trans-tetrahydrocannabinol (μ9-trans-THC).
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Stability of Tetrahydrocannabinols II

Journal of Pharmaceutical Sciences, 1978
The biphasic degradation of delta9-tetrahydrocannabinol (I), as monitored by flame-ionization GLC, produced delta8-tetrahydrocannabinol (II), cannabidiol (X), 9-hydroxyhexahydrocannabinol (VI), 9,10-dihydro-9-hydroxyisocannabidiol (VI), and and 6,12-dihydro-6-hydroxycannabidiol (VIII) in acidic solutions.
E R, Garrett, A J, Gouyette, H, Roseboom
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Psychological Effects of Tetrahydrocannabinol

Archives of General Psychiatry, 1970
THE MORE widespread use of marihuana and marihuana-like drugs in the general population and the controversy about their possible harmful, as well as beneficial, effects have led to an increased interest in studying these compounds during the last few years.
I E, Waskow, J E, Olsson, C, Salzman, M M, Katz   +3 more
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Phytocannabinoids: Tetrahydrocannabinol (THC)

2021
Cannabis includes several species, the popular ones being Cannabis sativa, Cannabis indica, and Cannabis ruderalis. Cannabinoids are chemicals either derived from cannabis (phytocannabinoids) like cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC); synthetic medications like nabilone, dronabinol, and rimonabant; or endogenous chemicals that stimulate ...
Priodarshi Roychoudhury, Ning Nan Wang, Samer N. Narouze   +2 more
openaire   +1 more source

Stability of Tetrahydrocannabinols I

Journal of Pharmaceutical Sciences, 1974
Δ9-Tetrahydrocannabinol, as monitored by flame-ionization GLC at various temperatures, degrades by a biphasic semilogarithmic curve with time in acidic aqueous solutions (
E R, Garrett, J, Tsau
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Intravenous Δ9-Tetrahydrocannabinol

Anesthesiology, 1975
Delta9-Tetrahydrocannabinol (THC), the active component of marijuana, was studies to determine whether it might be useful for preanesthetic medication. Ten healthy subjects received THC intravenously in logarithmically spaced incremental doses. Four subjects received a total cumulatine dose of 135 mug/kg and four others, 201 mug/kg, Two of the ten ...
Lee A. Malit, Robert E. Johnstone, Denis I. Bourke, Robyn A. Kulp, Virginia Klein, Theodore C. Smith   +5 more
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Hypothermic action of Δ9-tetrahydrocannabinol, 11-hydroxy-Δ9-tetrahydrocannabinol and 11-hydroxy-Δ8-tetrahydrocannabinol in mice

Life Sciences, 1973
The hypothermic activity of Δ9-tetrahydrocannabinol (Δ9-THC), a metabolite, 11-hydroxy-Δ9-tetrahydrocannabinol (11-OH-Δ9-THC) and 11-hydroxy-Δ8-tetrahydrocannabinol (11-OH-Δ8-THC) has been determined in male mice maintained at an ambient temperature of 20 ± 1°C. The mean body temperature of mice that received 2, 4, 16 or 32 mg/kg, i.
C O, Haavik, H F, Hardman
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Delta-8 tetrahydrocannabinol, delta-10 tetrahydrocannabinol, and tetrahydrocannabinol-O acetate exposures reported to America’s Poison Centers

Clinical Toxicology
Since the passage of the Farm Bill in 2018, the availability of synthetic tetrahydrocannabinols has increased, including delta-8 tetrahydrocannabinol, delta-10 tetrahydrocannabinol, and tetrahydrocannabinol-O acetate. The objective of this study is to investigate the characteristics of delta-8 tetrahydrocannabinol, delta-10 tetrahydrocannabinol, and ...
Alice Burgess, Hannah L. Hays, Jaahnavi Badeti, Henry A. Spiller, Natalie I. Rine, Christopher E. Gaw, Kele Ding, Gary A. Smith   +7 more
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Biotransformation of Tetrahydrocannabinol

Phytochemistry Reviews, 2015
Cannabinoids are terpenophenolic compounds consisting of an aromatic polyketide and derived from the geranyl diphosphate C10 terpenoid unit. They are the active constituents in Cannabis sativa and have been utilized in a number of cannabis-based medicines.
Muhammad T. Akhtar, Khozirah Shaari, Robert Verpoorte   +2 more
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