Results 31 to 40 of about 13,831 (202)
Scientific Reports, 2023 Tumor cells generally require large amounts of nucleotides, and thus activate de novo purine synthesis (dnPS). In the dnPS reactions, 10-formyltetrahydorofolate (10-fTHF) supplied by one-carbon metabolism is utilized as a formyl group donor.
Masato Sasaki +9 more
doaj +1 more source
Genomic potential and physiological characteristics of C1 metabolism in novel acetogenic bacteria
Frontiers in Microbiology, 2023 Acetogenic bacteria can utilize C1 compounds, such as carbon monoxide (CO), formate, and methanol, via the Wood-Ljungdahl pathway (WLP) to produce biofuels and biochemicals.
Jihyun Yu +17 more
doaj +1 more source
Biomédica: revista del Instituto Nacional de Salud, 2013 Introducción. La dihidrofolato reductasa (DHFR) se ha utilizado como blanco molecular en tratamientos antibacterianos, anticancerígenos y antipalúdicos.
Edison Osorio +4 more
doaj +1 more source
The toxic side of one-carbon metabolism and epigenetics
Redox Biology, 2021 One-carbon metabolism is a central metabolic hub that provides one-carbon units for essential biosynthetic reactions and for writing epigenetics marks.
Agustín E. Morellato +2 more
doaj +1 more source
Draft Genome Sequences of Facultative Methylotrophs, Gemmobacter sp. Strain LW1 and Mesorhizobium sp. Strain 1M-11, Isolated from Movile Cave, Romania [PDF]
, 2015 Facultative methylotrophs belonging to the genera Gemmobacter and Mesorhizobium were isolated from microbial mat and cave water samples obtained from the Movile Cave ecosystem. Both bacteria can utilize methylated amines as their sole carbon and nitrogen
Hillebrand-voiculescu, Alexandra M. +3 more
core +1 more source
Frontiers in Nutrition, 2023 Folate-mediated one-carbon metabolism (FOCM) is closely associated with postharvest preservation. This study investigated the effects of exogenous nitric oxide (NO) on FOCM, storage quality, energy metabolism, and mitochondrial membrane integrity in cold-
Zhifeng Yang +6 more
doaj +1 more source
LC-MS proteomics analysis of the iInsulin/IGF-1-deficient Caenorhabditis elegans daf-2(e1370) mutant reveals extensive restructuring of intermediary metabolism [PDF]
, 2014 The insulin/IGF-1 receptor is a major known determinant of dauer formation, stress resistance, longevity, and metabolism in Caenorhabditis elegans. In the past, whole-genome transcript profiling was used extensively to study differential gene expression ...
Braeckman, Bart +7 more
core +2 more sources
Complete genome sequence of Syntrophobacter fumaroxidans strain (MPOB(T)). [PDF]
, 2012 Syntrophobacter fumaroxidans strain MPOB(T) is the best-studied species of the genus Syntrophobacter. The species is of interest because of its anaerobic syntrophic lifestyle, its involvement in the conversion of propionate to acetate, H2 and CO2 during ...
Crable, Bryan R +15 more
core +2 more sources
A systems biology approach uncovers cellular strategies used by Methylobacterium extorquens AM1 during the switch from multi- to single-carbon growth. [PDF]
PLoS ONE, 2010 When organisms experience environmental change, how does their metabolic network reset and adapt to the new condition? Methylobacterium extorquens is a bacterium capable of growth on both multi- and single-carbon compounds.
Elizabeth Skovran +4 more
doaj +1 more source
Engineering Proceedings, 2023 The genome sequence of Leishmania has given rise to diverse novel drug targets, and their identification remains the first step in drug discovery. This study aims to identify the possible anti-leishmanicidal activity target(s) of N1, N4-[dibenzylbutane-4′
Ikenna F. Ezema +5 more
doaj +1 more source