Results 11 to 20 of about 13,790 (193)

Genomic and Transcriptomic Insights Into the Autotrophic Metabolism on H₂ + CO₂ or CO of the Thermophilic Acetogenic Model Organism Moorella thermoacetica. [PDF]

Environ Microbiol
Moorella thermoacetica is the model organism for elucidation of acetogenesis. The reduction of CO2 to acetate is well studied, but how redox carrier balancing and energy conservation are maintained during autotrophic growth and how H2 is oxidised remains enigmatic.
Rosenbaum FP, Poehlein A, Daniel R, Müller V.   +3 more
europepmc   +2 more sources

Crystal Structure and Sequence Analysis of N⁵, N¹⁰-Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase Enzyme from Porphyromonas gingivalis

Crystals, 2023
The methylenetetrahydrofolate dehydrogenase–cyclohydrolase (FolD) enzyme has a dual activity of N5,N10-methylenetetrahydrofolate dehydrogenase and cyclohydrolase.
Sehyeok Im, Hackwon Do, Jisub Hwang, Youn-Soo Shim, Jun Hyuck Lee   +4 more
doaj   +1 more source

Prevalence and determinants of folic acid uptake among women of childbearing age in the Ho municipality of the volta region of Ghana

International Journal of Food Properties, 2022
Folic acid is an essential vitamin that is found in certain green lush vegetables, such as kale, spinach, and cabbage. An estimated 300,000 children are born with NTDs globally each year resulting in the death of approximately 88,000.
Lucy Makafui Nutakor, Stephen Manortey
doaj   +1 more source

Serine biosynthesis with one carbon catabolism represents a novel pathway for ATP generation in cells using alternative glycolysis with zero net ATP production [PDF]

, 2011
Recent experimental evidence indicates that some cancer cells have an alternative glycolysis pathway with net zero ATP production, implying that upregulation of glycolysis in these cells may not be related to the generation of ATP.
Alexei Vazquez, Elke K. Markert, Zoltan N. Oltvai   +2 more
core   +5 more sources

Genetic polymorphism rs6922269 in the MTHFD1L gene is associated with survival and baseline active vitamin B12 levels in post-acute coronary syndromes patients. [PDF]

PLoS ONE, 2014
BACKGROUND AND AIMS: The methylene-tetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (MTHFD1L) gene is involved in mitochondrial tetrahydrofolate metabolism.
Barry R Palmer, Sandy Slow, Katrina L Ellis, Anna P Pilbrow, Lorraine Skelton, Chris M Frampton, Suetonia C Palmer, Richard W Troughton, Tim G Yandle, Rob N Doughty, Gillian A Whalley, Michael Lever, Peter M George, Stephen T Chambers, Chris Ellis, A Mark Richards, Vicky A Cameron   +16 more
doaj   +1 more source

A Common Polymorphism in the MTHFD1 Gene Is a Modulator of Risk of Congenital Heart Disease

Journal of Cardiovascular Development and Disease, 2022
Several environmental and genetic factors may influence the risk of congenital heart defects (CHDs), which can have a substantial impact on pediatric morbidity and mortality. We investigated the association of polymorphisms in the genes of the folate and
Nataša Karas Kuželički, Alenka Šmid, Maša Vidmar Golja, Tina Kek, Borut Geršak, Uroš Mazič, Irena Mlinarič-Raščan, Ksenija Geršak   +7 more
doaj   +1 more source

Anaerobic Carbon Monoxide Dehydrogenase Diversity in the Homoacetogenic Hindgut Microbial Communities of Lower Termites and the Wood Roach [PDF]

, 2011
Anaerobic carbon monoxide dehydrogenase (CODH) is a key enzyme in the Wood-Ljungdahl (acetyl-CoA) pathway for acetogenesis performed by homoacetogenic bacteria.
A Brauman, A Ebert, A Marchler-Bauer, B Soboh, BJ Paster, CL Drennan, CL Drennan, CM Perez, DA Odelson, DM Bodenmiller, E Matson, E Oelgeschläger, E Pezacka, E Pierce, EG Matson, EJ Gagen, Eric G. Matson, F Warnecke, FH Martin, GM King, H Dobbek, HJ Beaumont, HL Drake, HL Drake, HL Drake, HL Drake, J Heo, J Heo, JA Breznak, JA Breznak, Jared R. Leadbetter, JG Ferry, JM González, JR Graber, JR Graber, JR Leadbetter, K Fujinaga, Kasia G. Gora, KH Yeoman, M Köpke, M Pester, M Wu, MA Larkin, MD Kane, R Overbeek, RE Hungate, RL Kerby, S Huang, S Kambhampati, SF Altschul, SW Ragsdale, SW Ragsdale, SW Ragsdale, SW Singer, T Beckwith, TG Lilburn, TI Doukov, TM Salmassi, V Svetlitchnyi, V Svetlitchnyi, Vasu D. Appanna, W Ludwig, X Zhang   +62 more
core   +7 more sources

Folate Related Pathway Gene Analysis Reveals a Novel Metabolic Variant Associated with Alzheimer’s Disease with a Change in Metabolic Profile

Metabolites, 2022
Metabolic disorders may be important potential causative pathways to Alzheimer’s disease (AD). Cerebrospinal fluid (CSF) decreasing output, raised intracranial pressure, and ventricular enlargement have all been linked to AD.
Jaleel Miyan, Charlotte Buttercase, Emma Beswick, Salma Miyan, Ghazaleh Moshkdanian, Naila Naz   +5 more
doaj   +1 more source

Metagenome Assembled Genome of a Novel Verrucomicrobial Methanotroph From Pantelleria Island

Frontiers in Microbiology, 2021
Verrucomicrobial methanotrophs are a group of aerobic bacteria isolated from volcanic environments. They are acidophiles, characterized by the presence of a particulate methane monooxygenase (pMMO) and a XoxF-type methanol dehydrogenase (MDH ...
Nunzia Picone, Pieter Blom, Carmen Hogendoorn, Jeroen Frank, Theo van Alen, Arjan Pol, Antonina L. Gagliano, Mike S. M. Jetten, Walter D’Alessandro, Paola Quatrini, Huub J. M. Op den Camp   +10 more
doaj   +1 more source

Sex-Specific Metabolic Effects of Dietary Folate Withdrawal in Wild-Type and Aldh1l1 Knockout Mice

Metabolites, 2022
ALDH1L1 (10-formyltetrahydrofolate dehydrogenase), an enzyme of folate metabolism, is highly expressed in the liver. It regulates the overall flux of folate-bound one-carbon groups by converting 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in a ...
Jaspreet Sharma, Blake R. Rushing, Madeline S. Hall, Kristi L. Helke, Susan L. McRitchie, Natalia I. Krupenko, Susan J. Sumner, Sergey A. Krupenko   +7 more
doaj   +1 more source