Results 61 to 70 of about 13,656 (172)

A novel gamma-N-methylaminobutyrate demethylating oxidase involved in catabolism of the tobacco alkaloid nicotine by Arthrobacter nicotinovorans pAO1 [PDF]

, 2004
Nicotine catabolism, linked in Arthrobacter nicotinovorans to the presence of the megaplasmid pAO1, leads to the formation of gamma-N-methylaminobutyrate from the pyrrolidine ring of the alkaloid.
Brandsch, R, Chiribau, Calin B., Chiribau, CB, Fraaije, M, Sandu, C, Schiltz, E   +5 more
core   +2 more sources

NeuralFlux: Estimation of Reaction Fluxes at a Genome‐Scale Level From Time‐Resolved Isotope Labelling Patterns Using Deep Learning

Plant Biotechnology Journal, EarlyView.
Sebastian Huß, Zoran Nikoloski
wiley   +1 more source

Methylene tetrahydrofolate dehydrogenase/cyclohydrolase and the synthesis of 10‐CHO‐THF are essential inLeishmania major [PDF]

Molecular Microbiology, 2009
Summary10‐Formyl tetrahydrofolate (10‐CHO‐THF) is a key metabolite in C1 carbon metabolism, arising through the action of formate‐tetrahydrofolate ligase (FTL) and/or 5,10‐methenyltetrahydrofolate cyclohydrolase/5,10‐methylene tetrahydrofolate dehydrogenase (DHCH).Leishmania majorpossesses singleDHCH1andFTLgenes encoding exclusively cytosolic proteins,
Silvane M F, Murta, Tim J, Vickers, David A, Scott, Stephen M, Beverley   +3 more
openaire   +2 more sources

Comparative biochemistry of CO2 fixation and the evolution of autotrophy [PDF]

, 2010
Carbon dioxide fixation is a polyphyletic trait that has evolved in widely separated prokaryotic branches. The three principal CO2-assimilation pathways are (i) the reductive pentose-phosphate cycle, i. e.
Ana María Velasco, Antonio Lazcano, Arturo Becerra, Juli G. Peretó   +3 more
core   +2 more sources

The role of the folate pathway in pancreatic cancer risk.

PLoS ONE, 2018
BackgroundPancreatic cancer is the third leading cause of cancer related deaths in the United States. Several dietary factors have been identified that modify pancreatic cancer risk, including low folate levels.
Shirisha Chittiboyina, Zhongxue Chen, E Gabriela Chiorean, Lisa M Kamendulis, Barbara A Hocevar   +4 more
doaj   +1 more source

One-carbon metabolism in cancer [PDF]

, 2017
Cells require one-carbon units for nucleotide synthesis, methylation and reductive metabolism, and these pathways support the high proliferative rate of cancer cells.
AJ MacFarlane, Alice C Newman, AS Tibbetts, B Chaneton, BC Blount, C Commisso, CA Lewis, CF Labuschagne, CF Woeller, D Hanahan, D Hanahan, D Kim, DD Anderson, E Currie, E Mullarky, F Daidone, F Kottakis, G Kikuchi, GM DeNicola, Gregory S. Ducker, GS Ducker, J Liu, J Meiser, J Ye, Jason W. Locasale, JJ Kamphorst, JW Locasale, K Snell, K Snell, K Snell, Katherine R. Mattaini, L Galluzzi, M Goulian, M Jain, M Kulis, Mahya Mehrmohamadi, ME Pacold, Ming Yang, MJ Osborn, ML Rose, ML Rose, OD Maddocks, OD Maddocks, Oliver D K Maddocks, Oliver D. K. Maddocks, PM Ueland, R Possemato, S Farber, S Kit, S Pollari, SJ Mentch, Swetha Bolusani, T Shlomi, WC Zhang, Y Fu, Z Ser   +55 more
core   +1 more source

Carbon assimilation strategies in ultrabasic groundwater: clues from the integrated study of a serpentinization-influenced aquifer [PDF]

, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Seyler, L. M., Brazelton, W. J., McLean, C., Putman, L. I., Hyer, A., Kubo, M. D.
Brazelton, William J., Cardace, Dawn, Hoehler, Tori M., Hyer, Alex, Kubo, Michael D. Y., McLean, Craig, Putman, Lindsay I., Schrenk, Matthew O., Seyler, Lauren M.   +8 more
core   +2 more sources

Cancer metabolism at a glance [PDF]

, 2016
A defining hallmark of cancer is uncontrolled cell proliferation. This is initiated once cells have accumulated alterations in signaling pathways that control metabolism and proliferation, wherein the metabolic alterations provide the energetic and ...
Gottlieb, Eyal, Kamphorst, Jurre J., Markert, Elke K., Schug, Zachary T., Tardito, Saverio, Vazquez, Alexei   +5 more
core   +2 more sources

Genome-Resolved Proteomic Stable Isotope Probing of Soil Microbial Communities Using 13CO2 and 13C-Methanol. [PDF]

, 2019
Stable isotope probing (SIP) enables tracking the nutrient flows from isotopically labeled substrates to specific microorganisms in microbial communities. In proteomic SIP, labeled proteins synthesized by the microbial consumers of labeled substrates are
Banfield, Jillian F, Crits-Christoph, Alexander, Guo, Xuan, Hervey, William Judson, Hettich, Robert L, Hurst, Gregory B, Lebeis, Sarah L, Li, Zhou, Mayes, Melanie A, Pan, Chongle, Yao, Qiuming   +10 more
core   +1 more source

Biochemical and haematological aspects of ethanol metabolism in humans : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University, New Zealand [PDF]

, 1983
Macrocytosis or raised mean cell volume (MCV) (which as measured by the Coulter S counter) is one of the results of alcohol abuse. There is a need to identify (chronic) alcoholics by laboratory tests.
Kwok, Hon Wing
core