Results 11 to 20 of about 5,026 (197)

Forty new genomes shed light on sexual reproduction and the origin of tetraploidy in Microsporidia. [PDF]

PLoS Biol
Khalaf A, Zhou C, Weber CC, Vancaester E, Sims Y, Makunin A, Mathers TC, Absolon DE, Wood JMD, McCarthy SA, Jaron KS, Blaxter M, Lawniczak MKN.   +12 more
europepmc   +5 more sources

Notch Activation Is Associated with Tetraploidy and Enhanced Chromosomal Instability in Meningiomas

Neoplasia: An International Journal for Oncology Research, 2008
The Notch signaling cascade is deregulated in diverse cancer types. Specific Notch function in cancer is dependent on the cellular context, the particular homologs expressed, and cross-talk with other signaling pathways.
Gilson S. Baia, Stefano Stifani, Edna T. Kimura, Michael W. McDermott, Russell O. Pieper, Anita Lal   +5 more
doaj   +2 more sources

Polyploidy is widespread in Microsporidia [PDF]

Microbiology Spectrum
Microsporidia are obligate intracellular eukaryotic parasites with an extremely broad host range. They have both economic and public health importance.
Amjad Khalaf, Mara K. N. Lawniczak, Mark L. Blaxter, Kamil S. Jaron   +3 more
doaj   +2 more sources

Tetraploidy [PDF]

, 2020
National Cancer Institute
  +4 more sources

The frequency and importance of polyploidy in tropical rainforest tree radiations. [PDF]

New Phytol
Summary The presence of more than two copies of the genome in an organism, termed ‘polyploidy’, is a crucial force in plant evolution, generating genetic, phenotypic and ecological diversity. [Correction added on 22 January 2026, after first online publication: the preceding sentence has been corrected.] The Amazonian tree flora is the most species ...
Schley RJ, Piñeiro R, Nicholls JA, Gaynor ML, Lewis GP, Fonseca Pezzini F, Dexter KG, Kidner C, Pennington RT, Twyford AD.   +9 more
europepmc   +3 more sources

Spindle Architectural Features Must Be Considered Along With Cell Size to Explain the Timing of Mitotic Checkpoint Silencing

Frontiers in Physiology, 2021
Mitosis proceeds through a defined series of events that is largely conserved, but the amount of time needed for their completion can vary in different cells and organisms.
Mathew Bloomfield, Jing Chen, Daniela Cimini   +2 more
doaj   +1 more source

Clinicopathological analysis of near-tetraploidy/tetraploidy acute myeloid leukaemia [PDF]

Journal of Clinical Pathology, 2015
Aims Near-tetraploidy/tetraploidy (NT/T) is a rare cytogenetic alteration in acute myeloid leukaemia (AML). NT/T-AML is categorised as complex cytogenetics and therefore, presumed to have an unfavourable prognosis. Our aim is to further characterise the clinical, morphological, cytogenetic and prognostic features of
Changlee S, Pang, Mark J, Pettenati, Timothy S, Pardee   +2 more
openaire   +2 more sources

Development of tetraploidy in salmonids

Genetics Selection Evolution, 1980
Refstie T
doaj   +4 more sources

Cytokinesis in Eukaryotic Cells: The Furrow Complexity at a Glance

Cells, 2020
The duplication cycle is the fascinating process that, starting from a cell, results in the formation of two daughter cells and it is essential for life.
Roberta Fraschini
doaj   +1 more source

Near-tetraploidy is associated with Richter transformation in chronic lymphocytic leukemia patients receiving ibrutinib

Blood Advances, 2017
: Ibrutinib is a highly effective targeted therapy for chronic lymphocytic leukemia (CLL). However, ibrutinib must be discontinued in a subset of patients due to progressive CLL or transformation to aggressive lymphoma (Richter transformation ...
Cecelia R. Miller, Amy S. Ruppert, Nyla A. Heerema, Kami J. Maddocks, Jadwiga Labanowska, Heather Breidenbach, Gerard Lozanski, Weiqiang Zhao, Amber L. Gordon, Jeffrey A. Jones, Joseph M. Flynn, Samantha M. Jaglowski, Leslie A. Andritsos, Kristie A. Blum, Farrukh T. Awan, Kerry A. Rogers, Michael R. Grever, Amy J. Johnson, Lynne V. Abruzzo, Erin K. Hertlein, James S. Blachly, Jennifer A. Woyach, John C. Byrd   +22 more
doaj   +1 more source