Results 21 to 30 of about 5,026 (197)
Notulae Scientia Biologicae, 2014 The present study was conducted to polyploidy possibility induction of two Iranian endemic mint (Mentha mozaffarianii) ecotypes. For this purpose, three experiments were done. The first experiment was factorial, based on completely randomized design with
Askar GHANI +4 more
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Agronomy, 2023 Polyploidy, frequently observed in citrus species, aids in achieving better adaptation to environmental stresses. In this context, the current work aims to develop stable tetraploids in citrus rootstock cultivars, viz., Rough lemon, Rangpur lime and ...
Vijayakumari Narukulla +4 more
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Tetraploidy causes chromosomal instability in acentriolar mouse embryos
Nature Communications, 2019 During cell division, tetraploidy can drive chromosomal instability (CIN) via supernumerary centrosomes, but it is unclear if this is the only route to CIN. Here the authors show that, in early mouse embryos, tetraploidy can drive chromosomal instability
Lia Mara Gomes Paim, Greg FitzHarris
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Journal of Developmental Biology, 2023 Whole genome duplication (WGD) or polyploidization can occur at the cellular, tissue, and organismal levels. At the cellular level, tetraploidization has been proposed as a driver of aneuploidy and genome instability and correlates strongly with cancer ...
Mara Schvarzstein +3 more
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Tetraploidy and tumor development
Oncotarget, 2014 Tetraploid cells, which contain a doubled chromosomal content, are known to facilitate tumorigenesis [1]. Two specific characteristics of tetraploid cells play major roles in promoting neoplastic transformation. First, proliferating tetraploid cells are genomically unstable and accumulate both numerical and structural chromosomal abnormalities.
Sanghee, Lim, Neil J, Ganem
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Addressing a weakness of anticancer therapy with mitosis inhibitors: Mitotic slippage
Molecular & Cellular Oncology, 2017 Mitosis inhibitors, which include antimicrotubule drugs, are chemotherapy agents that induce the arrest and apoptosis of mitotic cells. Mitotic slippage, in which mitotically arrested cells exit mitosis, limits the effectiveness of mitosis inhibitors. We
Riju S. Balachandran, Edward T. Kipreos
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100 Years of Chromosome Research in Rye, Secale L.
Plants, 2022 Although microscopy and genetics were still in their infancy, there are cytological results produced a hundred years ago that are still relevant today. Since the 1920s, rye has been a subject of chromosome research. It started by plotting its mitotic and
Rolf Schlegel
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Antioxidant defenses during early developmental stages in tetraploid rainbow trout, Oncorhynchus mykiss [PDF]
Caspian Journal of Environmental Sciences, 2023 Antioxidant defense status was examined during early developmental stages of rainbow trout, Oncorhynchus mykiss, as affected by heat shock (HS) treatment to induce tetraploidy.
Hajar Sadat Tabatabaei Pozveh +4 more
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Asymmetric clustering of centrosomes defines the early evolution of tetraploid cells
eLife, 2020 Tetraploidy has long been of interest to both cell and cancer biologists, partly because of its documented role in tumorigenesis. A common model proposes that the extra centrosomes that are typically acquired during tetraploidization are responsible for ...
Nicolaas C Baudoin +5 more
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The fate of extra centrosomes in newly formed tetraploid cells: should I stay, or should I go?
Frontiers in Cell and Developmental Biology, 2023 An increase in centrosome number is commonly observed in cancer cells, but the role centrosome amplification plays along with how and when it occurs during cancer development is unclear. One mechanism for generating cancer cells with extra centrosomes is
Mathew Bloomfield, Daniela Cimini
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